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Xonimide

Capsule-(50mg)
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Beacon Pharmaceuticals PLC

Generic: Zonisamide

1 Capsule
৳ 13.50
৳ 15
10% OFF

Medicine Overview of Xonimide 50mg Capsule

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Introduction

Xonimide is an anti-epileptic medicine used to treat seizures in epilepsy. It can be used by itself to treat adults or along with other medicines to treat adults and children. It helps to prevent seizures affecting a part or whole of the brain. Xonimide suppresses the abnormal electrical activity in the brain. You can take it with or without food but try to take it at the same time each day to get the most benefit. The dose will depend on your condition and how you respond to the medicine. Your doctor will advise the right dose for you. You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. It may take several months to come off it safely. It is advised not to change the brand of medication without doctor consultation, and always keep a stock of medicine with you. Very few people taking it have any serious problems but the most common side effects of this medicine include dizziness, loss of appetite, memory loss, drowsiness, and impaired concentration. You may also experience altered walking, impaired coordination, and unusual anger. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. Most do not need medical attention, but some of them can be serious. Let your doctor know if you have any symptoms as there may be ways of preventing or reducing them. A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse. Please do not take this medicine if you are allergic to sulfa medicines. Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested often while taking this medicine.

Uses of Xonimide

  • Epilepsy/Seizures

Side effects of Xonimide

Common
  • Dizziness
  • Loss of appetite
  • Memory impairment
  • Drowsiness
  • Impaired concentration
  • Altered walking
  • Impaired coordination
  • Anger

How to use Xonimide

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xonimide may be taken with or without food, but it is better to take it at a fixed time.

How Xonimide works

Xonimide is an antiepileptic medication. It prevents seizures in patients with epilepsy by suppressing the abnormal and excessive activity of the nerve cells in the brain.

What if you forget to take Xonimide?

If you miss a dose of Xonimide, skip it and continue with your normal schedule. Do not double the dose.

Quick Tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
  • Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Drink plenty of water while taking Xonimide to reduce the risk of kidney stones and heat stroke. Inform your doctor if you have sudden pain in your stomach, pain on urinating, or if you find blood in your urine.
  • It may cause loss of appetite and weight. Monitor your weight regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Brief Description

Indication

Adjunct in partial seizures, Monotherapy for partial seizures with or without secondary generalisation

Administration

May be taken with or without food.

Adult Dose

Oral Adjunct in partial seizures Adult: Initially, 50 mg daily in 2 divided doses, increase to 100 mg daily after 1 wk. Thereafter, may further increase dose at wkly intervals in increments of up to 100 mg. Usual maintenance dose: 300-500 mg daily, some patients may respond to lower doses. Monotherapy for partial seizures with or without secondary generalisation Adult: In patients w/ newly diagnosed epilepsy: Initially, 100 mg once daily, increase to 200 mg once daily after 2 wk. May further increase by increments of 100 mg at intervals of at least 2 wk. Usual maintenance dose: 300 mg once daily, up to 500 mg daily. Hepatic impairment: Mild to moderate: Slower dosage titration may be needed. Severe: Not recommended.

Child Dose

Oral Adjunct in partial seizures Child: >6 yr Initially, 1 mg/kg once daily for 1 wk, may increase by increments of 1 mg/kg at wkly interval. Usual maintenance dose: 20-55 kg: 6-8 mg/kg once daily; >55 kg: 300-500 mg once daily, some may respond to lower dose.

Renal Dose

Renal impairment: GFR ?50 mL/min: Slower dosage titration may be needed. GFR <50 mL/min: Not recommended.

Contraindication

Hypersensitivity to zonisamide or sulfonamides

Mode of Action

Zonisamide is a benzisoxazole derivative anticonvulsant containing sulfonamide. It may act on voltage sensitive Na and Ca channels, thereby affecting neuronal firing, hence reducing the spread of seizure discharges. It may modulate GABA-mediated neuronal inhibition.

Precaution

Patient at risk of nephrolithiasis. Avoid abrupt withdrawal. Renal or hepatic impairment. Childn. Pregnancy and lactation. Patient Counselling Increase fluid intake (i.e. 6-8 glasses of water/day) to reduce risk of renal stone. This drug may cause drowsiness or difficulty w/ concentration, if affected, do not drive or operate machinery. Increase in suicidal ideation may occur with use. Monitoring Parameters Monitor metabolic profile specifically BUN, serum creatinine; serum bicarbonate, body temp, suicidality, decreased sweating. Lactation: Unknown; avoid during breastfeeding

Side Effect

>10% Somnolence (17%) Anorexia (13%) Dizziness (13%) 1-10% Headache (10%) Nausea (9%) Agitation (9%) Abdominal pain (6%) Ataxia (6%) Confusion (6%) Depression (6%) Diplopia (6%) Insomnia (6%) Diarrhea (5%) Speech disorder (5%) Flu-like symptoms (4%) Kidney stones (4%) Nystagmus (4%) Paresthesia (4%) Dysgeusia (3%) Weight loss (3%) Anxiety (3%) Rash (3%) Constipation (2%) Rhinitis (2%) Xerostomia (2%)

Interaction

Reduced plasma concentration w/ phenytoin, phenobarbital, carbamazepine. Increased risk of metabolic acidosis w/ carbonic anhydrase inhibitors (e.g. acetazolamide).

Buy Xonimide from Arogga

In Bangladesh, you can get the original Xonimide. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Xonimide in Bangladesh?

The latest price of Xonimide in Bangladesh is 13.5৳. You can buy Xonimide at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
Xonimide may cause excessive drowsiness with alcohol.
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CONSULT YOUR DOCTOR
Xonimide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Xonimide is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
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UNSAFE
Xonimide may cause side effects which could affect your ability to drive. As Xonimide may affect your concentration, ability to react/respond, and may make you feel sleepy, particularly at the beginning of your treatment or after your dose is increased.
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CAUTION
Xonimide should be used with caution in patients with severe kidney disease. Dose adjustment of Xonimide may be needed. Please consult your doctor.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Xonimide in patients with liver disease. Please consult your doctor. Use of Xonimide is not recommended in patients with severe liver disease.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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