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Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sural. Please consult your doctor.
CONSULT YOUR DOCTOR
Sural may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Sural is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Sural may cause side effects which could affect your ability to drive.
Sural occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
CAUTION
Sural should be used with caution in patients with kidney disease. Dose adjustment of Sural may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
CAUTION
Sural should be used with caution in patients with liver disease. Dose adjustment of Sural may be needed. Please consult your doctor.
Medicine Overview of Sural 400mg Tablet
Introduction
Sural is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. Sural is usually given in combination with at least one other tuberculosis medicine. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if...
... Show moreUses of Sural
- Tuberculosis (TB)
Side effects of Sural
Common
- Visual impairment
- Color blindness
How to use Sural
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sural may be taken with or without food, but it is better to take it at a fixed time.
How Sural works
Sural is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.
What if you forget to take Sural?
If you miss a dose of Sural, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Sural is effective at treating tuberculosis when taken together with other antibacterial drugs.
- It has to be taken for several months in order for it work properly (usually 6 months).
- Take it with food to avoid stomach upset.
- It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
- Avoid consuming alcohol while taking this medication.
- Do not stop taking Sural even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.
Brief Description
Indication
Tuberculosis
Administration
Should be taken with food.
Adult Dose
Oral
Primary treatment of pulmonary and extrapulmonary tuberculosis
Adult: Initial 8 wk: 15 mg/kg/day or 30 mg/kg thrice wkly given with isoniazid, rifampicin and pyrazinamide.
For patients with history of antimycobacterial therapy: Initial doses: 25 mg/kg/day for 60 days, thereafter reduce to 15 mg/kg/day.
Child Dose
Tuberculosis
Child: PO 15–25 mg/kg, max 2.5 g q24h
For treatment of drug-resistant tuberculosis: 15-25 mg/kg daily or 50 mg/kg twice wkly.
For congenitally acquired tuberculosis:
Neonates: 15 mg/kg once daily and >1 mth: 15 mg/kg once daily or 30 mg/kg 3 times wkly for 2 mth initial treatment phase.
Renal Dose
Renal impairment: Dose adjustment may be needed as determined by blood levels of ethambutol.
Contraindication
Hypersensitivity; optic neuritis. Lactation.
Mode of Action
Ethambutol interferes with RNA synthesis, causing suppression of Mycobacteria multiplication. It also has bacteriostatic action against M tuberculosis by acting on rapidly growing pathogens in cavity walls and is also effective in slow-growing pathogens. Has some action against atypical opportunistic Mycobacteria e.g. M kansasii, M avium complex (MAC).
Precaution
Impaired pre-treatment visual acuity, elderly, children. Perform liver, kidney and visual acuity tests regularly. Caution when assessing visual acuity in patients with cataracts, DM, recurrent eye inflammation to make sure that changes are not due to the underlying causes.
Lactation: enters breast milk; use with caution (AAP Committee states "compatible with nursing")
Side Effect
Acute gout or hyperuricemia,Abdominal pain,Anaphylaxis,Anorexia,Confusion, disorientation,Fever,Headache,LFT abnormalities,Malaise,Nausea
Optic neuritis; symptoms may include decreased acuity, color blindness or visual defects (usually revrsible with discontinuation, though irreversible blindness has been reported)
Peripheral neuritis,Pruritis,Rash,Vomiting
Pregnancy Category Note
Pregnancy Category: B
Lactation: enters breast milk; use with caution (AAP Committee states "compatible with nursing")
Interaction
Delayed or reduced absorption w/ Al hydroxide.
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