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Medicine Overview of Closten 1% Cream
বাংলা
English
Indication
Skin and nail fungal infections, Tinea pedis, Tinea cruris, Tinea corporis, Candidiasis, Pityriasis versicolor
Adult Dose
Topical/Cutaneous Skin and nail fungal infections: Adult: Apply 2 or 3 times daily.
Onychomycosis: for 6 months. Tinea pedis & Dermatomycoses: for 4 weeks.
Child Dose
Tinea Corporis/Tinea Pedis
Apply to affected area q12hr for 4 weeks
Tinea Cruris
>2 years: Apply to affected area q12hr for 2 weeks
Candidiasis
Gently massage sufficient clotrimazole into affected and surrounding area q12hr; reconsider diagnosis if no improvement after 4 weeks
Tinea Versicolor
Gently massage sufficient clotrimazole into affected and surrounding area q12hr; reconsider diagnosis if no improvement after 4 weeks
Contraindication
Hypersensitivity.
Mode of Action
Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.
Precaution
Avoid contact with eyes upon topical application. Childn <3 yrs. Pregnancy, lactation.If local intolerance develops, consider withdrawal of the medicine and institution of appropriate therapy.
Lactation: Excretion in milk unknown; use with caution
Side Effect
Elevated serum AST (SGOT) concentrations (15%)
Topical: Erythema, stinging, irritation; hypersensitivity reactions; contact dermatitis.
Edema, Pruritus, Burning, Stinging, Peeling, Urticaria, Skin fissures
Pregnancy Category Note
Pregnancy
Small amounts of imidazoles may be absorbed systemically following topical and vaginal administration
Lactation
Excretion in milk unknown; use with caution
Interaction
Antagonism with polyene antibiotics.
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