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Safety Advices
বাংলা
English
UNSAFE
Zatral may cause excessive drowsiness with alcohol.
SAFE IF PRESCRIBED
Zatral is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CONSULT YOUR DOCTOR
Information regarding the use of Zatral during breastfeeding is not available. Please consult your doctor.
UNSAFE
Zatral may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Zatral should be used with caution in patients with kidney disease. Dose adjustment of Zatral may be needed. Please consult your doctor.
CAUTION
Zatral should be used with caution in patients with liver disease. Dose adjustment of Zatral may be needed. Please consult your doctor.
Use of Zatral is not recommended in patients with moderate and severe liver disease.
Medicine Overview of Zatral 10mg Tablet
Introduction
Zatral is an alpha adrenergic antagonist that is used in the treatment of benign prostatic hyperplasia. It helps to relieve symptoms like difficulty in passing urine. However, it does not decrease the size of the prostate. Zatral is advised to take it in a dose and duration as per prescription. It should be taken with food, but take at the same time regularly. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment...
... Show moreUses of Zatral
- Benign prostatic hyperplasia
Side effects of Zatral
Common
- Dizziness
- Headache
- Tiredness
How to use Zatral
Use it as advised by your doctor or check the label for directions before use. Zatral is to be taken with food.
How Zatral works
Zatral is an alpha blocker. It works by relaxing muscle around the bladder exit and prostate gland so urine is passed more easily.
What if you forget to take Zatral?
If you miss a dose of Zatral, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Flotral 10 Tablet PR helps in relieving the symptoms of enlarged prostate. It does not decrease the size of the prostate.
- Flotral 10 Tablet PR must be taken with food.
- You will feel better within hours or days of starting the treatment. Full effect is usually seen within 2 weeks.
- Flotral 10 Tablet PR may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Flotral 10 Tablet PR.
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Brief Description
Indication
Oral
Benign prostatic hyperplasia
Adult: 2.5 mg tid. Max: 10 mg/day. 1st dose should be given before bedtime. Extended-release: 10 mg once daily.
Elderly: Initially, 2.5 mg bid. Acute urinary retention: Extended-release: 10 mg once daily to be taken from 1st day of catheterisation. Duration: 3-4 days.
Hepatic impairment: Mild to moderate: Initially, 2.5 mg daily, may increase to 2.5 mg bid according to response. Severe: Contraindicated.
Administration
Additive effect on QT interval prolongation when used w/ QT-prolonging drugs. Concomitant admin w/ other ?1-adrenergic blocking agents, atenolol or diltiazem may result in additive CV effects. Increased plasma alfuzosin concentrations w/ cimetidine.
Potentially Fatal: Concurrent use w/ potent CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir) increase plasma alfuzosin levels.
Adult Dose
Elderly; hypertension; coronary insufficiency; angina (discontinue); renal or hepatic impairment. Monitor BP regularly. May affect ability to drive or operate machinery.
Renal Dose
Alfuzosin is a quinazoline derivative which exhibits selectivity for alpha1-adrenergic receptors in the lower urinary tract. Blockade of these adrenoreceptors causes relaxation of smooth muscle in the bladder neck and prostate, resulting in improvement in urine flow and a reduction in symptoms of benign prostatic hyperplasia (BPH).
Mode of Action
Administration Should be taken with food. Swallow whole.
Extended-Release: Should be taken with food. Take immediately after the same meal each day. Swallow whole, do not chew/crush.
Precaution
Benign prostatic hyperplasia (BPH)
Side Effect
Renal Impairment Initially, 2.5 mg bid. Adjust dose according to response.
Pregnancy Category Note
1-10%
Abdominal pain (1-2%),Back pain (1-2%),Brochitis (1-2%),Constipation (1-2%),Dizziness (5.7%),Dyspepsia (1-2%),Fatigue (2.7%),Headache (3%),Impotence (1-2%),Nausea (1-2%),Pharyngitis (1-2%),URT infection (3%),Sinusitis (1-2%),Upper respiratory infection (3%)
Interaction
Severe hepatic impairment; history of postural hypotension and micturition syncope; intestinal occlusion; severe renal insufficiency; lactation.
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