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Tazocilin 4.5 IV

Injection-(4gm+0.5gm/vial)
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Square Pharmaceuticals PLC.

Generic: Piperacillin + Tazobactam

1 Injection
৳ 911.74
৳ 1003.01
9% OFF
Alternative Brands For Tazocilin 4.5 IV

Medicine Overview of Tazocilin 4.5 IV 4gm+0.5gm/vial Injection

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Introduction

Tazocilin 4.5 IV is a combination of two antibiotics. It is used to treat various types of bacterial infections. It fights against the infection by killing the microorganisms. Tazocilin 4.5 IV is generally administered by a healthcare professional and should not be self-administered. Depending on the severity of your underlying illness, your doctor will decide the precise dose and schedule as per which this injection is to be given. It is strictly advised to be used as per the doctor's prescription. Some of the common side effects of this medicine include nausea, vomiting, diarrhea, and rash. Additionally, you may notice some injection site reactions like pain, swelling, or redness. You should consult your doctor if these side effects do not get better with time and persist for a longer duration. Before using the medicine, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. Your doctor may change the dose or prescribe a different medicine. This medicine is generally considered safe to use during pregnancy and breastfeeding if used under a doctor's supervision.

Uses of Tazocilin 4.5 IV

  • Bacterial infections

Side effects of Tazocilin 4.5 IV

Common
  • Nausea
  • Vomiting
  • Diarrhea
  • Rash
  • Allergic reaction

How to use Tazocilin 4.5 IV

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tazocilin 4.5 IV works

Tazocilin 4.5 IV is a combination of two medicines: Piperacillin and Tazobactum. Piperacillin is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Tazobactum is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Piperacillin against bacteria.

Quick Tips

  • You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Taking probiotics along with Tazocilin 4.5 IV may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
  • Stop taking Tazocilin 4.5 IV and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Brief Description

Indication

Septicaemia, Nosocomial pneumonia

Administration

Reconstitution Reconstitute initially (2.25 g in 10 mL, 4.5 g in 20 mL) w/ water for inj, glucose 5% or NaCl 0.9%, then further dilute to 50-150 mL w/ compatible infusion soln. IV Administration Infusion over 30 min

Adult Dose

Intravenous Nosocomial pneumonia Adult: Each vial contains 4.5 g (piperacillin 4 g and tazobactam 0.5 g): 4.5 g 6 hrly for 5-14 days by infusion over 30 min. When used empirically, combination w/ aminoglycoside or antipseudomonal fluoroquinolone is recommended. Empiric therapy for febrile neutropenic patients Adult: Each vial contains 4.5 g (piperacillin 4 g and tazobactam 0.5 g): 4.5 g 6 hrly for 5-14 days by infusion over 30 min. Complicated intra-abdominal infections Adult: Each vial contains 4.5 g (piperacillin 4 g and tazobactam 0.5 g): 4.5 g 8 hrly for 5-14 days by infusion over 30 min. Complicated urinary tract infections; Skin and soft tissue infections Adult: Each vial contains 4.5 g (piperacillin 4 g and tazobactam 0.5 g): 4.5 g 8 hrly for 5-14 days by infusion over 30 min.

Child Dose

Intravenous Child: Usually <40 kg: 240–300 mg PIP/kg/day 8 hourly Alternatively Nosocomial pneumonia Child: 2-12 yr 90 mg/kg (piperacillin 80 mg/kg and tazobactam 10 mg/kg) 6 hrly for 5-14 days by infusion over 30 min. Max: 4.5 g per dose; >12 yr Same as adult dose. Empiric therapy for febrile neutropenic patients Child: 2-12 yr 90 mg/kg (piperacillin 80 mg/kg and tazobactam 10 mg/kg) 6 hrly for 5-14 days by infusion over 30 min. Max: 4.5 g per dose; >12 yr Same as adult dose. Complicated intra-abdominal infections Child: 2-12 yr 112.5 mg/kg (piperacillin 100 mg and tazobactam 12.5 mg) 8 hrly for 5-14 days by infusion over 30 min. Max: 4.5 g per dose.

Renal Dose

Renal impairment: Haemodialysis patients: 2.25 g 12 hrly; additional dose of 0.75 g after each dialysis session. CAPD: 2.25 g 12 hrly. CrCl (ml/min) Dosage Recommendation <20 2.25 g 8 hrly. 20-40 2.25 g 6 hrly.

Contraindication

Hypersensitivity.

Mode of Action

Piperacillin has an antimicrobial activity against a wide range of gm-ve organisms including K. pneumoniae, P. aeruginosa, Enterobacteriaceae and against gm+ve organisms eg E. faecalis and B. fragilis. Tazobactam is a penicillanic acid sulfone derivative with beta-lactamase inhibitory properties. In combination, tazobactam enhances the activity of piperacillin against beta-lactamase-producing bacteria.

Precaution

Pregnancy and lactation, pseudomembranous colitis. Assess hematopoietic function periodically. Perform periodic electrolyte determinations in patients with low K reserves. Increased risk of fever and rash in patients with cystic fibrosis. Increased risk of bleeding manifestations. Prolonged treatment may increase risk of superinfections. Convulsions or neuromuscular excitability may occur when high doses are used, especially in renally impaired patients. Renal impairment. Lactation: Low concentrations of piperacillin excreted in breast milk; tazobactam unknown; use caution

Side Effect

>10% Diarrhea (7-11%) 1-10% Constipation (1-8%),Headache (1-8%),Insomnia (4-7%),Nausea (2-7%),Fever (2-5%),Oral candidiasis (2-4%),Rash (2-4%),Vomiting (2-4%),Dyspepsia (3%),Pruritus (3%),Pain (2-3%),Hypertension (2%),Leukopenia (1%),Thrombocytopenia (1.4%) <1% Anaphylaxis,Agranulocytosis,Thrombocytopenia,Eosinophilia,Leukopenia,Positive Coombs test,Prolonged PT and PTT,Transient LFT and creatinine elevations.Seizure,Pulmonary edema,Pulmonary embolism

Interaction

Interacts w/ high doses of heparin, oral anticoagulants or other drugs that affect blood coagulation or thrombocyte function. Prolongs the neuromuscular blockade of vecuronium and non-depolarising muscle relaxants. Prolongs half-lives w/ probenecid. Increased risk of methotrexate toxicity.

Buy Tazocilin 4.5 IV from Arogga

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What is the price of Tazocilin 4.5 IV in Bangladesh?

The latest price of Tazocilin 4.5 IV in Bangladesh is 911.74৳. You can buy Tazocilin 4.5 IV at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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SAFE
Consuming alcohol with Tazocilin 4.5 IV does not cause any harmful side effects.
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SAFE IF PRESCRIBED
Tazocilin 4.5 IV is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
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SAFE IF PRESCRIBED
Tazocilin 4.5 IV is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
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CONSULT YOUR DOCTOR
It is not known whether Tazocilin 4.5 IV alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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CAUTION
Tazocilin 4.5 IV should be used with caution in patients with kidney disease. Dose adjustment of Tazocilin 4.5 IV may be needed. Please consult your doctor.
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SAFE IF PRESCRIBED
Tazocilin 4.5 IV is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Tazocilin 4.5 IV may not be needed in these patients. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.