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Sentix 1
Eskayef Pharmaceuticals Ltd.
Generic: Flupenthixol (flupentixol)
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Sentix 1.
CONSULT YOUR DOCTOR
Sentix 1 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Sentix 1 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Sentix 1 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CONSULT YOUR DOCTOR
There is limited information available on the use of Sentix 1 in patients with kidney disease. Please consult your doctor.
However, there have been reports of some side effects in patients with severe kidney disease.
CAUTION
Sentix 1 should be used with caution in patients with liver disease. Dose adjustment of Sentix 1 may be needed. Please consult your doctor.
Medicine Overview of Sentix 1 1.0mg Tablet
Introduction
Sentix 1 is a prescription medicine used in the treatment of schizophrenia. It may also be used to treat depression and bipolar disorder. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave. Sentix 1 may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as...
... Show moreUses of Sentix 1
- Schizophrenia
Side effects of Sentix 1
Common
- Sleepiness
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Dryness in mouth
- Abnormality of voluntary movements
- Weight gain
- Increased prolactin level in blood
- Urinary retention
- Constipation
- Muscle stiffness
- Tremor
How to use Sentix 1
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sentix 1 may be taken with or without food, but it is better to take it at a fixed time.
How Sentix 1 works
Sentix 1 is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.
Quick Tips
- You have been prescribed Sentix 1 for the treatment of schizophrenia.
- Take it at bedtime to avoid feeling sleepy during the day.
- Use caution while driving or doing anything that requires concentration as Sentix 1 can cause dizziness and sleepiness.
- Avoid drinking alcohol while taking this medicine as it can make drowsiness worse.
- Inform your doctor if you experience any abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
- It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
- Don't stop taking Sentix 1 without talking to your doctor first as it may cause worsening of symptoms.
Brief Description
Indication
Depression, Schizophrenia, Psychoses
Administration
May be taken with or without food.
Adult Dose
Oral Psychoses Adult: Initially, 3-9 mg bid, adjusted according to response. Max: 18 mg daily. Elderly: Initial dose: ¼ or ½ of the usual initial dose. Oral Depression with or without anxiety Adult: Initially, 1 mg daily increased after 1 wk to 2 mg daily and then to a max of 3 mg daily, last dose should be given not later than 4 p.m. Doses >2 mg should be given in 2 divided doses. Discontinue treatment if there is no improvement within 1 wk of using the max dose. Elderly: Initially, 0.5 mg daily increased after 1 wk to 1...
... Show moreContraindication
Hypersensitivity. Extremely excitable and overactive patients; mania; porphyria; coma; preexisting CNS depression; bone-marrow supression; phaeochromocytoma. Lactation.
Mode of Action
Flupentixol is a thioxanthene antipsychotic that inhibits dopamine-mediated effects by blocking postsynaptic dopamine receptors in the CNS.
Precaution
Patients with convulsive disorders; advanced hepatic, renal, CV or resp disease; tasks requiring mental alertness; elderly (especially with dementia), and debilitated patients; neuroleptics with sedative effect must be withdrawn gradually; history of angle-closure glaucoma; urinary retention; prostatic hyperplasia; breast cancer, prolactin dependent tumours; parkinsonism; myasthenia gravis; pregnancy; Avoid direct sunlight.
Side Effect
Rigidity, tremors, restlessness, tardive dyskinesia, insomnia, dryness of mouth, wt gain, sexual dysfunction, galactorrhoea and menstrual disturbances.
Potentially Fatal: Neuroleptic malignant syndrome (hyperthermia, hypertonicity of skeletal muscles, unconsciousness and autonomic nervous system instability).
Pregnancy Category Note
Pregnancy category: C
Lactation: Drug enters breast milk; not recommended
Interaction
May potentiate the adverse effects of drugs with antimuscarinic effects e.g. TCAs. Reduced efficacy of levodopa. Increases adverse extrapyramidal symptoms with dopamine antagonists (metoclopramide and prochlorperazine).
Potentially Fatal: Potentiates CNS effects of alcohol, general anaesthetics, hypnotics, anxiolytics and opioids. Blocks antihypertensive effect of guanethidine.
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