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Misoclo 50/200

Name: Misoclo 50/200 50mg+200mcg Tablet
Brand: General Pharmaceuticals Ltd.
SKU: 23268
Price: 9.15 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Tablet - (50mg+200mcg)

General Pharmaceuticals Ltd.

Generic: Diclofenac Sodium + Misoprostol

Medicine Overview of Misoclo 50/200 50mg+200mcg Tablet

বাংলা

English

Indication

Rheumatoid arthritis, Osteoarthritis, Joint and muscular pains

Administration

Swallow tablet whole, do not chew or crush Do not take with antacids

Adult Dose

Osteoarthritis 50 mg/200 mcg, 75mg/200mcg: 1 tab PO three times daily; not to exceed 200 mcg misoprostol/dose or 800 mcg/day Rheumatoid Arthritis 50 mg/200 mcg, 75mg/200mcg: 1 tab PO three or four times daily; not to exceed 200 mcg misoprostol/dose or 800 mcg/day If not tolerated may reduce frequency to twice daily Three times daily dose of misoprostol is more protective than when given twice daily

Child Dose

Safety & efficacy not established

Contraindication

Diclofenac Sodium and Misoprostol combination is contraindicated in women who are pregnant because of the abortive property of the Misoprostol component.

Mode of Action

Diclofenac: Inhibits cyclooxygenase-1 (COX-1) & -2 (COX-2), thereby inhibiting prostaglandin synthesis; has anti-inflammatory, antipyresis, and analgesic properties. Misoprostol: Replaces protective prostaglandins consumed by prostaglandin-inhibiting therapies (NSAID-induced ulcers).

Precaution

Patients with an underlying condition such as inflammatory bowel disease or those in whom dehydration should be monitored carefully if Diclofenac Sodium 50 mg plus Misoprostol 200 mcg is prescribed. The pharmacological activity in reducing fever and inflammation may diminish the utility of these diagnostic signs in detecting complications of presumed noninfectious, painful conditions. Lactation: Enters breast milk; use with caution

Side Effect

>10% Rash including erythematous, rash macular and maculo-papular (18%),Pyrexia (15%),Urticaria (13%),Flushing (13%) 1-10% Hypertension (10%),Hyperhydrosis (8%),Decreased oxygen saturation (8%),Cough (8%),Tachypnea (8%),Tachycardia (8%),Urticaria (8%),Anaphylaxis (7%),Chest discomfort (7%),Muscle twitching (7%),Erythema (5%),Vomiting (5%),Rigors (5%),Pallor (5%),Cyanosis (5%),Agitation (5%),Tremor (5%),Myalgia (5%),Flushing (5%),Peripheral edema (3%),Pruritus (3%),Rash, papular (3%),Throat tightness (3%) <1% Fatigue,Malaise,Chills,Edema,Atrial fibrillation,Congestive heart failure,Myocardial infarction,Phlebitis,Vasculitis,Syncope,Dysphagia,Enteritis,Peptic ulcer,Vaginitis,Breast pain,Dysmenorrhea,Uterine cramping,Ulcerative stomatitis,Impotence,Perineal pain,Glycosuria,Alopecia

Pregnancy Category Note

Pregnancy Category: X Lactation: Enters breast milk; use with caution

Interaction

May increase serum levels of methotrexate. Concomitant use w/ other NSAIDs or anticoagulants (e.g. warfarin) is associated w/ higher risk of GI bleeding. Increased risk of nephrotoxicity w/ ciclosporin or triamterene. May increase the risk of developing corneal complications in patients w/ significant pre-existing corneal inflammation when use concomitantly w/ ophth preparation containing corticosteroids. Colestyramine and colestipol reduce the bioavailability of diclofenac. Decreased plasma concentration when administered after sucralfate. Ophth application of diclofenac may reduce the efficacy of ophth acetylcholine and carbachol. May increase serum levels of lithium and digoxin. May increase effects of oxytocin. Increased risk of misoprostol-induced...

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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Misoclo 50/200

Tablet - (50mg+200mcg)

General Pharmaceuticals Ltd.

Generic: Diclofenac Sodium + Misoprostol

Additional Offers

Cashback

৳50

For purchasing above ৳5000+

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৳40

For purchasing above ৳4000+

Cashback

৳30

For purchasing above ৳3000+

Cashback

৳20

For purchasing above ৳2000+

Cashback

৳10

For purchasing above ৳1000+

Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

Misoclo 50/200

Medicine Overview of Misoclo 50/200 50mg+200mcg Tablet

Misoclo 50/200

Alternative Brands For Misoclo 50/200