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Arexel
Jayson Pharmaceuticals Ltd.
Generic: Artemether + Lumefantrine
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Arexel. Please consult your doctor.
CONSULT YOUR DOCTOR
Arexel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Arexel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Arexel may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Arexel should be used with caution in patients with severe kidney disease. Dose adjustment of Arexel may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with severe kidney disease.
CAUTION
Arexel should be used with caution in patients with severe liver disease. Dose adjustment of Arexel may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with severe liver disease.
Medicine Overview of Arexel 20mg+120mg Tablet
Introduction
Arexel is a combination medicine that is prescribed to treat malaria. It fights against the infection by preventing the growth of the parasites inside the body. Arexel is a prescription medicine. It is to be taken with food and take it at a fixed time regularly. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. A missed dose should be taken as soon as you remember. The course of the treatment should be completed for better efficacy. Some common side...
... Show moreUses of Arexel
- Malaria
Side effects of Arexel
Common
- Headache
- Loss of appetite
- Dizziness
- Weakness
- Joint pain
- Muscle pain
How to use Arexel
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arexel is to be taken with food.
How Arexel works
Arexel is a combination of two antiparasitic medicines: Artemether and Lumefantrine, which treats malaria. These medicines work by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.
Quick Tips
- You have been prescribed Arexel for the treatment of acute uncomplicated malaria that is resistant to other antimalarial medications such as chloroquine.
- Tips to reduce the chance of being bitten by mosquitoes:
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- It should be taken with food or drinks rich in fat such as milk.
- It may cause fatigue and dizziness. Use caution while driving or doing anything that requires concentration.
- If you vomit within 1 hour of taking the tablets, take another dose.
- Inform your doctor if you have kidney, liver or heart disease.
Brief Description
Indication
Oral
Adults (weighing 35 kg and above): Administer 24 tablets over 3 days; use a 3-day treatment schedule with total of 6 doses.
Day 1: 4 tablets initially and 4 tablets again after 8 hours.
Days 2 & 3: 4 tablets BID (morning & evening).
Administration
Artemether causes QT prolongation in some patients. Thus concomitant use of erythromycin, terfenadine, procainamide, quinidine, disopyramide, amiodarone, bretylium, bepridil, sotalol, astemizole, probucol, tricyclic antidepressants, phenothiazines may be avoided.
Adult Dose
Pregnancy and lactation. Avoid concomitant use of drugs known to prolong QT interval or monitor such patients.
Lactation: not known if either component enters breast milk, use caution
Renal Dose
Artemether is a potent and rapidly acting blood schizontocide. Artemether and active metabolite (DHA): via endoperoxide.
Lumefantrine: unknown; possibly inhibits beta-hematin formation
Both artemether and lumentantrine inhibit nucleic acid and protein synthesis
Contraindication
Oral Children (weighing 35 kg and above or more than 12 years of age): Administer 24 tablets over 3 days; use a 3-day treatment schedule with total of 6 doses. Day 1: 4 tablets initially and 4 tablets again after 8 hours. Days 2 & 3: 4 tablets BID (morning & evening). Children: < 12 years 5 to <15 kg: Administer 6 tablets over 3 days; 1 tablet initially and again after 8 hours on first day; follow by 1 tablet BID (morning & evening) for the next 2 days. 15 to <25 kg: Administer 12 tablets over 3 days;...
... Show moreMode of Action
Should be taken with food.
Precaution
Acute uncomplicated malaria, Falciparum malaria
Pregnancy Category Note
>10%
Abdominal pain (17%),Anorexia (40%),Arthralgia (34%),Asthenia (38%),Chills (23%),Dizziness (39%),Fatigue (17%),Headache (56%),Myalgia (32%),Nausea (26%),Palpitations (18%),Pyrexia (25%),Sleep disorder (22%),Vomiting(17%)
1-10%
Anemia (4%),Cough (6%),Diarrhea (7%),Hepatomegaly (9%),Malaise (3%),Nasopharyngitis (3%),Pruritus (4%),Rash (3%),Splenomegaly (9%),Vertigo (3%)
Interaction
Hypersensitivity.
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