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Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tiotrop. Please consult your doctor.
CONSULT YOUR DOCTOR
Tiotrop may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Tiotrop is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the baby for dry mouth, constipation, and urinary problems.
Medicine Overview of Tiotrop 18mcg Capsule
Introduction
Tiotrop is an anticholinergic medicine. It is used in the treatment of chronic obstructive pulmonary disease and asthma. Tiotrop is only for the inhalational purpose, so do not swallow the capsule. The first dose is given under medical supervision to prevent the side effects happen during first use. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as...
... Show moreUses of Tiotrop
- Chronic obstructive pulmonary disease (COPD)
- Asthma
Side effects of Tiotrop
Common
- Blurred vision
- Increased heart rate
- Dryness in mouth
- Upper respiratory tract infection
- Constipation
How to use Tiotrop
Rotacaps must not be swallowed. Check the label for directions before use. Place the capsule at the base of rotahaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the rotahaler repeat the process.
How Tiotrop works
Tiotrop is an anticholinergic medication. It works by relaxing the muscles in the airways and widens the airways. This makes breathing easier.
What if you forget to take Tiotrop?
If you miss a dose of Tiotrop, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Tiotrop makes breathing easier for patients with chronic obstructive pulmonary disease (COPD) and asthma.
- This medicine is for inhalation only. The tablet should not be swallowed.
- It should be taken at the same time each day.
- It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
- Take the first dose under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
- Your doctor may monitor your blood potassium level regularly while taking this medication.
- Only small amounts of Tiotrop may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
Brief Description
Indication
Tiotropium is indicated for the long term once daily maintenance treatment of bronchospasm and dyspnoea associated with, chronic obstructive pulmonary disease (COPD), including, chronic bronchitis and emphysema.
Adult Dose
Inhalation
Chronic obstructive pulmonary disease
Adult: As Inhaler: 2 puffs (18mcg) once daily.
As inhalation cap: 1 cap (18 mcg) daily via inhaler device, at the same time each day.
Child Dose
Inhalation
Chronic obstructive pulmonary disease
Child> 12 years: As Inhaler: 2 puffs (18mcg) once daily.
Child> 18 years: As inhalation cap: 1 cap (18 mcg) daily via inhaler device, at the same time each day.
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
<50 Use w/ caution.
Contraindication
Hypersensitivity to atropine and its derivatives (e.g. ipratropium).
Mode of Action
Tiotropium bromide, a long-acting quaternary ammonium antimuscarinic, is structurally related to ipratropium. It is a nonselective competitive antagonist of muscarinic (M1-M5) receptors and causes bronchodilation by inhibiting the actions of acetylcholine and other cholinergic stimuli at M3 receptors in the smooth muscle of the respiratory tract.
Precaution
Not intended for use as initial treatment for acute bronchospasm and as monotherapy for asthma. Patient w/ narrow-angle glaucoma, prostatic hyperplasia/bladder neck obstruction, cystic fibrosis. History of MI (<6 mth), or unstable or life threatening cardiac arrhythmia w/in the past yr. Moderate to severe renal impairment (CrCl ≤50 mL/min). Pregnancy and lactation. Patient Counselling This drug may cause dizziness and blurred vision, if affected, do not drive or operate machinery. Monitoring Parameters Monitor pulmonary function.
Side Effect
>10%
Upper respiratory tract infection (41%),Dry mouth (16%),Sinusitis (11%)
1-10%
Abdominal pain,Allergic reaction,Angina pectoris (including aggravated angina pectoris),Cataract,Chest pain (nonspecific),Constipation,Depression,Dyspepsia,Dysphonia,Edema,Epistaxis,Gastroesophageal reflux,Herpes zoster,Hypercholesterolemia,Hyperglycemia,Infection,Laryngitis,Leg pain,Moniliasis,Myalgia,Paresthesia,Pharyngitis,Rash,Rhinitis,Skeletal pain,Stomatitis (including ulcerative stomatitis),Urinary tract infection,Vomiting
<1%
Angioedema,Fibrillation,Supraventricular tachycardia,Urinary retention
Interaction
Other anticholinergic agents.
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