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Tobrel
Healthcare Pharmaceuticals Ltd.
Generic: Tobramycin Eye prep
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Tobrel is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Tobrel is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
SAFE
Tobrel does not usually affect your ability to drive.
Medicine Overview of Tobrel 0.30% Eye Drop
Introduction
Tobrel is an antibiotic used to treat bacterial infections of the eye (eg. conjunctivitis) and the eyelids (e.g. blepharitis). It may also help to prevent an infection after an eye injury or surgery. Tobrel stops the growth of bacteria and thereby helps to cure the underlying infection. Follow your doctor's instructions precisely for administering this medicine in the eye. Wait for at least 5 minutes before applying any other eye medication. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if...
... Show moreUses of Tobrel
- Bacterial eye infections
Side effects of Tobrel
Common
- Eye irritation
- Burning sensation
How to use Tobrel
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Tobrel works
Tobrel is an antibiotic. It stops bacterial growth in the eye by preventing synthesis of essential proteins required by bacteria to carry out vital functions. This treats your eye infection.
What if you forget to take Tobrel?
If you miss a dose of Tobrel, please consult your doctor.
Quick Tips
- Your doctor has prescribed Tobrel to treat bacterial infections of the eye.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Tobrel may cause damage to cornea on long-term use.
- Apply pressure on the corner of the eye (close to the nose) for about 1 minute immediately after instilling the drop.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- Stinging sensation may occur for 1-2 mins. Notify your doctor if it persists for longer.
- Make sure to use within 4 weeks of opening the bottle.
Brief Description
Indication
Ocular infection, bacterial eye infection
Adult Dose
Ophthalmic
Ocular infections
Adult: As eye drop: Mild to moderate infections: Instill 1-2 drops into affected eye every 4 hr.
Severe infections: Instill 2 drops into affected eye every 30-60 minutes initially until improvement, reduce treatment frequency before discontinuation.
As eye ointment: Mild to moderate infections: Apply a half-inch ribbon bid-tid into affected eye.
Severe infections: Apply a half-inch ribbon into the affected eye every 3-4 hr until improvement, reduce treatment frequency before discontinuation.
Child Dose
Ophthalmic
Ocular infections
Child: >1 yr: As eye drop: Mild to moderate infections: Instill 1-2 drops into affected eye every 4 hr.
Severe infections: Instill 2 drops into affected eye every 30-60 minutes initially until improvement, reduce treatment frequency before discontinuation.
As eye ointment: Mild to moderate infections: Apply a half-inch ribbon bid-tid into affected eye.
Severe infections: Apply a half-inch ribbon into the affected eye every 3-4 hr until improvement, reduce treatment frequency before discontinuation.
Contraindication
This eye drop is contraindicated in epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella and other viral disease of the cornea and conjunctiva.It is contraindicated in mycobacterial infections of the eye caused by acid-fast bacilli such as Mycobacterium tuberculosis, Mycobacterium leprae, or Mycobacterium avium. Fungal diseases of eye, untreated purulent infection of the eye. Hypersensitivity to any component of the medication.
Mode of Action
Tobramycin acts by binding to 30S ribosomal subunits thus interfering with bacterial protein synthesis. It is active against many aerobic gram-negative bacteria and some aerobic gram-positive bacteria but inactive against Chlamydia, fungi, viruses, and most anaerobic bacteria.
Precaution
May result in overgrowth of nonsusceptible organisms, including fungi. Patient Counselling This drug may cause temporary blurred vision, if affected, do not drive or operate machinery. Contact lens wear is not recommended during treatment
Lactation: Unknown whether drug is safe for nursing infants; discontinue, or do not nurse
Side Effect
Localized ocular toxicity and hypersensitivity, including increased lacrimation, itching and edema of eyelid, and conjunctival erythema (<3%)
Sensitivity reaction, punctate keratitis
Interaction
Increased nephrotoxicity or ototoxicity with etacrynic acid, furosemide, other aminoglycosides, cefalotin, cisplatin, vancomycin, piperacillin, ciclosporin, amphotericin B. Decrease serum tobramycin levels with miconazole.
Potentially Fatal: Increased neuromuscular-blocking activity with magnesium and other neuromuscular-blocking agents.
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