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Relafin 50
General Pharmaceuticals Ltd.
Generic: Fluvoxamine Maleate
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Relafin 50.
CONSULT YOUR DOCTOR
Relafin 50 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Relafin 50 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
SAFE
Relafin 50 does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Relafin 50 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Relafin 50 may not be needed in these patients. Please consult your doctor.
CAUTION
Relafin 50 should be used with caution in patients with liver disease. Dose adjustment of Relafin 50 may be needed. Please consult your doctor.
Medicine Overview of Relafin 50mg Tablet
Introduction
Relafin 50 is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed to treat depression, where it helps to make you feel better. This medicine is also used to treat people with obsessive-compulsive disorder. Relafin 50 can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without...
... Show moreUses of Relafin 50
- Depression
- Obsessive-compulsive disorder
Side effects of Relafin 50
Common
- Delayed ejaculation
- Drowsiness
- Erectile dysfunction
- Low sexual desire
- Nausea
- Vomiting
- Dryness in mouth
- Fatigue
- Increased sweating
- Indigestion
- Insomnia (difficulty in sleeping)
- Loss of appetite
- Nervousness
- Tremor
How to use Relafin 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Relafin 50 may be taken with or without food, but it is better to take it at a fixed time.
How Relafin 50 works
Relafin 50 is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of obsessive-compulsive disorders.
What if you forget to take Relafin 50?
If you miss a dose of Relafin 50, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- It should be taken at night with or without food.
- Take caution while taking Relafin 50 if you are using Benzodiazepines and MAO inhibitors previously.
- Do not drive or do anything requiring concentration until you know how Relafin 50 affects you.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking the medication suddenly without talking to your doctor.
Brief Description
Indication
Major depressive disorder, Anxiety disorders, Depression, Panic disorder, Obsessive-compulsive disorder, Posttraumatic stress disorder
Administration
May be taken with or without food.
Adult Dose
Oral
Obsessive compulsive disorder
Adult: 50 mg once daily; may increase by 50 mg every 4-7 days. Daily doses >100 mg should be given in 2 divided doses. Max: 300 mg daily.
Elderly: Initial 25mg once daily.
Depression
Adult: Initially, 50-100 mg daily, may increase gradually up to 300 mg daily, if necessary. Doses >150 mg should be given in 2 or 3 divided doses.
Hepatic impairment: Decrease dose
Child Dose
Oral
Obsessive compulsive disorder
Child: >8 yr: 25 mg once daily, may increase by 25 mg every 4-7 days. Doses >50 mg should be given in 2 divided doses.
Reassess if no improvement after 10 wk of treatment. Max: 200 mg daily.
Contraindication
Hypersensitivity. Not to be used with thioridazine, terfenadine, astemizole, cisapride, pimozide, aloestron, tizanidine. Lactation.
Mode of Action
Fluvoxamine, derived from aralkylketone, inhibits the re-uptake of serotonin in brain neurons.
Precaution
History of mania or seizures; liver dysfunction; presence of depressive symptoms; smokers. Treatment with MAOI should only be started at least 2 wk after stopping fluvoxamine treatment. Increased risk of suicidal ideation and behaviour when used in children, adolescents and young adults <24 yr. Pregnancy, elderly; operating hazardous machinery; withdraw gradually. Monitor prothrombin time in patients who are taking oral anticoagulants concurrently.
Lactation
Present in breast milk; avoid
Side Effect
>10%
Nausea (40%),Headache (22-35%),Somnolence (22-27%),Weakness (14-26%),Insomnia (20-35%),Diarrhea (11-18%),Dizziness (11-15%),Xerostomia (10-14%),Anorexia (6-14%),Abnormal ejaculation (8-11%)
1-10%
Pain (10%),Dyspepsia (8-10%),Constipation (4-10%),Decreased libido (2-10%),Upper respiratory infections (9%),Anxiety (5-8%),Tremor (5-8%),Sweating (6-7%),Vomiting (4-6%),Abdominal pain (5%),Myalgia (5%),Abnormal taste (2-5%),Bruising (4%),Abnormal dreams (3%),Abnormal thinking (3%),Chest pain (3%),Palpitation (3%),Agitation (2-3%),Vasodilation (2-3%),Hypertension (1-2%),Increased LFTs (1-2%),Weight change (1-2%),Manic reaction
<1%
Activation of mania/hypomania, seizures (discontinue),Sinusitis
Frequency Not Defined
Edema,Amnesia,Apathy,Asthenia,Malaise,Nervousness,Dry mouth,Myoclonus,Cough
Pregnancy Category Note
Pregnancy Prolonged experience with fluvoxamine in pregnant women over decades, based on published observational studies, have not identified a clear drug-associated risk of major birth defects or miscarriage; there are risks associated with untreated depression in pregnancy and risks of persistent pulmonary hypertension of newborn (PPHN) and poor neonatal adaptation with exposure to selective serotonin reuptake inhibitors (SSRIs), including fluvoxamine, during pregnancy Women who discontinue antidepressants during pregnancy are more likely to experience a relapse of major depression than women who continue antidepressants; consider risk of untreated depression when discontinuing or changing treatment with antidepressant medication during pregnancy and postpartum...
... Show moreInteraction
Co-admin with fluvoxamine may increase carbamazepine toxicity and serum levels of theophylline. Lithium enhances the serotonergic effects of fluvoxamine. Anticoagulants may require dosage adjustments. Diltiazem with fluvoxamine may lead to bradycardia. Avoid alcohol.
Potentially Fatal: Fluvoxamine should not be used in combination with MAOIs, or within 14 days of discontinuing treatment with MAOIs.
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