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Safety Advices
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English
UNSAFE
It is unsafe to consume alcohol with Roscan.
CONSULT YOUR DOCTOR
Roscan is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Roscan during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
It is not known whether Roscan alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
SAFE IF PRESCRIBED
Roscan is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Roscan may not be needed in these patients. Please consult your doctor.
UNSAFE
Roscan is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
"You should not take EUFLEX tablets if you have liver problems or if you are allergic to it. Women should not take EUFLEX tablets. https://hemonc.org/docs/packageinsert/flutamide.pdf
Medicine Overview of Roscan 250mg Tablet
Introduction
Roscan is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone. Roscan should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the...
... Show moreUses of Roscan
- Prostate cancer
Side effects of Roscan
Common
- Breast enlargement in male
- Sleepiness
- Nausea
- Abdominal pain
- Anemia (low number of red blood cells)
- Breast tenderness
- Constipation
- Decreased appetite
- Decreased libido
- Depression
- Dizziness
- Indigestion
- Flatulence
- Hot flashes
- Increased liver enzymes
- Rash
- Weakness
- Weight gain
How to use Roscan
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Roscan may be taken with or without food, but it is better to take it at a fixed time.
How Roscan works
Roscan blocks the effect of the natural male hormones on the growth of prostate cells. Roscan also blocks the undesired effects of androgens in females such as excessive hair growth and acne.
Quick Tips
- You have been prescribed Roscan for the treatment of prostate cancer.
- Take it with or without food, preferably at the same time every day.
- Do not drive or do anything requiring concentration unless you know how Roscan affects you.
- It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
- If you are diabetic, monitor your blood glucose regularly while taking Roscan.
- Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- Do not stop taking the medication without talking to your doctor first.
Brief Description
Indication
Prostate cancer
Administration
May be taken with or without food.
Adult Dose
Oral
Palliative treatment of prostatic carcinoma
Adult: 250 mg tid preferably at least 3 days before gonadorelin analogue treatment.
Contraindication
Hypersensitivity, severe hepatic impairment, pregnancy and lactation.
Mode of Action
Flutamide is a nonsteroidal 'pure' antiandrogen which acts directly on the target tissues either by blocking androgen uptake or by inhibiting cytoplasmic and nuclear binding of androgen.
Precaution
Perform liver function tests before starting treatment and at regular intervals. Treatment is not recommended in patients whose ALT values exceed twice the upper limit of normal. Regular assessment of prostate specific antigen level may help to monitor disease progression. Advise patient against discontinuing drug on their own. Exercise caution in patients with cardiac disease.
Lactation: Excretion in milk unknown; not recommended
Side Effect
>10%
Hot flashes (61%),Decreased libido (36%),Impotence (31%),Diarrhea (12%),Nausea/vomiting (11%)
1-10%
Gynecomastia (9%),Anorexia (4%),Edema (4%),Leukopenia (3%),Rash (3%)
Frequency Not Defined
Hemolytic anemia, methemoglobinemia
Increased AST, ALT, bilirubin, BUN
Pregnancy Category Note
Pregnancy Category: D
Lactation: Excretion in milk unknown; not recommended
Interaction
Increased prothrombin time in patients on long-term warfarin treatment.
