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Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Aromatin 1. Please consult your doctor.
CONSULT YOUR DOCTOR
Aromatin 1 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
UNSAFE
Aromatin 1 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
UNSAFE
Aromatin 1 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Aromatin 1 should be used with caution in patients with severe kidney disease. Dose adjustment of Aromatin 1 may be needed. Please consult your doctor.
Limited information is available on the use of Aromatin 1 in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
CAUTION
Aromatin 1 should be used with caution in patients with liver disease. Dose adjustment of Aromatin 1 may be needed. Please consult your doctor.
Limited information is available on the use of Aromatin 1 in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Medicine Overview of Aromatin 1mg Tablet
Introduction
Aromatin 1 is used alone or with other treatments, such as surgery or radiation, to treat early breast cancer in postmenopausal women. It can also be used as the first line treatment of advanced breast cancer that has spread within the breast or to other areas of the body. Aromatin 1 belong to a class of drug called aromatase inhibitors, which decreases the amount of estrogen in the body. It should be taken with or without food, but take it at the same time every day to get the most benefit. It should be taken as your doctor's advice. The...
... Show moreUses of Aromatin 1
- Breast cancer
Side effects of Aromatin 1
Common
- Headache
- Musculoskeletal (bone, muscle or joint) pain
- Nausea
- Osteoporosis
- Skin rash
- Weakness
How to use Aromatin 1
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aromatin 1 may be taken with or without food, but it is better to take it at a fixed time.
How Aromatin 1 works
Aromatin 1 is an aromatase inhibitor. It works by lowering the amount of estrogen (natural female hormone) produced in the body. This can lower or stop the growth of some breast cancer cells that need estrogen to grow.
What if you forget to take Aromatin 1?
If you miss a dose of Aromatin 1, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Aromatin 1 is used for the treatment of hormone dependent breast cancer in postmenopausal women.
- Take it at the same time everyday.
- It may cause weakness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- Nausea may occur on starting treatment with this medicine but should go away with time. If nausea is bothersome, take it after meal.
- Your doctor may regularly check your Vitamin D level and bone mineral density and suggest supplements, if needed.
- Do not take Aromatin 1 if you are pregnant or breastfeeding.
Brief Description
Indication
Oral
Advanced or locally advanced breast cancer, Adjuvant treatment in early breast cancer
Adult: In postmenopausal women: 1 mg daily. Adjuvant treatment may be continued for up to 5 yr.
Hepatic Impairment
Mild-to-moderate impairment or stable hepatic cirrhosis: Dose adjustment not necessary
Severe hepatic impairment: Not studied
Administration
Efficacy decreased by oestrogens. Plasma concentrations decreased by tamoxifen.
Adult Dose
Moderate or severe hepatic impairment, hyperlipidaemias. Laboratory test for menopause if status is doubtful. Bone mass density test should be conducted at the start of the therapy and at regular intervals thereafter.
Lactation: Unknown whether drug is excreted in milk; not recommended given potential for serious adverse reactions in nursing infants
Renal Dose
Anastrozole prevents conversion of androstenedione to estrone and testosterone to oestradiol by inhibiting aromatase, thus leading to significantly reduced serum oestradiol concentrations.
Mode of Action
May be taken with or without food.
Precaution
Breast cancer, Ovulation induction
Pregnancy Category Note
>10%
Hot flashes (12-36%),Vasodilation (25-36%),Fatigue (19%),Mood disturbances (19%),Nausea and vomiting (19%),Weakness (16-19%),Arthritis (17%),Pain (17%),Arthralgia (2-15%),Pharyngitis (14%),Depression (13%),Hypertension (2-13%),Bone pain (11%),Increased cough (11%),Osteoporosis (11%),Rash (8-11%)
1-10%
Accidental injury (10%),Back pain (10%),Fracture (10%),Headache (10%),Insomnia (10%),Peripheral edema (10%),Dyspnea (8-10%),Abdominal pain (9%),Infection (9%),Lymphedema (9%),Diarrhea (8-9%),Constipation (7-9%),Breast pain (8%),Dizziness (8%),Urinary tract infection (8%),Chest pain (7%),Dyspepsia (7%),Paresthesia (5-7%),Anxiety (6%),Cataracts (6%),Flu syndrome (6%),Sinusitis (6%),Vulvovaginitis (6%),Xerostomia (6%),Breast neoplasm (5%),Bronchitis (5%),Cyst (5%),Diaphoresis (5%),Neoplasm (5%),Vaginal bleeding (5%),Fractures of spine, hip, or wrist (4%),Ischemic cardiovascular disease (4%),Vaginal hemorrhage (4%),Vaginitis (4%),Leukorrhea (3-4%),Deep vein thrombosis (2%),Endometrial cancer (intact uterus at baseline) (2%),Ischemic cerebrovascular event (2%),Weight gain (2%),Lethargy (1%)
Interaction
Pregnancy. Hypersensitivity, premenopausal women.
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