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Rythmosin
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Propafenone Hydrochloride
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rythmosin. Please consult your doctor.
CONSULT YOUR DOCTOR
Rythmosin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Rythmosin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Rythmosin may cause side effects which could affect your ability to drive.
As Rythmosin may cause tiredness, dizziness, blurred vision and low blood pressure in some patients and this may affect your ability to drive.
SAFE IF PRESCRIBED
Rythmosin is safe to use in patients with kidney disease. No dose adjustment of Rythmosin is recommended.
However, talk to your doctor if you have any underlying kidney disease.
CAUTION
Rythmosin should be used with caution in patients with liver disease. Dose adjustment of Rythmosin may be needed. Please consult your doctor.
Medicine Overview of Rythmosin 150mg Tablet
Introduction
Rythmosin is a medicine used to treat arrhythmia (abnormal heart rhythm). It restores normal heart rhythm by blocking abnormal electrical signals in the heart. This helps to maintain a regular and steady heartbeat. Rythmosin should be taken regularly as advised by the doctor. You should take it with food and at a fixed time. This medicine should not be stopped abruptly without consulting the doctor as this can worsen your condition. Regular follow-up with your doctor is advised while using this medicine. It may cause side effects like dizziness, headache, blurred vision, nausea, constipation and fatigue in some patients. Your...
... Show moreUses of Rythmosin
- Arrhythmia
Side effects of Rythmosin
Common
- Abdominal pain
- Anxiety
- Blurred vision
- Breathlessness
- Chest pain
- Constipation
- Dizziness
- Dryness in mouth
- Fatigue
- Fever
- Headache
- Increased liver enzymes
- Palpitations
- Sleep disorder
- Taste change
- Visual impairment
- Vomiting
- Weakness
How to use Rythmosin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rythmosin is to be taken with food.
How Rythmosin works
Rythmosin is an anti-arrhythmic medication. It works by blocking abnormal electrical signals in the heart to correct irregular heartbeat to a normal rhythm.
What if you forget to take Rythmosin?
If you miss a dose of Rythmosin, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- It may cause dizziness. Do not drive or perform activities require mental focus until you know how it affects you.
- Do not start any medicine including prescription or over-the-counter medicines without informing your doctor, as they may alter Rythmosin levels in your body.
- Your doctor may get blood tests done to check your sodium and potassium levels, kidney function, and lung function before starting treatment with this medicine.
- Your doctor may regularly monitor blood sugar level while taking this medicine.
- Inform your doctor if you experience slow or fast heart rate, chest pain, shortness of breath.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Do not stop taking medication suddenly without talking to your doctor.
Brief Description
Indication
Supraventricular and ventricular arrhythmias, Atrial Fibrillation/Flutter
Administration
Should be taken with food. Take after meals. Swallow whole, do not chew/crush.
Adult Dose
Oral
Supraventricular and ventricular arrhythmias, Atrial Fibrillation/Flutter
Adult:
For immediate-release tablet: Usual initial doses: 150 mg tid, may increase at intervals of 3-4 days up to 300 mg tid.
Dose reduction is recommended in patients weighing <70 kg.
Elderly: Dose reduction is recommended.
Hepatic impairment: Dose reduction is recommended.
Child Dose
Safety and efficacy not established
Contraindication
Uncontrolled heart failure, marked hypotension, severe bradycardia and heart block, conduction abnormalities, cardiogenic shock, myasthenia gravis.
Mode of Action
Propafenone is a class 1C antiarrhythmic drug with local anaesthetic effects, and a direct stabilising action on myocardial membranes. The electrophysiological effect manifests itself in a reduction of upstroke velocity (Phase 0) of the monophasic action potential. In Purkinje fibers, and to a lesser extent myocardial fibers, propafenone reduces the fast inward current carried by sodium ions. Diastolic excitability threshold is increased and effective refractory period prolonged. Propafenone reduces spontaneous automaticity and depresses triggered activity.
Precaution
Severe pulmonary obstructive diseases, CHF, cardiac pacemaker, impaired renal/hepatic function, pregnancy, lactation, elderly. Correct electrolyte disturbances before starting treatment. May worsen heart failure in patients with preexisting organic heart disease. May worsen or cause new severe ventricular arrhythmias e.g. ventricular tachycardia or fibrillation. May aggravate electrically induced ventricular tachycardia in some patients.
Lactation: Crosses into breast milk; discontinue drug or do not nurse
Side Effect
>10%
Unusual taste (7-23%),Dizziness/lightheadedness (7-15%),N/V (3-11%)
1-10%
Constipation (4-8%),Headache (2-6%),Intraventricular conduction delay (4%),Fatigue (6%),Blurred vision (3%),Weakness (3%),Dyspnea (2%),Wild complex tachycardia (2%),Bradycardia (2%),Palpitations (2%),Tremor (2%),Anorexia (2%),Diarrhea (2%),Ataxia (2%),1°AV block (2-5%),Angina (5%),Palpitations (3%),CHF (2-3% ),Chest pain (2%),Bradyarrhythmia (2%),AF (1%),Bundle branch block (1%),2nd degree AV block (1%),Hypotension (1%),Sinus arrest (1%)
Frequency Not Defined
Lethargy,Rash,Dyspepsia,Dry mouth,Agranulocytosis,Hepatotoxicity (rare),Systemic lupus erythematosus (rare),Bronchospasm (rare)
Potentially Fatal: SA/AV or intraventricular blocks. Severe hypotension, especially in elderly.
Interaction
Effect may be potentiated by local anesth, beta-blockers, TCA. May increase plasma level of propranolol, metoprolol, desipramine, cyclosporin, digoxin, theophylline. Plasma conc may rise when taken simultaneously w/ cimetidine or quinidine. May enhance effect of anticoagulant. Simultaneous administration w/ phenobarb or rifamycin may decrease propafenone plasma conc, possibly in sub-therapeutic levels.
ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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