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Purinol

Tablet-(300mg)
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Drug International Ltd.

Generic: Allopurinol

1 Tablet
৳ 7.48
৳ 8.05
7% OFF
Alternative Brands For Purinol

Medicine Overview of Purinol 300mg Tablet

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Introduction

Purinol is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which can appear around your joints and kidneys and cause pain. This medicine helps to keep uric acid levels low. Purinol should be taken after food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because more crystals form in your joints and kidneys. You can help yourself by making some changes to your diet and drinking plenty of fluids. Some of the common side effects of this medicine are rash, nausea, and diarrhea. Your doctor may help with ways to reduce or prevent these symptoms. Some people may get a severe allergic reaction which needs urgent medical attention. Talk to your doctor straight away if you get symptoms of liver disease including nausea that does not stop, yellowing skin or eyes, or dark urine. To make sure it is safe for you, before taking this medicine, let your doctor know if you have or have had heart failure, heart problems, stroke, kidney or liver disease or thyroid problems. Do not use this medicine if you are pregnant or breastfeeding. Check with your doctor. You will be asked for regular blood tests to check that your liver is working properly.

Uses of Purinol

  • Gout

Side effects of Purinol

Common
  • Skin rash
  • Diarrhea
  • Nausea

How to use Purinol

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Purinol is to be taken with food.

How Purinol works

Purinol is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

What if you forget to take Purinol?

If you miss a dose of Purinol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • Your doctor has prescribed Purinol to reduce episodes of gout attack.
  • Take Purinol with food to avoid stomach upset.
  • Take plenty of fluids (2-3 litres) daily while on Purinol.
  • Notify your doctor if you develop a rash. This could be a sign of allergy and should go away on discontinuing Purinol.
  • When you first start taking this medicine, you might have more gout attacks. Do not stop Purinol on having an acute attack of gout as that could make an attack worse.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not consume alcohol while taking this medicine as it may cause your gout to flare up.

Brief Description

Indication

Adult: PO Gout; Hyperuricaemia Mild: 100 mg/day PO initially; increased weekly to 200-300 mg/day Moderate to severe: 100 mg/day PO initially; increased weekly to 400-600 mg/day Prevention of hyperuricaemia associated w/ chemotherapy treatment or enzyme disorders 600-800 mg/day, starting 2-3 days before cancer treatment. Hepatic impairment: Dose reduction may be needed. Monitor liver function regularly.

Administration

May inhibit the metabolism of mercaptopurine and azathioprine; reduce dose of mercaptopurine and azathioprine when given w/ allopurinol. May increase effect of warfarin and other coumarin anticoagulants. Increased excretion of the oxipurinol (metabolite) w/ salicylates or uricosuric agents. Increased toxicity w/ thiazide diuretics, some antibacterials, other antineoplastics, ciclosporin, some sulfonylurea antidiabetics, theophylline and vidarabine.

Adult Dose

Ensure adequate fluid intake. Prophylactically with an anti-inflammatory or colchicine for at least 1 mth. Withdraw immediately when sensitivity (skin rash, etc) appears. Pregnancy, lactation. Hepatic and renal impairment. Lactation: Agent is distributed into breast milk; use with caution.

Renal Dose

Allopurinol is an inhibitor of the enzyme xanthine oxidase which converts hypoxanthine to xanthine then uric acid. The reduced production of uric acid relieves all symptoms associated with hyperuricaemia and gout. Inhibition of xanthine oxidase leads to accumulation of its substrates hypoxanthine and xanthine but since their renal clearance is more than 10 times that of uric acid, there is no risk of nephrolithiasis.

Mode of Action

Administration Should be taken with food. Take immediately after meals.

Precaution

Hyperuricaemia, Uric acid nephropathy, Cancer therapy-induced hyperuricaemia, Gout, Recurrent renal stones

Side Effect

Renal impairment: Haemodialysis: Administer dose after session or administer 50% supplemental dose. CrCl (ml/min) 10-20 200 mg daily. <3 100 mg daily at extended intervals. 3-10 100 mg daily.

Pregnancy Category Note

1-10% Rash (1.5%),Nausea (1.3%),Renal failure (1.2%),Vomiting (1.2%) Frequency Not Defined Amblyopia,Arthralgias,Blood dyscrasias,Bronchospasm,Cardiovascular abnormalities,Cataracts,Confusion,Decrease in libido,Dizziness,Ecchymosis,Electrolyte abnormalities,Epistaxis,Foot drop,Hematuria,Hepatotoxicity,Hypotonia,Iritis,Kidney function abnormality,Macular retinitis,Malaise,Neuritis,Pharyngitis,Pruritus,Skin edema,Stevens-Johnson syndrome,Sweating,Tinnitus Potentially Fatal: Stevens-Jonhson and/or Lyell's Syndrome (urticaria, fever, lymphadenopathy, arthralgia). Occasionally, thrombocytopaenia, agranulocytosis and aplastic anaemia.

Interaction

Hypersensitivity; acute attack of gout.

Buy Purinol from Arogga

In Bangladesh, you can get the original Purinol. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Purinol in Bangladesh?

The latest price of Purinol in Bangladesh is 7.48৳. You can buy Purinol at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CAUTION
Caution is advised when consuming alcohol with Purinol. Please consult your doctor.
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CONSULT YOUR DOCTOR
Purinol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Purinol is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
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UNSAFE
Purinol may cause side effects which could affect your ability to drive. Occasionally drowsiness, dizziness or vertigo, ataxia and visual disturbances, may occur when taking Purinol. This may affect your driving ability.
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CAUTION
Purinol should be used with caution in patients with kidney disease. Dose adjustment of Purinol may be needed. Please consult your doctor.
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CAUTION
Purinol should be used with caution in patients with liver disease. Dose adjustment of Purinol may be needed. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.