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Targocid
Synovia Pharma PLC.
Generic: Teicoplanin
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Targocid does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Targocid may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Targocid is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Targocid may cause side effects which could affect your ability to drive.
You may have headaches or feel dizzy while being treated with Targocid. If this happens, do not drive.
CAUTION
Targocid should be used with caution in patients with kidney disease. Dose adjustment of Targocid may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Targocid is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Targocid may not be needed in these patients. Please consult your doctor.
Medicine Overview of Targocid 400mg/vial Injection
Introduction
Targocid is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (eg. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood and others. Targocid works by stopping the growth of bacteria and is useful for treating adults as well as children. It is a narrow-spectrum antibiotic that only covers the gram-positive type of bacteria. This medicine is given by drip or by direct injection into a vein, under the supervision of a healthcare professional. It may also be combined with other antibiotics to treat...
... Show moreUses of Targocid
- Severe bacterial infections
Side effects of Targocid
Common
- Injection site reactions (pain, swelling, redness)
- Fever
- Itching
- Skin rash
How to use Targocid
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Targocid works
Targocid is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
Quick Tips
- Targocid is used for treating serious bacterial infections, which cannot be treated with other antibiotics like penicillins and cephalosporins.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- It is given by an injection or drip into a vein or into a muscle.
- Use caution while driving or doing anything that requires concentration as it can cause dizziness and headaches.
- Do not take Targocid if you are pregnant or breastfeeding.
Brief Description
Indication
Gram-positive infection, CAPD-associated peritonitis
Adult Dose
Parenteral Severe Gram-positive infections Adult: Initially, 6 mg/kg on first day, followed by 3 mg/kg/day. Severe infection: 6 mg/kg every 12 hr for the 1st 3 doses followed by 6 mg/kg/day. Doses may be given via IM inj, IV bolus or IV infusion over 30 minutes. Intravenous Prophylaxis of Gram-positive infection in high-risk patients undergoing surgery Adult: 400 mg as single dose at induction of anesth. Continuous ambulatory peritoneal dialysis (CAPD)-associated peritonitis Adult: If the patient is febrile, an initial loading dose of 400 mg may be given. Teicoplanin is added to the dialysis solution at a concentration of 20...
... Show moreChild Dose
Parenteral
Severe Gram-positive infections
Child: Loading dose: 10 mg/kg every 12 hr for 3 doses followed by 6-10 mg/kg/day depending on severity of the infection. Neonates: Loading dose: 16 mg/kg on the 1st day, followed by maintenance doses of 8 mg/kg/day by IV infusion.
Renal Dose
Parenteral
Renal impairment: Usual dose to be given for first 3 days, thereafter adjust dose according to CrCl.
CrCl (ml/min) Dosage Recommendation
40-60 1/2 initial dose given daily or initial dose every 2 days.
<40 1/3 initial dose given daily or initial dose every 3 days.
Intravenous
Renal impairment: Dose adjustment may be required.
Contraindication
Hypersensitivity.
Mode of Action
Glycopeptide antibiotic with spectrum of activity is similar to vancomycin but teicoplanin may be more active in vitro against enterococci and some anaerobic organisms but some coagulase-negative Staphylococci are less sensitive to teicoplanin than to vancomycin.
Precaution
Preexisting renal insufficiency, hypersensitivity to vancomycin. Perform periodic haematological studies, renal, LFT. Pregnancy, lactation.
Side Effect
Fever, chills, allergic reactions, GI disturbances, headache, dizziness, "red-man" syndrome, disturbances in liver enzymes, renal impairment, ototoxicity, blood dyscrasias. Pain, erythema, thrombophloebitis, abscess at site of admin.
Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis.
Interaction
Other nephrotoxic and/or neurotoxic drugs.
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