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Daclacee

Tablet-(60mg)
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Jenphar Bangladesh Ltd.

Generic: Daclatasvir

1 Tablet
৳ 371.68
৳ 400
7% OFF

Medicine Overview of Daclacee 60mg Tablet

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Introduction

Daclacee is an antiviral medication. It is used along with other medications for the treatment of chronic hepatitis C virus (HCV) infection. It works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of time. Daclacee should be taken in the dose and duration as advised by your doctor. It should be taken with or without food, preferably at a fixed time. Do not skip any doses and finish the full course of treatment even if you feel better If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. It has fewer side effects as compared to other similar medicines, like fatigue, headache, nausea, insomnia (difficulty sleeping) and anemia (low red blood cell count). Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Daclacee

  • Chronic hepatitis C virus (HCV) infection

Side effects of Daclacee

Common
  • Fatigue
  • Headache
  • Nausea
  • Insomnia (difficulty in sleeping)
  • Anemia (low number of red blood cells)

How to use Daclacee

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Daclacee may be taken with or without food, but it is better to take it at a fixed time.

How Daclacee works

Daclacee is an antiviral medication. It works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of time.

Quick Tips

  • Daclacee is used along with other medications for the treatment of chronic hepatitis C virus (HCV) infection.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It has fewer side effects compared to other similar medications.
  • Take it with food, preferably at the same time everyday.
  • You will usually need to take this medicine every day for either 12 or 24 weeks.
  • It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you.
  • Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly.
  • Do not stop taking Daclacee without your doctor’s advice.

Brief Description

Indication

Chronic hepatitis C virus infection in adults.

Administration

May be taken with or without food.

Adult Dose

Hepatitis C Indicated for use with sofosbuvir for chronic hepatitis C virus (HCV) genotypes 1 and 3 infection Genotype 1 Without cirrhosis or with compensated (Child-Pugh A) cirrhosis: 60 mg (plus sofosbuvir 400 mg) PO qDay for 12 weeks Decompensated (Child-Pugh B or C) cirrhosis or posttransplant: 60 mg (plus sofosbuvir 400 mg) PO qDay plus ribavirin for 12 weeks Genotype 3 Without cirrhosis: 60 mg (plus sofosbuvir 400 mg) PO qDay for 12 weeks Compensated (Child-Pugh A) or decompensated (Child-Pugh B or C) cirrhosis, or posttransplant: 60 mg (plus sofosbuvir 400 mg) PO qDay plus ribavirin for 12 weeks Hepatic impairment (any degree): No dose adjustment required

Renal Dose

Renal impairment (any degree): No dose adjustment required

Contraindication

Hypersensitivity. Co-administration w/ strong CYP3A4 inducers & P-gp eg phenytoin, carbamazepine, oxcarbazepine, phenobarb, rifampicin, rifabutin, rifapentine, systemic dexamethasone, St. John's wort.

Mode of Action

Inhibits NS5A, a nonstructural protein encoded by HCV. Binds to the N-terminus within domain 1 of NS5A, which may cause structural distortions that interfere with NS5A functions, and thereby inhibits both viral RNA replication and virion assembly.

Precaution

Patients w/ genotype 1 infection & compensated cirrhosis; receiving amiodarone; decompensated liver disease; prior exposure to a NS5A inhibitor; pre-, peri- or post-liver transplant or other organ transplant; HIV/HCV, HBV co-infected patients. Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May impair ability to drive or operate machinery. Women of childbearing potential. Pregnancy & lactation. Childn & adolescents <18 yr. Lactation Unknown if distributed in human breast milk

Side Effect

>10% Headache (14%),Fatigue (14%) 1-10% Nausea (8%),Diarrhea (5%),Elevated lipase, >3 x ULN (2%)

Pregnancy Category Note

Pregnancy No data in pregnant women are available If daclatasvir and sofosbuvir are administered with ribavirin, the warnings and precautions for ribavirin, in particular the pregnancy avoidance warning, apply to this combination regimen (see ribavirin prescribing information) Lactation Unknown if distributed in human breast milk The development and health benefits of breastfeeding should be considered along with the mother’s clinical need for the drug and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition

Interaction

May lead to lower exposure & loss of efficacy w/ phenytoin, carbamazepine, oxcarbazepine, phenobarb, rifampicin, rifabutin, rifapentine, systemic dexamethasone & St. John's wort. Decreased plasma levels & therapeutic effect w/ strong or moderate CYP3A4 & P-gp inducers. Increased plasma levels w/ strong CYP3A4 inhibitors. May increase systemic exposure of P-gp, OATP, 1B1, OCT1 or BCRP substrates. Boceprevir, telaprevir, atazanavir/ritonavir, efavirenz, cobicistat-containing, clarithromycin, telithromycin, erythromycin, dabigatran, etexilate, posaconazole, voriconazole, amiodarone, digoxin, Ca channel blockers, HMG-CoA reductase inhibitors.

Buy Daclacee from Arogga

In Bangladesh, you can get the original Daclacee. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Daclacee in Bangladesh?

The latest price of Daclacee in Bangladesh is 371.68. You can buy Daclacee at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Daclacee. Please consult your doctor.
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CONSULT YOUR DOCTOR
Daclacee may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Daclacee is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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CONSULT YOUR DOCTOR
It is not known whether Daclacee alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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SAFE IF PRESCRIBED
Daclacee is safe to use in patients with kidney disease. No dose adjustment of Daclacee is recommended.
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SAFE IF PRESCRIBED
Daclacee is safe to use in patients with liver disease. No dose adjustment of Daclacee is recommended.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.