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Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Relaxtion. Please consult your doctor.
CONSULT YOUR DOCTOR
Relaxtion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Relaxtion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
NOT RELEVANT
Not relevant, as Relaxtion is intended for use in hospitalised patients.
SAFE IF PRESCRIBED
Relaxtion is safe to use in patients with kidney disease. No dose adjustment of Relaxtion is recommended.
SAFE IF PRESCRIBED
Relaxtion is safe to use in patients with liver disease. No dose adjustment of Relaxtion is recommended.
Medicine Overview of Relaxtion 25mg/2.5ml Injection
Introduction
Relaxtion belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care. Relaxtion is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. The most common side effects of this medicine include skin flush, skin redness, and itching. It may also cause pain, redness, and swelling...
... Show moreUses of Relaxtion
- Skeletal mucle relaxation during surgery
Side effects of Relaxtion
Common
- Itching
- Skin rash
- Erythema (skin redness)
- Injection site reactions (pain, swelling, redness)
How to use Relaxtion
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Relaxtion works
Relaxtion relaxes the muscles by blocking the impulses from the nerves.
Quick Tips
- Relaxtion is given as an injection by the healthcare professional.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- You may get pain, itching, redness or discomfort at the site of the injection. Inform your doctor if it does not go away or bothers you.
- It is advisable to avoid driving or machinery work for a period of 24 hours after taking this medicine.
Brief Description
Indication
Intravenous Muscle relaxant in general anaesthesia, Endotracheal intubation, Aid controlled ventilation Adult: Initially, 300-600 mcg/kg as inj. Subsequently, 100-200 mcg/kg when necessary or every 15-25 minutes for maintenance in prolonged procedures. Alternatively, maintenance can also be achieved by continuous infusion at 5-10 mcg/kg/minute. Initial dose should be given over 60 seconds in patients with CV disease. Dose should be calculated based on ideal body-weight in obese patients. Special Populations: For patients with significant CV disease or any history (e.g. severe anaphylactoid reactions or asthma) suggesting a greater risk of histamine release, an initial dose of 0.3-0.4 mg/kg should be given...
... Show moreAdministration
Mixed block with suxamethonium which is difficult to reverse with anticholinergic drugs. Ketamine may potentiate the effects of atracurium. Concurrent use with tamoxifen or danazol may prolong effects of atracurium.
Potentially Fatal: Neuromuscular blockade potentiated by parenteral Mg salts, anaesthetics, aminoglycosides and polypeptide antibiotics, botulinum A toxin. Malignant hyperthermia with halogenated anaesthetics and succinylcholine. MAOIs.
Adult Dose
Neonates; severe CVS disorders; renal or hepatic dysfunction; myasthenia gravis and other neuromuscular disorders; severe electrolyte imbalances; respiratory insufficiency or pulmonary disease, asthma; burns; cardiopulmonary bypass; smoking; pregnancy and lactation. Dosage for obese patients should be based on ideal body-weight to prevent overdosing.
Renal Dose
Atracurium besilate blocks neural transmission at the neuromuscular junction by competitive binding at the cholinergic receptor sites on the motor end plate.
Contraindication
Intravenous
Muscle relaxant in general anaesthesia, Endotracheal intubation, Aid controlled ventilation
Child: >2 mth: Initially, 400-500 mcg/kg as inj. Maintenance dose: 80-100 mcg/kg; first maintenance dose may be given 20-45 min after the initial dose, subsequently, may be repeated every 15-25 min.
For children 1 mth-2 yr: 300-400 mcg/kg may be used as initial dose in those who are under halothane anaesthesia. Maintenance doses may be admin more frequently in infant and children than adults.
Precaution
General anaesthesia, Endotracheal intubation, Aid controlled ventilation
Pregnancy Category Note
Cutaneous reactions; bradycardia, transient hypotension in patients with CVS disorders; dyspnoea, bronchospasm; rash and urticaria.
Interaction
Hypersensitivity.