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Revert
Incepta Pharmaceuticals Ltd.
Generic: Cinnarizine + Dimenhydrinate
Safety Advices
বাংলা
English
UNSAFE
Revert may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Revert may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Revert during breastfeeding is not available. Please consult your doctor.
UNSAFE
Revert may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CONSULT YOUR DOCTOR
There is limited information available on the use of Revert in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Revert in patients with liver disease. Please consult your doctor.
Medicine Overview of Revert 20mg+40mg tablet
Introduction
Revert is used to treat vertigo. It is a combination medicine which acts by relaxing vascular smooth muscles of the blood vessels of the ear and improves the blood circulation. It also blocks the action of a chemical messenger that is responsible for lightheadedness in vertigo. Revert should be taken with food to avoid stomach upset. Take this medicine as advised by your doctor and preferably at a fixed time each day. Do not skip any doses, but if you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment and...
... Show moreUses of Revert
- Vertigo
Side effects of Revert
Common
- Drowsiness
- Headache
- Stomach pain
- Dryness in mouth
How to use Revert
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Revert is to be taken with food.
How Revert works
Revert is a combination of two medicines: Cinnarizine and Dimenhydrinate. Cinnarizine is a calcium channel antagonist which works by preventing constriction of the blood vessels of the inner ear. This improves the microcirculation of the ear. Dimenhydrinate is an antiallergic. It blocks the action of a chemical messenger (histamine) that is responsible for light-headedness in vertigo.
Quick Tips
- Revert helps relieve symptoms of vertigo such as nausea, vomiting, dizziness or spinning sensation.
- Take it with food to avoid stomach upset.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Do not drink alcohol while taking this medicine as it may cause increased sleepiness.
- Do not take this medicine if you are pregnant or breastfeeding.
- Do not stop taking Revert without talking to your doctor first.
Brief Description
Indication
Nausea and vomiting, motion sickness, vertigo, meniere's disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders
Administration
Should be taken with food.
Adult Dose
Oral
Peripheral vascular disease
Adult: 75 mg bid or tid.
Motion sickness
Adult: 30 mg 2 hr before travel then 15 mg 8 hrly during the journey if necessary.
Cerebrovascular disorders
Adult: 75 mg once daily.
Vertigo and vestibular disorders
Adult: 30 mg tid or 75 mg 1-2 times daily.
Child Dose
Oral
Motion sickness
Child: 5-12 yr 15 mg 2 hr before travel then 7.5 mg 8 hrly during the journey as necessary.
Vertigo and vestibular disorders
Child: 5-12 yr 15 mg tid.
Contraindication
Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.
Mode of Action
Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity.
Dimenhydrinate is an antihistamine which also has antimuscarinic and central sedative action. It also exerts a depressant action on hyperstimulated labyrinthine function.
Precaution
Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.
Side Effect
Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.
Interaction
Cinnarizine: CNS depressant effect enhanced with alcohol. Action potentiated by domperidone.
Dimenhydrinate: Physically incompatible with aminophylline, hydrocortisone, phenothiazines and some barbiturates in solution.
Potentially Fatal: Potentiates the sedative effects of CNS depressants including alcohol, barbiturates, opioid analgesics, sedatives and neuroleptics. MAOIs, atropine, TCAs enhance antimuscarinic effect. Masks ototoxicity produced by aminoglycoside antibiotics.
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