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Protolan 15
Beximco Pharmaceuticals Ltd.
Generic: Lansoprazole
Safety Advices
বাংলা
English
CAUTION
Caution is advised when consuming alcohol with Protolan 15. Please consult your doctor.
SAFE IF PRESCRIBED
Protolan 15 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Protolan 15 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Protolan 15 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Protolan 15 is safe to use in patients with kidney disease. No dose adjustment of Protolan 15 is recommended.
CAUTION
Protolan 15 should be used with caution in patients with severe liver disease. Dose adjustment of Protolan 15 may be needed. Please consult your doctor.
Medicine Overview of Protolan 15mg Capsule
Introduction
Protolan 15 is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as heartburn, acid reflux, peptic ulcer disease, and some other stomach conditions associated with excessive acid production. Protolan 15 is also used to prevent stomach ulcers and acidity that may be seen with the prolonged use of pain-killers. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine should be taken one hour before a meal, preferably in the morning. The dose will depend on your underlying...
... Show moreUses of Protolan 15
- Gastroesophageal reflux disease (Acid reflux)
- Peptic ulcer disease
Side effects of Protolan 15
Common
- Nausea
- Headache
- Flatulence
- Diarrhea
How to use Protolan 15
Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Protolan 15 is to be taken empty stomach.
How Protolan 15 works
Protolan 15 is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
What if you forget to take Protolan 15?
If you miss a dose of Protolan 15, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- It is a well-tolerated medicine and provides relief for a long time.
- Junior Lanzol 30mg Tablet DT should be taken 1 hour before a meal, preferably in the morning.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use of Junior Lanzol 30mg Tablet DT can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Brief Description
Indication
Peptic ulcer, H.pylori infection, Gastro-oesophageal reflux disease, Hypersecretory conditions, Acid-related dyspepsia, NSAID-induced ulcers, Erosive oesophagitis
Administration
Should be taken on an empty stomach. Take before meals.
Adult Dose
Oral Peptic ulcer Adult: 30 mg once daily in the morning given for up to 4 wk (duodenal ulcer) or for up to 8 wk (gastric ulcer). Maintenance: 15 mg/day. Zollinger-Ellison syndrome Adult: Initially, 60 mg once daily in the morning and adjust as required. Daily doses >120 mg should be given in 2 divided doses. Acid-related dyspepsia Adult: 15-30 mg once daily in the morning for 2-4 wk. Gastro-oesophageal reflux disease Adult: 15-30 mg once daily in the morning for 4-8 wk. Maintenance: 15-30 mg once daily according to response. Prophylaxis of NSAID-induced ulcers Adult: 15-30 mg once daily...
... Show moreChild Dose
Oral Gastro-oesophageal reflux disease 1-11 yr 30 kg: 30 mg once daily in the morning for up to 12 wk. May increase doses up to 30 mg bid if patient is still symptomatic after 2 or more wk of treatment. 12-17 yr 15 mg once daily for up to 8 wk. Erosive oesophagitis 1-11 yr 30 kg: 30 mg once daily in the morning for up to 12 wk. May increase doses up to 30 mg bid if patient is still symptomatic after 2 or more wk of treatment. 12-17 yr 30 mg once daily for up to 8 wk....
... Show moreRenal Dose
Renal impairment: No dosage adjustment needed.
Contraindication
Hypersensitivity.
Mode of Action
Lansoprazole is a substituted benzimidazole, and is also known as PPI due to its property to block the final step of acid secretion by inhibiting H+/K+ ATPase enzyme system in gastric parietal cell. Both basal and stimulated acid are inhibited.
Precaution
Hepatic impairment. Gastric malignancy should be ruled out. Pregnancy and lactation.
Lactation
Risk Summary
There is no information regarding presence of lansoprazole in human milk, effects on breastfed infant, or on milk production; however, lansoprazole and its metabolites are present in rat milk; developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and any potential adverse effects on breastfed child from treatment or from underlying maternal condition.
Side Effect
1-10%
Headache (3-7%),Diarrhea (1-5%),Constipation (1-5%),Nausea (1-3%),Abdominal pain (1-3%)
<1%
Anxiety,Angina,Palpitations,Syncope,Edema,Anorexia,Dry mouth,Tenesmus,Flatulence,Melena,Myalgia,Tinnitus,Allergic reaction
Pregnancy Category Note
Risk Summary Available data from published observational studies overall do not indicate an association of adverse pregnancy outcomes with lansoprazole treatment; estimated background risk of major birth defects and miscarriage for the indicated populations are unknown Available data from published observational studies failed to demonstrate an association of adverse pregnancy-related outcomes and lansoprazole use; methodological limitations of these observational studies cannot definitely establish or exclude any drug-associated risk during pregnancy No adverse effects on embryo-fetal development occurred in studies performed in pregnant rats at oral lansoprazole doses up to 150 mg/kg/day (40 times the recommended human dose [30 mg/day] based...
... Show moreInteraction
Increased risk of hypomagnesaemia w/ diuretics and digoxin. May decrease plasma concentration of erlotinib, dasatinib and lapatinib. May decrease the bioavailability of itraconazole and ketoconazole. May increase plasma concentration of cilostazol and methotrexate. Reduced bioavailability w/ antacids and sucralfate.
Potentially Fatal: May decrease serum levels and pharmacological effects of rilpivirine and atazanavir.
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