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Zox 500
Square Pharmaceuticals PLC.
Generic: Nitazoxanide
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zox 500. Please consult your doctor.
SAFE IF PRESCRIBED
Zox 500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CAUTION
Zox 500 should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
If you are taking Zox 500, monitor the baby for diarrhea.
UNSAFE
Zox 500 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CONSULT YOUR DOCTOR
There is limited information available on the use of Zox 500 in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Zox 500 in patients with liver disease. Please consult your doctor.
Medicine Overview of Zox 500mg Tablet
Introduction
Zox 500 is an antiparasitic medication, used in the treatment of diarrhea and worm infections. It inhibits the growth of the parasite and thus treats your infection. Zox 500 should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. Some people may experience headache, nausea, fever, hair loss and vomiting...
... Show moreUses of Zox 500
- Diarrhea
- Worm infections
Side effects of Zox 500
Common
- Headache
- Nausea
- Fever
- Hair loss
- Vomiting
- Abnormal liver function tests
- Dizziness
- Abdominal pain
- Vertigo
How to use Zox 500
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zox 500 is to be taken with food.
How Zox 500 works
Nitazoxanide is an antiparasitic medication. It inhibits the production of certain chemicals and substances essential for energy metabolism and growth of the parasite.
Quick Tips
- You have been prescribed Zox 500 to treat a variety of parasitic worm infections.
- It should be taken with food.
- If you are unable to swallow the whole tablet, it may be crushed or chewed and swallowed with a full glass of water.
- It can be harmful to an unborn baby. Do not take it during pregnancy or breastfeeding. Use birth control measures to prevent pregnancy while taking Zox 500.
- Your doctor may monitor your blood counts and liver function before you start taking this medicine and regularly throughout your treatment.
- Avoid being near people who are sick or have infections. Inform your doctor if you develop signs of infection.
- Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.
Brief Description
Indication
Giardiasis, Cryptosporidiosis
Administration
Should be taken with food.
Adult Dose
Oral
Giardiasis; Cryptosporidiosis
Adult: 500 mg every 12 hr for 3 days.
Child Dose
Oral
Giardiasis; Cryptosporidiosis
Child:
1-3 yr: 100 mg(5 ml) every 12 hr;
4-11 yr: 200 mg(10ml) every 12 hr;
>12 yr: 500 mg every 12 hr.
All doses to be taken for 3 days.
Contraindication
Hypersensitivity.
Mode of Action
Nitazoxanide is an antiprotozoal agent. Both nitazoxanide and its active metabolite (tizoxanide) interfere with the pyruvate:ferredoxin 2-oxidoreductase (PFOR) enzyme-dependent electron transfer reaction which is essential to anaerobic metabolism in susceptible organisms.
Precaution
Renal and hepatic impairment. Pregnancy and lactation. Children <1 yr.
Side Effect
1-10%
Headache (1%),Abdominal pain (8%),Diarrhea (2%),Nausea (3%),Chromaturia (2%),Vomiting (1%)
<1%
Increased ALT,Anorexia,Appetite increased,Creatinine increased,Diaphoresis,Dizziness,Eye discoloration (pale yellow),Fever,Flatulence,Infection,Malaise,Pruritus,Thinitis,Salivary glands enlarged,Urine discoloration
Interaction
May possibly interact with highly protein-bound drugs e.g. warfarin.
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