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Cabolac
Incepta Pharmaceuticals Ltd.
Generic: Cabergoline
Safety Advices
বাংলা
English
CAUTION
Caution is advised when consuming alcohol with Cabolac. Please consult your doctor.
SAFE IF PRESCRIBED
Cabolac is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CONSULT YOUR DOCTOR
Cabolac is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Cabolac is usually not used during breastfeeding because it suppresses lactation.
UNSAFE
Cabolac may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Cabolac is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Cabolac may not be needed in these patients. Please consult your doctor.
CAUTION
Cabolac should be used with caution in patients with liver disease. Dose adjustment of Cabolac may be needed. Please consult your doctor.
Medicine Overview of Cabolac 0.5mg Tablet
Introduction
Cabolac is a dopamine agonist. It is used for the treatment of a high level of prolactin. It is also helpful in stopping breast milk production in cases of stillbirth, abortion or miscarriage. Cabolac should be taken with food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this...
... Show moreUses of Cabolac
- High levels of prolactin
Side effects of Cabolac
Common
- Blurred vision
- Drowsiness
- Hot flashes
- Indigestion
- Nausea
- Constipation
- Dizziness
- Fatigue
- Headache
- Vertigo
- Vomiting
How to use Cabolac
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cabolac is to be taken with food.
How Cabolac works
Cabolac works by decreasing the release of prolactin, a hormone that stimulates breast milk production. This stops the production of breast milk in case of stillbirth, abortion or miscarriage.
What if you forget to take Cabolac?
If you miss a dose of Cabolac, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- Cabolac is used to treat conditions such as infertility or abnormal production of breast milk (galactorrhoea) caused due to excess production of a natural hormone called prolactin.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Do not take Cabolac if you are breastfeeding.
- Take it with or after food to avoid side effects such as nausea or indigestion.
- Be cautious while driving or doing anything that requires concentration as Cabolac can cause dizziness and sleepiness.
- Regular monitoring of blood pressure may be advised during treatment with Cabolac.
Brief Description
Indication
Hyperprolactinemia, prolactinomas, parkinson's disease, uterine fibroids, acromegaly, cushing's disease, pituitary adenomas, lactation suppression
Administration
Should be taken with food.
Adult Dose
Oral Inhibition of physiological lactation Adult: 1 mg as a single dose on the 1st day postpartum. Suppression of lactation Adult: 250 mcg every 12 hr for 2 days. Hyperprolactinaemia-associated disorders Adult: Initially, 500 mcg/wk then increased at mthly intervals by 500 mcg/wk according to response. Wkly dose may be admin on a single occasion or in 2 divided doses on separate days; doses >1 mg should be given as divided doses. Usual dose: 1 mg (up to 4.5 mg)/wk. As monotherapy in Parkinson's disease; Adjunct to levodopa treatment in Parkinson's disease Adult: Initially, 0.5 mg daily in monotherapy and...
... Show moreContraindication
Hypersensitivity to ergot derivatives. Uncontrolled hypertension.
Mode of Action
Cabergoline is a long-acting dopamine D2-agonist. It inhibits prolactin secretion through hypothalamic inhibitory control exerted through the release of dopamine.
Precaution
CV disease, Raynaud's syndrome, renal or hepatic impairment, peptic ulcer, GI bleeding, history of psychosis, hypertension. May affect ability to drive or operate machinery. Pregnancy, lactation. Prolonged use and/or usage of high doses may lead to psychiatric disorders, pleural/retroperitoneal fibrosis or cardiac valvular fibrosis. Monitor serum prolactin level mthly until normalisation. Monitor hepatic function regularly in patients with hepatic impairment.
Lactation: excretion in milk unknown; use with caution
Side Effect
>10%
Nausea (27%),Headache (26%),Dizziness (15%),Constipation (10%)
1-10%
Asthenia (9%),Fatigue (7%),Abdominal pain (5%),Somnolence (5%),Postural hypotension (4%),Depression (3%),Dyspepsia (2%),Nervousness (2%),Abnormal vision (1%),Breast pain (1%),Dysmenorrhea (1%),Hot flashes (1%),Paresthesia (1%)
Potentially Fatal: Risk of serotinin syndrome with sibutramine; avoid combination.
Pregnancy Category Note
Pregnancy Category: B
Lactation: excretion in milk unknown; not recommended
Interaction
Increased risk of orthostatic hypotension when used with antihypertensives. May increase vasoconstriction effect of dopamine. May reduce vasodilation effect of nitroglycerin. Concurrent use with SSRIs or TCAs may increase the risk of serotonin syndrome.
Potentially Fatal: Risk of serotonin syndrome with sibutramine.
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