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Pza Ciba

Tablet-(500mg)
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Nevian Lifescience PLC

Generic: Pyrazinamide

1 Tablet
৳ 2.21
৳ 2.35
6% OFF

Medicine Overview of Pza Ciba 500mg Tablet

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Introduction

Pza Ciba is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. Pza Ciba is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects. Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver), increased liver enzymes and joint pain as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and might need dose modification. Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Pza Ciba

  • Tuberculosis (TB)

Side effects of Pza Ciba

Common
  • Jaundice
  • Hepatitis (viral infection of liver)
  • Increased liver enzymes
  • Joint pain

How to use Pza Ciba

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pza Ciba may be taken with or without food, but it is better to take it at a fixed time.

How Pza Ciba works

Pza Ciba is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme), which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.

What if you forget to take Pza Ciba?

If you miss a dose of Pza Ciba, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • Pza Ciba along with other medications effectively treats tuberculosis.
  • Do not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Avoid drinking alcohol while taking Pza Ciba as this may increase the risk of side effects on the liver.
  • Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Pza Ciba as it may make hormonal contraceptives such as the pill less effective.

Brief Description

Indication

Tuberculosis

Administration

Should be taken with food.

Adult Dose

Oral Tuberculosis Adult: As part of a multidrug regimen: For standard unsupervised 2-mth treatment: <50 kg: 1.5 g daily; >50 kg: 2 g daily. For intermittent supervised 2-mth treatment: <50 kg: 2 g 3 times wkly; >50 kg: 2.5 g 3 times wkly. Hepatic impairment: Severe: Contraindicated.

Child Dose

Oral Tuberculosis Child: As part of a multidrug regimen: For standard unsupervised 2-mth treatment: 35 mg/kg daily. For intermittent supervised 2-mth treatment: 50 mg/kg 3 times wkly.

Renal Dose

Renal impairment: May need dose reduction.

Contraindication

Hypersensitivity; existing liver disease; acute gout or hyperuricaemia. Porphyria. Pregnancy and lactation.

Mode of Action

Pyrazinamide may be bacteriostatic or bactericidal in action, depending on the concentration of the drug attained at the site of the infection and the susceptibility of the infecting organism. Its activity appears to partly depend on conversion of the drug to pyrazinoic acid (POA), which lowers the pH of the environment below that which is necessary for growth of Mycobacterium tuberculosis. Susceptible strains of M. tuberculosis produce pyrazinamidase, an enzyme that deaminates pyrazinamide to POA, and the in vitro susceptibility of a given strain of the organism appears to correspond to its pyrazinamidase activity.

Precaution

Patient w/ DM, history of gout. Mild to moderate hepatic and renal impairment. Pregnancy and lactation. Monitoring Parameters Monitor liver function, serum uric acid, sputum culture; chest x-ray 2-3 mth into treatment and at completion.

Side Effect

1-10% Malaise,Nausea,Vomiting,Anorexia,Arthralgia,Myalgia <1% Fever,Rash,Itching,Acne,Photosensitivity,Gout,Dysuria,Porphyria,Thrombocytopenia,Hepatotoxicity,Interstitial nephritis Potentially Fatal: Severe liver damage, fulminant hepatitis.

Interaction

Antagonises the effect of uricosuric agents (e.g. probenecid, sulfinpyrazone). May reduce the contraceptive effect of oestrogens. May inactivate oral typhoid vaccine. May increase the serum concentration of ciclosporin. May enhance the hepatotoxic effect of rifampicin.

Buy Pza Ciba from Arogga

In Bangladesh, you can get the original Pza Ciba. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Pza Ciba in Bangladesh?

The latest price of Pza Ciba in Bangladesh is 2.21৳. You can buy Pza Ciba at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CAUTION
Caution is advised when consuming alcohol with Pza Ciba. Please consult your doctor.
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CONSULT YOUR DOCTOR
Pza Ciba may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Pza Ciba is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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CONSULT YOUR DOCTOR
It is not known whether Pza Ciba alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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CAUTION
Pza Ciba should be used with caution in patients with severe kidney disease. Dose adjustment of Pza Ciba may be needed. Please consult your doctor. Kidney function tests are advised before you start taking this medicine.
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CAUTION
Pza Ciba should be used with caution in patients with liver disease. Dose adjustment of Pza Ciba may be needed. Please consult your doctor. Regular monitoring of liver function tests is advised before and after the start of the treatment.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.