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Locin
Globe Pharmaceuticals Ltd.
Generic: Levofloxacin 0.5% Eye prep
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Locin is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Locin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Locin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Medicine Overview of Locin 0.50% Eye Drop
Introduction
Locin is an antibiotic, used in the treatment of bacterial infections of the eye. It relieves the symptoms of the infection by stopping the further growth of the causative microorganisms. Locin is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. Avoid skipping any doses and finish the full course of treatment even if you feel better. It may cause eye irritation and burning sensation in the...
... Show moreUses of Locin
- Bacterial eye infections
Side effects of Locin
Common
- Eye irritation
- Burning sensation
How to use Locin
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Locin works
Locin is an antibiotic. It treats bacterial eye infections by preventing the bacteria from dividing and repairing. It does so stopping the action of a bacterial enzyme called DNA-gyrase.
What if you forget to take Locin?
If you miss a dose of Locin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- You have been prescribed Locin for the treatment of bacterial infections of the eye.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the medication.
- Do not touch the tip to any surface, or to your eye, to avoid contamination.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- It may cause short term blurring of vision when first used. Use caution before driving or using machines.
- Do not wear contact lenses until your infection clears up.
- Make sure to use within 4 weeks of opening the medication.
Brief Description
Indication
Bacterial conjunctivitis, Ocular infections
Adult Dose
Ophthalmic
Bacterial conjunctivitis
Adults:
Days 1 and 2: Instill 1-2 drops in the affected eye(s) every 2 hours while awake, up to 8 times per day.
Days 3 through 7: Instill 1-2 drops in the affected eye(s) every 4 hours while awake, up to 4 times per day.
Child Dose
Ophthalmic
Bacterial conjunctivitis
Children 1 year of age and older:
Days 1 and 2: Instill 1-2 drops in the affected eye(s) every 2 hours while awake, up to 8 times per day.
Days 3 through 7: Instill 1-2 drops in the affected eye(s) every 4 hours while awake, up to 4 times per day.
Children up to 1 year of age:
Use and dose must be determined by the physician.
Contraindication
Levofloxacin is contraindicated in patients with a history of hypersensitivity to levofloxacin, quinolone antimicrobial agents, or any other components of this product.
Mode of Action
Levofloxacin exerts antibacterial action by inhibiting bacterial topoisomerase IV and DNA gyrase, the enzymes required for DNA replication, transcription repair and recombination. It has in vitro activity against a wide range of gram-negative and gram-positive microorganisms.
Precaution
Hypersensitivity to levofloxacin or other quinolones. Contaminating the applicator tip with material from the eye, fingers or other source.
Lactation: May be distributed into milk; use caution
Side Effect
Transient decrease in vision,Transient ocular burning,Ocular pain or discomfort,Foreign body sensation,Headache,Fever,Pharyngitis,Photophobia,Allergic reactions,Lid edema,Ocular dryness,Ocular itching
Interaction
Additive effects on QT interval prolongation w/ class IA (e.g. quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmics, fluoxetine or imipramine. Reduced absorption w/ sucralfate, didanosine, antacids containing Mg or Al, dietary supplements containing Zn, Ca, Mg or Fe. Altered glucose levels w/ antidiabetic agents (e.g. insulin, glibenclamide). Increased risk of severe tendon disorders w/ corticosteroids. Increased risk of CNS stimulation and seizures w/ NSAIDs. Increased prothrombin time w/ warfarin.
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