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Tenizide

Tablet-(12.5mg+20mg)
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Unimed Unihealth Pharmaceuticals Ltd.

Generic: Hydrochlorothiazide + Olmesartan Medoxomil

1 Tablet
৳ 7.20
৳ 8
10% OFF

Medicine Overview of Tenizide 12.5mg+20mg Tablet

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Introduction

Tenizide is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure. Tenizide is a medicine used to treat hypertension (high blood pressure). It is a combination of some medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce high blood pressure, thus lowering the chances of any future heart attack and stroke. It is taken with or without food, preferably in the morning to avoid frequent urination at night. Regular monitoring of kidney function and electrolytes is important while using this medicine. This medicine may cause dehydration, so it is better to take plenty of fluids. Dizziness and dry mouth are some other common side effects of this medicine.

Uses of Tenizide

  • Hypertension (high blood pressure)

Side effects of Tenizide

Common
  • Nausea
  • Taste change
  • Upset stomach
  • Diarrhea
  • Headache
  • Dizziness
  • Weakness
  • Electrolyte imbalance
  • Glucose intolerance
  • Increased blood lipid level
  • Increased blood uric acid
  • Decreased blood pressure

How to use Tenizide

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tenizide may be taken with or without food, but it is better to take it at a fixed time.

How Tenizide works

Tenizide is a combination of two medicines: Hydrochlorothiazide and olmesartan which lower blood pressure effectively. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Olmesartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently.

Quick Tips

  • You have been prescribed Tenizide for the treatment of high blood pressure.
  • It can be taken with or without food.
  • Tenizide may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position.
  • Use of Tenizide during pregnancy or breastfeeding is unsafe.
  • It may also decrease the risk of stroke and heart attacks.

Brief Description

Indication

Hypertension, Diabetic nephropathy

Administration

May be taken with or without food.

Adult Dose

Hypertension Initial: 20 mg/12.5 mg PO qDay May increase to 40 mg/25 mg after 2 weeks Hepatic Impairment Dose adjustment not necessary

Child Dose

Safety and efficacy not established

Renal Dose

Renal Impairment CrCl <30 mL/min: Not recommended

Contraindication

Hypersensitivity to olmesartan medoxomil, hydrochlorothiazide or to other sulfonamide-derived drugs. Severe hepatic & renal impairment (CrCl <30 mL/min); cholestasis & biliary obstructive disorders; refractory hypokalemia; hypercalcemia; hyponatraemia, symptomatic hyperuricaemia; anuria. Concomitant use w/ aliskiren in patients w/ DM or renal impairment (GFR <60 mL/min/1.73 m2). Pregnancy (2nd & 3rd trimester) & lactation.

Mode of Action

Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions. Olmesartan is a selective and competitive angiotensin II Type 1 (AT1) receptor antagonist that blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II. As a result, olmesartan relaxes blood vessels, hence lowering BP and increases blood supply and oxygen to the heart.

Precaution

Drugs that act on renin-angiotensin system can cause fetal injury and death when used in 2nd and 3rd trimesters of pregnancy. Olmesartan medoxomil should be discontinued as soon as possible once pregnancy is detected. Symptomatic hypotension may occur in patients who are volume- and/or salt-depleted. May be associated with oliguria, progressive azotaemia, and acute renal failure (rare). Patients with bilateral or unilateral renal artery stenosis may have increased risk of severe hypotension and renal insufficiency. Caution in renal impairment; monitor serum creatinine and potassium levels periodically. Avoid use in severe renal impairment (CrCl< 20 mL/min) and severe hepatic impairment. Caution in patients with aortic or mitral valve stenosis, obstructive hypertrophic cardiomyopathy. Patients with primary aldosteronism may not respond to angiotensin receptor antagonist. Not recommended in lactation. Lactation: discontinue drug or do not nurse

Side Effect

1-10% Olmesartan Dizziness (3%),Headache (1%),Fatigue,Diarrhea (1%),Hyperglycemia (1%),Hypertriglyceridemia (1%),Back pain (1%),Bronchitis (1%),Flu-like symptoms (1%),Pharyngitis (1%),Rhinitis (1%),Sinusitis (1%),URI (1%) Frequency Not Defined Chest pain,Peripheral edema,Rash,Hyperuricemia,Dizziness,Hyperlipidemia,Diarrhea,Hyperuricemia,Hematuria,Hyperglycemia,Upper respiratory infections,Increased transaminases,Gastroenteritis,Dyspepsia,Arthralgia,Arthritis,Myalgia,Back pain,Increased CPK,Hydrochlorothiazide,Anorexia,Epigastric distress,Hypotension,Orthostatic hypotension,Photosensitivity,Anaphylaxis,Anemia,Confusion,Erythema multiforme,Stevens-Johnson syndrome,Exfoliative dermatitis including toxic epidermal necrolysis,Dizziness,Hypokalemia and/or hypomagnesemia,Hyperuricemia,Headache Potentially Fatal: Acute renal failure.

Pregnancy Category Note

Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters)

Interaction

Olmesartan medoxomil: Increased risk of hypotension, hyperkalemia & changes in renal function w/ aliskiren. May result in deterioration of renal function w/ NSAIDs. May attenuate the antihypertensive effect of angiotensin II receptor antagonists. Reduces systemic exposure & peak plasma conc w/ colosevelam HCl. Hydrochlorothiazide: Potentiation of orthostatic hypotension w/ alcohol, barbiturates or narcotics. Antidiabetic drugs. Potentiation effect w/ other antihypertensives. Reduced absorption w/ cholestyramine & colestipol resins. Intensified electrolyte depletion w/ corticosteroid, ACTH. Decreased response to pressor amines (eg norepinephrine). Increased responsiveness to skeletal muscle relaxants (eg tubocurarine). Reduce the renal clearance of lithium.

Buy Tenizide from Arogga

In Bangladesh, you can get the original Tenizide. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Tenizide in Bangladesh?

The latest price of Tenizide in Bangladesh is 7.2৳. You can buy Tenizide at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
Tenizide may cause excessive drowsiness with alcohol.
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CONSULT YOUR DOCTOR
Tenizide is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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SAFE IF PRESCRIBED
Tenizide is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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UNSAFE
Tenizide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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CAUTION
Tenizide should be used with caution in patients with severe kidney disease. Dose adjustment of Tenizide may be needed. Please consult your doctor. Regular monitoring of blood pressure is advisable for dose adjustment.
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CAUTION
Tenizide should be used with caution in patients with liver disease. Dose adjustment of Tenizide may be needed. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.