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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Venlaf.
CONSULT YOUR DOCTOR
Venlaf may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Venlaf is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for excessive sleepiness and adequate weight gain.
UNSAFE
Venlaf may cause side effects which could affect your ability to drive.
As side effects of Venlaf are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
CAUTION
Venlaf should be used with caution in patients with kidney disease. Dose adjustment of Venlaf may be needed. Please consult your doctor.
CAUTION
Venlaf should be used with caution in patients with liver disease. Dose adjustment of Venlaf may be needed. Please consult your doctor.
Medicine Overview of Venlaf 25mg Tablet
Introduction
Venlaf is a prescription medicine used in the treatment of depression and anxiety disorder. It alters the chemicals in the brain that cause symptoms of anxiety such as irritability, restlessness, lack of concentration, fatigue, sweating, increased heart rate and unwanted or racing thoughts. Venlaf should be taken with food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It...
... Show moreUses of Venlaf
- Depression
- Anxiety disorder
Side effects of Venlaf
Common
- Nausea
- Vomiting
- Dizziness
- Insomnia (difficulty in sleeping)
- Decreased appetite
- Anxiety
- Constipation
- Increased sweating
- Sexual dysfunction
How to use Venlaf
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Venlaf is to be taken with food.
How Venlaf works
Venlaf works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.
What if you forget to take Venlaf?
If you miss a dose of Venlaf, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Veniz XR 75 Capsule helps in treating depression and anxiety.
- It may also be used to treat nerve pain from diabetes and some other forms of chronic pain.
- It may take 2 to 4 weeks for Veniz XR 75 Capsule to start working. Keep taking it as prescribed.
- It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Veniz XR 75 Capsule as it may cause excessive drowsiness and increase the risk of liver damage.
- It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking the medication suddenly without talking to your doctor.
Brief Description
Indication
Depression, Anxiety, Panic disorder, Social anxiety disorder
Administration
Take with food
Adult Dose
Oral Depression Adult: Conventional tab: Initially, 75 mg/day in 2 or 3 divided doses, may increase in increments of up to 75 mg/day at intervals of 4 days or more. Max: 375 mg/day. Extended-release: Initially, 37.5-75 mg once daily; in patients initiated at 37.5 mg once daily, may increase to 75 mg once daily after 4-7 days; dose may then be increased in increments of up to 75 mg/day at intervals of 4 days or more. Max: 225 mg/day. Panic disorder Adult: Extended-release: Initially, 37.5 mg once daily for a wk, may increase to 75 mg once daily after 7...
... Show moreChild Dose
Attention Deficit Disorder
40 kg: 12.5 mg/day PO initially; increase by 25 mg/week; not to exceed 75 mg/day divided three times daily
Depression
Children: 37.5 mg/day PO initially
Adolescents: 37.5-75 mg/day PO initially
Maintenance: Children, 75-150 mg/day; adolescents, 150-300 mg/day
Renal Dose
Renal impairment: GFR <30 mL/min and patient requiring haemodialysis: Reduce dose by 50%.
Contraindication
Uncontrolled hypertension; high risk of serious ventricular arrhythmia.
Mode of Action
Venlafaxine and its active metabolite O-desmethylvenlafaxine selectively inhibit the neuronal reuptake of serotonin, norepinephrine and to a lesser extent dopamine. It has minimal affinity for muscarinic, histamine, or ?1-adrenergic receptors. It appears to be as effective as standard antidepressants but w/ a lower incidence of anticholinergic, sedative and CV side effects.
Precaution
History of MI or unstable cardiac disease, seizure; hypomania or mania, increased intraocular pressure or at risk of acute narrow-angle glaucoma, at risk of bleeding. Renal and hepatic impairment. Gradual dose reduction is recommended rather than abrupt withdrawal. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor BP and heart rate regularly, cholesterol, mental status for depression. Closely observe for clinical worsening, suicidality and unusual changes in behaviour. Monitor for emergence of serotonin syndrome. In short-term studies, antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults (<24...
... Show moreSide Effect
>10%
Headache (25-38%),Nausea (21-58%),Insomnia (15-24%),Asthenia (16-20%),Dizziness (11-24%),Ejaculation disorder (2-19%),Somnolence (12-26%),Dry mouth (12-22%),Diaphoresis (7-19%),Anorexia (15-17%),Nervousness (17-26%),Anorgasmia (5-13%)
1-10%
Weight loss (1-6%),Abnormal vision (4-6%),Hypertension (2-5%),Impotence (4-6%),Paresthesia (2-3%),Tremor (1-10%),Vasodilation (2-6%),Vomiting (3-8%),Weight gain (2%),Flatulence (3-4%),Pruritus (1%),Yawning (3-8%),Dyspepsia (5-7%),Twitching (1-3%),Mydriasis (2%)
<1%
Angioedema,Agranulocytosis,Anemia,Anuria,Aneurism,Bacteremia,Myasthenia,Syncope,Suicide ideation/attempt
Potentially Fatal: Blood dyscrasias, Stevens-Johnson syndrome, hepatitis.
Interaction
Increased risk of serotonin syndrome w/ TCA, SSRI, SNRI, lithium, sibutramine, tramadol. May increase serum levels w/ CYP3A4 inhibitors (e.g. ketoconazole, atazanavir, clarithromycin). May increase serum levels of haloperidol. May decrease serum levels of indinavir. May increase bleeding risk w/ aspirin, NSAIDs, warfarin and other anticoagulants.
Potentially Fatal: Increased risk of serotonin syndrome w/ MAOIs, linezolid and methylene blue.
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