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Rosalin
Incepta Pharmaceuticals Ltd.
Generic: Oxymetazoline Hydrochloride topical
Medicine Overview of Rosalin 1% Cream
বাংলা
English
Indication
Rosacea,
Indicated for the topical treatment of persistent facial erythema associated with rosacea in adults.
Administration
Apply a pea-sized amount of the cream, in a thin layer to cover the entire face avoiding eyes and lips.,
Adult Dose
Rosacea
Indicated for the topical treatment of persistent facial erythema associated with rosacea in adults.
Apply topically once daily; apply a pea-sized amount of cream in a thin layer to cover the entire face (forehead, nose, each cheek, and chin), avoiding the eyes and lips
Apply a pea-sized amount of the cream, once daily, in a thin layer to cover the entire face avoiding eyes and lips.
Child Dose
<18 years: Safety and efficacy not established
Mode of Action
Oxymetazoline Hydrochloride is an alpha1A adrenoreceptor agonist and acts as a vasoconstrictor of the cutaneous microvasculature.
Precaution
• Alpha-adrenergic agonists may impact blood pressure. Advise patients with cardiovascular disese, orthostatic hypotension and/or uncontolled hypertension or hypotension to seek medical care if their condition worsens.
• Use with caution in patients with cerebral or coronary insufficiency, Raynaud’s phenomenon, thromboangiitis obliterans, scleroderma or Sjögren’s syndrome and advise patients to seek medical care if signs and symptoms of potentiation of vascular insufficiency develop.
• Advise patients to seek immediate medical care if signs and symptoms of acute narrow-angle glaucoma develop.
Side Effect
1-10%
Application-site dermatitis (2%)
Worsening inflammatory lesions of rosacea (1%)
Application-site pruritus (1%)
Application-site erythema (1%)
Application-site pain (1%)
Pregnancy Category Note
Pregnancy
No available data on oxymetazoline topical use in pregnant women to inform a drug-associated risk for major birth defects and miscarriage
Data describing intranasal decongestant use in pregnant women identified a potential association between second-trimester exposure to oxymetazoline (with no decongestant exposure in the first trimester) and renal collecting system anomalies.
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