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Closon
Medicon Pharmaceuticals Ltd.
Generic: Betamethasone 0.05% + Clotrimazole 1% Topical
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Closon may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Closon is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medicine Overview of Closon 0.05%+1% Cream
Introduction
Closon is a combination medicine. It is used to treat various types of skin infections usually the fungal type of skin infections. It minimizes symptoms of inflammation such as redness, swelling, and itching. It also acts against the infection-causing microorganisms. Closon is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your...
... Show moreUses of Closon
- Skin infections
Side effects of Closon
Common
- Application site reactions (burning, irritation, itching and redness)
- Thinning of skin
- Skin peeling
How to use Closon
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Closon works
Closon is a combination of two medicines: Betamethasone and Clotrimazole which treat skin infections. Betamethasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Clotrimazole is an antifungal which stops the growth of fungi on the skin by preventing them from forming their own protective covering.
Quick Tips
- You have been prescribed Closon for the treatment of fungal skin infections.
- It is for use on skin only. Do not use it in your eyes, mouth, or vagina. Rinse with cold water if you accidentally get it in these areas.
- Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
- If you think the area of skin you are treating has become more irritated and infected, you should stop using Closon and consult your doctor.
- Do not use this medicine more often or for longer than advised by your doctor. Inform your doctor if the treated skin area does not improve after 2 weeks of treatment.
Brief Description
Indication
Inflammed tinea pedis, tinea cruris, tinea corporis.
Adult Dose
Adult: Topical: Apply twice daily. Recommended duration: Up to 2 wk (tinea corporis and tinea cruris) and 4 wk (tinea pedis). Max: 45 g/wk.
Child Dose
<17 years: Safety and efficacy not established
Contraindication
Hypersensitivity.
Mode of Action
Betamethasone dipropionate is a corticosteroid that prevents and reduce inflammation by depressing the migration of polymorphonuclear leukocytes and fibroblasts; reversing capillary permeability and lysosomal stabilisation at the cellular level. Clotrimazole is an antifungal agent that binds to phospholipids in the fungal cell membrane. It causes loss of essential intracellular components by altering cell wall permeability.
Precaution
Systemic absorption of betamethasone may result in suppression of the hypothalmic-pituitary-adrenal axis; prolonged or excessive use may increase systemic absorption of the drug. Monitor for signs of infection. Safety and efficacy have not been established in children <17 yr. Elderly. Pregnancy and lactation.
Lactation: Excretion in milk unknown; use with caution
Side Effect
1-10%
Dry skin (2%),Paresthesia (2%),Local burning (2%)
2 wk)
Pregnancy Category Note
Pregnancy There are no available data on topical betamethasone dipropionate or clotrimazole use in pregnant women to identify drug associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes; observational studies suggest an increased risk of low birth weight infants with use of potent or very potent topical corticosteroid during pregnancy Advise pregnant women that therapy may increase risk of having a low birth weight infant and to use drug on the smallest area of skin and for shortest duration possible Animal data In an animal reproduction study, betamethasone dipropionate caused malformations (ie, umbilical hernias, cephalocele, and...
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