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Methyphen 10
General Pharmaceuticals Ltd.
Generic: Methylphenidate Hydrochloride
Safety Advices
বাংলা
English
UNSAFE
Methyphen 10 may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Methyphen 10 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Methyphen 10 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Methyphen 10 may cause side effects which could affect your ability to drive.
You may feel dizzy, have problems focussing or have blurred vision when taking Methyphen 10. This may affect your driving ability.
CONSULT YOUR DOCTOR
There is limited information available on the use of Methyphen 10 in patients with kidney disease. Please consult your doctor.
Caution should be exercised in patients with underlying kidney disease.
CONSULT YOUR DOCTOR
There is limited information available on the use of Methyphen 10 in patients with liver disease. Please consult your doctor.
Medicine Overview of Methyphen 10mg Tablet
Introduction
Methyphen 10 is a medicine used in the treatment of attention deficit hyperactivity disorder (a behavioral disorder in children marked by poor concentration, hyperactivity, and learning difficulties). It helps to improve attention span, concentration and reduces impulsive behavior. Methyphen 10 may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important...
... Show moreUses of Methyphen 10
- Attention deficit hyperactivity disorder (ADHD)
Side effects of Methyphen 10
Common
- Headache
- Insomnia (difficulty in sleeping)
- Abdominal pain
- Nervousness
How to use Methyphen 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Methyphen 10 may be taken with or without food, but it is better to take it at a fixed time.
How Methyphen 10 works
Methyphen 10 is a CNS stimulant. It works by improving the activity of certain parts of the brain by increasing the levels of certain chemicals (norepinephrine and dopamine). Methyphen 10 is a CNS stimulant. It works by improving the activity of certain parts of the brain by increasing the levels of certain chemicals (norepinephrine and dopamine).
What if you forget to take Methyphen 10?
If you miss a dose of Methyphen 10, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- It has high habit-forming potential. Do not take more than prescribed.
- Take it early in the morning to prevent insomnia later that night.
- Methyphen 10 may raise your blood pressure and pulse. Monitor your blood pressure regularly.
- Use caution while driving or doing anything that requires concentration as Methyphen 10 can cause dizziness and sleepiness.
- It can cause a loss of appetite, which can slow growth rate, especially in children. Monitor your child’s height and weight regularly while taking this medicine.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking medicine without talking to your doctor first.
Brief Description
Indication
Narcolepsy, Attention Deficit Hyperactivity Disorder
Administration
Should be taken on an empty stomach. Take 30-45 min before meals.
Adult Dose
Oral
Narcolepsy
Adult: 20-30 mg/day PO divided q8-12hr, 30-45 minutes before meals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate
Attention Deficit Hyperactivity Disorder
20-30 mg/day PO divided q8-12hr, 30-45 minutes before meals; may gradually increase dose at weekly intervals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate
Child Dose
Oral
Narcolepsy
Child >6 years: 5 mg PO BID 30-45 minutes before breakfast and lunch initially; may increase by 5-10 mg/day at weekly intervals; not to exceed 60 mg/day divided BID/TID
Narcolepsy
5 mg PO q12hr; may increase by 5-10 mg/day weekly; not to exceed 60 mg/day
<6 years: Safety and efficacy not established
Contraindication
Marked anxiety, tension, agitation; glaucoma; Tourette's syndrome or tics. Known severe structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, or other serious cardiac disorders that could increase the risk of sudden death. Extended-release form: Severe hypertension, heart failure, arrhythmia, hyperthyroidism, recent MI or angina.
Mode of Action
Methylphenidate is a central stimulant and indirect-acting sympathomimetic.
Precaution
Pregnancy and lactation. History of alcohol or drug abuse. Hypertension and other CV disorders that might be exacerbated by increases in BP or heart rate. Pre-existing psychosis or bipolar disorder; monitor for symptoms of aggression or hostility. History of seizure disorder. Children <6 yr (growth suppression); monitor growth during therapy. May impair ability to drive or operate machinery. Transdermal: Avoid exposure of application site to any direct external heat source.
Lactation: Unknown; avoid during breastfeeding; use caution
Side Effect
Angina, arrhythmia, cerebral arteritis, cerebral occlusion, changes in BP, MI, necrotising vasculitis, palpitation, pulse changes, tachycardia; depression, dizziness, drowsiness, fever, headache, insomnia, nervousness, neuroleptic malignant syndrome (NMS), Tourette's syndrome, toxic psychosis; erythema multiforme, exfoliative dermatitis, hair loss, rash, urticaria; growth retardation; abdominal pain, anorexia, diarrhoea, nausea, vomiting, weight loss; anaemia, leukopenia, thrombocytopenic purpura, thrombocytopenia; abnormal LFTs, hepatic coma, increased transaminases; arthralgia, dyskinesia; blurred vision, visual accommodation disturbance; cough, pharyngitis, sinusitis, upper respiratory tract infection; accidental injury, hypersensitivity. Transdermal: Insomnia, decreased appetite; nausea; tic, emotional instability; vomiting, anorexia; nasal congestion, nasopharyngitis; weight loss.
Interaction
May reduce effects of antihypertensive agents. Reduced serum level with carbamazepine. Increased serum levels or effects with CYP2D6 inhibitors e.g. chlorpromazine, delavirdine, fluoxetine, miconazole, paroxetine, pergolide, quinidine, quinine, ritonavir, ropinirole. May increase serum levels of phenytoin, TCAs. Possible severe hypertension and tachycardia with sibutramine. CNS depression with alcohol.
Potentially Fatal: Severe toxic reactions with clonidine. Increased risk of hypertensive crisis with MAOIs.
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