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Sevel

Tablet-(400mg)
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The ACME Laboratories Ltd.

Generic: Sevelamer Hydrochloride/Carbonate

1 Tablet
৳ 41.03
৳ 45.13
9% OFF
Alternative Brands For Sevel

Medicine Overview of Sevel 400mg Tablet

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Introduction

Sevel is used to treat increased phosphate level in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood. Sevel should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get maximum benefit of the medicine. Using of Sevel may cause side effects such as nausea, vomiting, abdominal pain, constipation and diarrhea. You may also develop low levels of calcium, folic acid and vitamins A, D, E and K in your blood. Take necessary supplements as advised by your doctor.

Uses of Sevel

  • High phosphate levels in blood

Side effects of Sevel

Common
  • Nausea
  • Vomiting
  • Upper abdominal pain
  • Flatulence
  • Constipation
  • Diarrhea

How to use Sevel

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sevel is to be taken with food.

How Sevel works

Sevel inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.

What if you forget to take Sevel?

If you miss a dose of Sevel, skip it and continue with your normal schedule. Do not double the dose.

Quick Tips

  • Sevel is used to control blood phosphate level in patients that are on dialysis treatment.
  • You must take it with food and stick to the diet prescribed by your doctor.
  • You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
  • Avoid taking any other medicine 1 hour before or 3 hours after taking Sevel.
  • Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.

Brief Description

Indication

Hyperphosphataemia

Administration

Should be taken with food.

Adult Dose

End-Stage Renal Disease Hemodialysis; hyperphosphatemia Initial dose Serum PO4 >9 mg/dL [2.91 mmol/L]: 1600 mg PO q8hr with meals Serum PO4 7.5-9 mg/dL [2.42-2.91 mmol/L]: 1200-1600 mg PO q8hr with meals Serum PO4 5.5-7.5 mg/dL [1.78-2.42 mmol/L]: 800 mg PO q8hr with meals Maintenance dose Serum PO4 >5.5 mg/dL [>1.78 mmol/L]: Increase dose by 400-800 mg per meal Serum PO4 3.5-5.5 mg/dL [1.13-1.78 mmol/L]: Maintain current dose Serum PO4 <3.5 mg/dL [1.13 mmol/L] decrease by 400-800 mg per meal Dosing considerations Titrate dose; increase by 400-800 mg per meal at 2-week intervals; no more than 4 g Switching From Ca-Acetate Substitute 800 mg for 667 mg of Ca-acetate Substitute 1600 for1334 mg of Ca-acetate Substitute 2400 mg for 2001 mg Ca-acetate

Child Dose

Safety and efficacy not established

Contraindication

Hypophosphatemia or bowel obstruction.

Mode of Action

Sevelamer, a polymeric compound, acts by binding to phosphate molecules in the gut, limiting its absorption and thus lowering serum phosphate levels w/o altering Ca, Al, or bicarbonate levels.

Precaution

Patients w/ dysphagia, swallowing disorders, severe GI motility disorders, active inflammatory bowel disease or major GI tract surgery. Pregnancy and lactation. Monitoring Parameters Monitor serum levels of phosphate, Ca, Cl and bicarbonate. Vitamin supplementation due to reduction in vit D, E, K and folic acid absorption. Monitor for signs and symptoms of peritonitis in patients undergoing peritoneal dialysis. Lactation: Not absorbed systemically; not excreted in breast milk

Side Effect

>10% Vomiting (22%),Nausea (20%),Diarrhea (19%),Dyspepsia (16%),Nasopharyngitis (14%),Limb pain (13%),Pruritus (13%),Arthralgia (12%),Bronchitis (11%),Dyspnea (10%),Hypertension (10%) 1-10% Abdominal pain (9%),Constipation (8%),Flatulence (8%),Peritonitis (during peritoneal dialysis: 8%),Hypercalcemia (5-7%) Frequency Not Defined Back pain,Cough,Headache,Pyrexia,Upper respiratory infection,Pruritus,Rash,Intestinal perforation,Fecal impaction,Intestinal obstruction.

Interaction

May decrease absorption of ciprofloxacin, ciclosporin, mycophenolate, tacrolimus and levothyroxine. Sevelamer should be given 3 hr before or 1 hr after taking other drugs to minimise potential pharmacokinetic interaction.

Buy Sevel from Arogga

In Bangladesh, you can get the original Sevel. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Sevel in Bangladesh?

The latest price of Sevel in Bangladesh is 41.03৳. You can buy Sevel at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sevel. Please consult your doctor.
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CONSULT YOUR DOCTOR
Sevel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Sevel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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CONSULT YOUR DOCTOR
It is not known whether Sevel alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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SAFE IF PRESCRIBED
Sevel is safe to use in patients with kidney disease. No dose adjustment of Sevel is recommended. However, regular monitoring of calcium levels is advisable in these patients.
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SAFE IF PRESCRIBED
Sevel is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sevel may not be needed in these patients. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.