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Urbifen 50
General Pharmaceuticals Ltd.
Generic: Flurbiprofen
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Urbifen 50 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Urbifen 50 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medicine Overview of Urbifen 50mg Tablet
Introduction
Urbifen 50 is a pain relieving medicine. It is used to treat pain, swelling, and stiffness caused by conditions such as osteoarthritis and rheumatoid arthritis. Urbifen 50 is only meant for external use and should be used strictly as advised by your doctor. A thin layer of the medicine should be massaged into the affected areas with clean and dry hands. Avoid getting in contact with your eyes, nose, or mouth and avoid applying it on wounded or damaged skin. In case of accidental contact, you should rinse it thoroughly with plenty of water. It is usually safe with little...
... Show moreUses of Urbifen 50 Gel
- Pain relief
Side effects of Urbifen 50 Gel
Common
- No common side effects seen
How to use Urbifen 50 Gel
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
How Urbifen 50 Gel works
Urbifen 50 is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
Quick Tips
- You have been prescribed Urbifen 50 to relieve pain and inflammation.
Brief Description
Indication
Dysmenorrhoea, Sore throat, Ocular inflammation, Pain and inflammation associated w/ musculoskeletal and joint disorders, Prophylaxis of miosis during ocular surgery
Administration
Should be taken with food.
Adult Dose
Oral
Pain and inflammation
Adult: 150-200 mg daily in divided doses, increased to 300 mg daily in acute or severe conditions if necessary.
Dysmenorrhoea
Adult: Initially, 100 mg followed by 50-100 mg 4-6 hrly. Max: 300 mg daily.
Rheumatoid Arthritis, Osteoarthritis
200-300 mg/day divided q6-12hr PO, not to exceed 100 mg/dose or 300 mg/day
Child Dose
<12 years: Not recommended
Renal Dose
Renal Impairment
Severe Impairment: Not recommended
Contraindication
Peptic ulcer, GI haemorrhage, asthma, bronchospasm, rhinitis, angioedema, hypersensitivity; aspirin intolerance; pregnancy (3rd trimester); lactation.
Mode of Action
Flurbiprofen inhibits prostaglandin synthesis by decreasing the activity of cyclooxygenase resulting in reduced prostaglandin levels. It is also a potent inhibitor of platelet aggregation.
Precaution
Patients w/ known CV disease or risk factors for CV disease, fluid retention. Hepatic and renal impairment. Lactation.
Lactation: excreted in breast milk; not recommended
Side Effect
Oedema, abdominal pain, constipation, diarrhoea, dyspepsia/heartburn, liver enzyme elevations, flatulence, nausea, vomiting, wt change, headache, nervousness, CNS stimulation (e.g. anxiety), CNS inhibition (e.g. somnolence), rhinitis, vision changes, dizziness/vertigo, tinnitus, signs and symptoms of UTI, rash. Ocular hyperaemia, eye irritation, fibrosis, miosis, mydriasis.
Potentially Fatal: GI bleeding, ulceration and perforation, jaundice, fulminant hepatitis, liver necrosis, hepatic failure.
Pregnancy Category Note
Pregnancy Category: C; avoid in late pregnancy
Lactation: excreted in breast milk; not recommended
Interaction
Reduced antihypertensive effect of ACE inhibitors, angiotensin II receptor antagonists and ?-blockers. Slight reduction in blood glucose concentration in patients w/ DM receiving certain antidiabetic agents (e.g. glyburide, metformin). Reduced diuretic effect of furosemide and thiazides. May increase toxicity of lithium and methotrexate. May increase risk of bleeding w/ antiplatelets, anticoagulants, SSRIs, corticosteroids.
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