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Nispore
Incepta Pharmaceuticals Ltd.
Generic: Fluconazole 0.3% Eye prep
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Nispore is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Nispore is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Nispore may cause side effects which could affect your ability to drive.
Nispore may cause dizziness or seizures. This may affect your ability to drive.
Medicine Overview of Nispore 0.30% Eye Drop
Introduction
Nispore is an antifungal medication which treats eye infections. It works by killing the fungi in the eye by destroying their cell membrane. This relieves discomfort, itching and irritation in the eye. Nispore is for external use only. Take it in the dose and duration as advised by your doctor. Wash your hands before and after applying the medicine. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. This medicine should be used regularly to get the most benefit from it. If you...
... Show moreUses of Nispore
- Fungal infections of eye
Side effects of Nispore
Common
- Eye irritation
- Stinging in the eyes
How to use Nispore
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Nispore works
Nispore is an antifungal medication which treats eye infections. It works by killing the fungi in the eye by destroying their cell membrane. This relieves discomfort, itching and irritation in the eye.
What if you forget to take Nispore?
If you miss a dose of Nispore, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Your doctor has prescribed Nispore to treat fungal infections of the eye.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Apply pressure on the corner of the eye (close to the nose) for about 1 minute immediately after instilling the drop.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- Stinging sensation may occur for 1-2 mins. Notify your doctor if it persists for longer.
- If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.
- Make sure to use within 4 weeks of opening the bottle.
Brief Description
Indication
Fungal corneal ulcers, Fungal keratitis, Fungal eye infections
Adult Dose
Adult: 1 - 2 drops to be instilled into the affected eye 5 times daily.
Contraindication
The drug is contraindicated in patients with hypersensitivity to azoles.
Mode of Action
Fluconazole decreases ergosterol synthesis by interfering w/ cytochrome P450 activity, thus inhibiting cell membrane formation of susceptible fungi including B. dermatitidis, Candida spp., C. immitis, C. neoformans, Epidermophyton spp., H. capsulatum, Micosporum spp., Trichophyton spp.
Precaution
Use of fluconazole may result in overgrowth of non-susceptible strains of candida other than C. albicans.
Side Effect
This drug is generally well tolerated. Eosinophillia has been reported in some patients.
Interaction
May increase plasma concentrations of oral hypoglycaemics (e.g. tolbutamide, glyburide, glipizide), phenytoin, theophylline, tofacitinib, rifabutin. May increase prothrombin time w/ anticoagulants. May cause significant increase in ciclosporin levels in renal transplant patients w/ or w/o renal impairment. Rifampicin reduces fluconazole levels. May increase risk of nephrotoxicity w/ tacrolimus. May increase the effect of short-acting benzodiazepines (e.g. midazolam).
Potentially Fatal: Increased risk of cardiac arrhythmias or QT prolongation w/ terfenadine, cisapride, astemizole, pimozide, quinidine, halofantrine and erythromycin.
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