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Trileptal

Syrup-(60mg/ml)
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Nevian Lifescience PLC

Generic: Oxcarbazepine

1 x 100ml bot
৳ 964.80
৳ 1072
10% OFF

Medicine Overview of Trileptal 60mg/ml Syrup

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Introduction

Trileptal is a prescription medicine used to treat and prevent epilepsy (seizures). However, it cannot cure epilepsy and will only work to prevent seizures for as long as you continue to take the medicine. Trileptal may be used alone or in combination with other medicines. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. You can take this medicine with or without food but take it at the same time each day to get the most benefit. It usually takes a couple of weeks to work. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may trigger seizures and, if you stop, your condition may get worse. It should never be stopped suddenly. The most common side effects of this medicine include nausea, vomiting, feeling dizzy, tired or drowsy, and unsteadiness. Most of these are not serious. Keep taking the medicine but talk to your doctor if these side effects bother you or do not go away. However, if you notice a skin rash or redness, tell your doctor straight away. It could develop into a life-threatening skin condition called Stevens-Johnson syndrome. Long-term treatment with this medicine can cause osteoporosis (reduced bone mass) and increase your risk of breaking a bone. Anticonvulsants like this medicine may cause suicidal thoughts and behaviors. If your mood becomes depressed, tell your doctor. This medicine may not be suitable for everybody. Before using it, tell your doctor if you have ever had heart problems, kidney or liver disease, difficulty urinating, depression or suicidal thoughts. Many other medicines can interfere with it and some should not be taken together so tell your doctor all the medicines you are taking to make sure it is safe. If you are pregnant, do not start or stop taking this medicine without asking your doctor. Drinking alcohol should be avoided as it can increase some of the side effects and can also increase your risk of seizures. You may need frequent blood tests to help your doctor make sure you are taking the right dose both before you start and while you are using it.

Uses of Trileptal

  • Epilepsy/Seizures

Side effects of Trileptal

Common
  • Headache
  • Nausea
  • Vomiting
  • Double vision
  • Fatigue
  • Dizziness
  • Impaired coordination
  • Nystagmus (involuntary eye movement)
  • Tremor
  • Abnormal vision
  • Altered walking
  • Sleepiness

How to use Trileptal

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trileptal may be taken with or without food, but it is better to take it at a fixed time.

How Trileptal works

Trileptal is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

What if you forget to take Trileptal?

If you miss a dose of Trileptal, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It may increase the risk of low sodium levels in the blood. Inform your doctor if you develop difficulty concentrating, memory problems, confusion, weakness, and unsteadiness.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Brief Description

Indication

Partial seizures, Generalised tonic-clonic seizures

Administration

May be taken with or without food.

Adult Dose

Oral Partial seizures Adult: Adjunctive treatment 300 mg PO q12hr initially; may increase at weekly intervals by 600 mg/day up to 1200 mg/day Monotherapy (if converting from other AED) Initial: 300 mg PO q12hr; increase by 600 mg/day qWeek up to 2400 mg/day Reduce and withdraw concomitant antiepileptic drugs (AEDs) over 3-6 weeks while reaching maximum oxcarbazepine dose in 2-4 weeks Monotherapy (if AED naive) Initial: 300 mg PO q12hr; increase by 300 mg/day q3Day to 1200 mg/day divided q12hr Diabetic Neuropathy 150-300 mg/day PO initially; may increase to 900-1200 mg/day (general recommendation) Neuralgia/Neuropathy 300 mg PO q8-12hr initially; may adjust dose to 400-2000 mg divided q8-12hr (maximum tolerated or effective dose) Hepatic impairment Mild to moderate: No dose adjustment required Severe: Unknown if dosage adjustment necessary

Child Dose

Partial Seizures (Adjunctive Treatment) (age 2-4 years) Initial: 8-10 mg/kg/day PO divided q12hr; not to exceed 600 mg/day <20 kg: May start with16-20 mg/kg/day; may titrate to higher dose over 2-4 weeks; not to exceed 60 mg/kg/day (age 4-16 years) Initial: 8-10 mg/kg/day PO divided q12hr; not to exceed 600 mg/day Target maintenance dose: May titrate to higher dose over 2 weeks to reach the following dosage ranges 20-29 kg: 450 mg PO q12hr 29.1-39 kg: 600 mg PO q12hr >39 kg: 900 mg PO q12hr Partial Seizures (Monotherapy) (age 4-16 years) AED: Initial, 8-10 mg/kg/day PO divided q12hr; may increase qWeek by maximum increment of 10 mg/kg/day AED-naive: Initial 8-10 mg/kg/day PO divided q12hr; may increase q3Days by 5 mg/kg/day Target maintenance: Weight-based dosing may be as high as 2100 mg/day for >60 kg 20-24.99 kg: 600-900 mg/day 25-34.99 kg: 900-1200 mg/day 35-44.99 kg: 900-1500 mg/day 45-49.99 kg: 1200-1500 mg/day 50-59.99 kg: 1200-1800 mg/day 60-69.99 kg: 1200-2100 mg/day 70 kg: 1500-2100 mg/day

Renal Dose

Renal impairment CrCl <30 mL/min: Decrease initial dose by 50%, titrate up slowly

Contraindication

Hypersensitivity. Lactation.

Mode of Action

Oxcarbazepine blocks voltage-sensitive sodium channels, which inhibits repetitive firing, stabilises hyperexcited neuronal membranes and decreases release of synaptic impulses. These effects may prevent the spread of epileptic seizures.

Precaution

Patient carrying the HLA-B*1502 allele. Avoid abrupt withdrawal. Severe renal and hepatic impairment. Pregnancy. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor seizure frequency, serum Na, symptoms of CNS depression, hypersensitivity reactions, serum levels of concomitant antiepileptic drugs during titration; periodic thyroid function test and CBC. Lactation: Oxcarbazepine and its active metabolite (MHD) are excreted in human milk; milk-to-plasma concentration ratio of 0.5 was found for both Because of the potential for serious adverse reactions in nursing infants, a decision should be made as to whether a mother should discontinue nursing or whether she should discontinue use of the drug, taking into account the drug's importance to the mother

Side Effect

>10% Dizziness (30-50%),Diplopia (30-50%),Headache (26-30%),Nausea/vomiting (26-30%),Nystagmus (26-30%),Somnolence (26-30%),Ataxia (10-30%),Abnormal gait (16-20%),Tremor (16-20%),Abdominal pain (11-15%),Fatigue (11-15%),Vertigo (11-15%),Vision abnormalities (11-15%) 1-10% Dyspepsia (5-6%),Rash (4%),Insomnia (2-4%),Abnormal thinking (<4%),Hyponatremia (1-3%),Muscle weakness (1-2%),Hypotension (<2%),Speech disorder (1%),Asthenia

Interaction

Reduced serum levels with carbamazepine, phenobarbitone, phenytoin, valproic acid. May reduce levels/effects of CYP3A4 substrates (e.g. benzodiazepines, calcium channel blockers, clarithromycin, ciclosporin, erythromycin, oestrogens, mirtazapine, nateglinide, nefazodone, nevirapine, protease inhibitors, tacrolimus, venlafaxine). May reduce efficacy of oral contraceptives. May reduce levels/effects of maraviroc. May increase levels of phenobarbitone, phenytoin.

Buy Trileptal from Arogga

In Bangladesh, you can get the original Trileptal. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Trileptal in Bangladesh?

The latest price of Trileptal in Bangladesh is 964.8৳. You can buy Trileptal at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
Trileptal may cause excessive drowsiness with alcohol.
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CONSULT YOUR DOCTOR
Trileptal may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Trileptal is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Baby should be monitored for excessive sleepiness and weight gain.
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UNSAFE
Trileptal may cause side effects which could affect your ability to drive. Trileptal may make you feel sleepy or dizzy, or may cause blurred vision, lack of muscle coordination, especially when starting treatment or increasing the dose. This may affect your driving ability.
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CAUTION
Trileptal should be used with caution in patients with kidney disease. Dose adjustment of Trileptal may be needed. Please consult your doctor.
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CAUTION
Trileptal should be used with caution in patients with severe liver disease. Dose adjustment of Trileptal may be needed. Please consult your doctor. Dose adjustment is not recommended in patients with mild to moderate liver disease.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.