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Piramil PLUS 5/25

Tablet-(25mg+5mg)
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Nevian Lifescience PLC

Generic: Hydrochlorothiazide + Ramipril

1 Tablet
৳ 9.39
৳ 10
6% OFF
Alternative Brands For Piramil PLUS 5/25

Medicine Overview of Piramil PLUS 5/25mg+5mg Tablet

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Introduction

Piramil PLUS 5/25 is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce the chances of any future heart attack and stroke. Piramil PLUS 5/25 is taken with or without food, preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine. Nausea, indigestion, taste change, and diarrhea are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or do not go away. Let your doctor know about cough or throat irritation that does not go away. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. Dizziness may occur due to low blood pressure but this gets better with time. Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function and the levels of salts such as potassium checked regularly to make sure that this medicine is working properly.

Uses of Piramil PLUS 5/25

  • Hypertension (high blood pressure)

Side effects of Piramil PLUS 5/25

Common
  • Nausea
  • Indigestion
  • Taste change
  • Diarrhea
  • Stomach pain
  • Headache
  • Dizziness
  • Weakness
  • Glucose intolerance
  • Increased uric acid level in blood
  • Increased blood lipid level
  • Electrolyte imbalance
  • Cough
  • Decreased blood pressure

How to use Piramil PLUS 5/25

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Piramil PLUS 5/25 may be taken with or without food, but it is better to take it at a fixed time.

How Piramil PLUS 5/25 works

Piramil PLUS 5/25 is a combination of two medicines: Ramipril and hydrochlorothiazide which lower blood pressure effectively. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Quick Tips

  • You have been prescribed Piramil PLUS 5/25 for the treatment of high blood pressure.
  • It also lowers your risk of stroke and heart attack.
  • Take it in the morning with breakfast, to avoid getting up at night to urinate.
  • Piramil PLUS 5/25 may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform you doctor about any cough, or throat irritation that doesn't go away.
  • Piramil PLUS 5/25 may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
  • Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.
  • Do not take Piramil PLUS 5/25 if you’re pregnant or planning pregnancy. It can cause birth defects or be fatal to your unborn baby.

Brief Description

Indication

Hypertension, Diabetic nephropathy, Congestive heart failure

Adult Dose

Oral Essential hypertension Adult: Per tablet contains ramipril 2.5 mg and hydrochlorthiazide 12.5 mg: 1 tablet daily up to a max of 4 tablets daily.

Contraindication

Anuria, hypersensitivity, history of angioedema, bilateral renal artery stenosis, unilateral renal artery stenosis

Mode of Action

Ramipril is a long-acting ACE inhibitor which is metabolised into the active metabolite ramiprilat. Supine and standing blood pressures (BP) are reduced witho reflex tachycardia. Ventricular hypertrophy is reversed and renal blood flow increased. In CHF (CHF), pulmonary artery pressure and pulmonary capillary wedge pressure are reduced. Cardiac function is improved. Hydrochlorothiazide is a thiazide diuretic. It increases excretion of Na and chloride in approx equiv amounts. Natriuresis may be accompanied by some loss of K and bicarbonate. The rationale behind this combination is that these have a synergistic effect in lowering BP and offer an advantage of once-daily dosing convenience.

Precaution

Severe renal disease, impaired hepatic, allergy or bronchial asthma, systemic lupus erythematosus, acute gout, diabetes mellitus, elderly, collagen vascular diseases, should be discontinued before carrying out tests for parathyroid function. Pregnancy and lactation.

Side Effect

Pancreatitis, jaundice, diarrhoea, nausea, vomiting, cramps, constipation, gastric irritation, anorexia, aplastic anaemia, agranulocytosis, leukopaenia, haemolytic anaemia, thrombocytopaenia, vasculitis, resp distress, including pneumonitis and pulmonary oedema, photosensitivity, fever, urticaria, rash, hyperglycaemia, glycosuria, hyperuricaemia, muscle spasm, vertigo, paraesthesias, dizziness, headache, restlessness, renal failure, renal dysfunction, interstitial nephritis, erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopoecia, transient blurred vision, xanthopsia, impotence, dizziness, fatigue, headache, abdominal pain, cough, rarely symptomatic hypotension, angioneurotic oedema of face, lips, tongue, glottis and larynx, syncope, renal impairment, hypersensitivity reactions. Potentially Fatal: Anaphylactic reactions, electrolyte imbalance, hypotension.

Interaction

Hydrochlorthiazide in combination with alcohol, barbiturates, or narcotics potentiates orthostatic hypotension. When coadministered with other antihypertensive gives additive effect. Absorption is reduced with cholestyramine and colestipol resins. Hypokalemia is observed with corticosteroids, tubocurarine responsiveness to the muscle relaxant is increased. It decreases the renal clearance of lithium and increases the risk of lithium toxicity. Non-steroidal anti-inflammatory agents can reduce the diuretic and natriuretic effect of hydrochlorthiazide. Ramipril with potassium-sparing diuretics results in severe hyperkaelemia. May increase serum lithium concentration, NSAIDs may reduce the effect of the drug and cause deterioration of renal function.

Buy Piramil PLUS 5/25 from Arogga

In Bangladesh, you can get the original Piramil PLUS 5/25. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Piramil PLUS 5/25 in Bangladesh?

The latest price of Piramil PLUS 5/25 in Bangladesh is 9.39৳. You can buy Piramil PLUS 5/25 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
Piramil PLUS 5/25 may cause excessive drowsiness with alcohol.
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CONSULT YOUR DOCTOR
Piramil PLUS 5/25 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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SAFE IF PRESCRIBED
Piramil PLUS 5/25 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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UNSAFE
Piramil PLUS 5/25 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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CAUTION
Piramil PLUS 5/25 should be used with caution in patients with kidney disease. Dose adjustment of Piramil PLUS 5/25 may be needed. Please consult your doctor. Regular monitoring of blood pressure is recommended for dose adjustment.
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CAUTION
Piramil PLUS 5/25 should be used with caution in patients with liver disease. Dose adjustment of Piramil PLUS 5/25 may be needed. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.