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Cosmotrin
Beximco Pharmaceuticals Ltd.
Generic: Tretinoin Topical
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Cosmotrin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Cosmotrin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medicine Overview of Cosmotrin 0.25% Cream
Introduction
Cosmotrin is a form of vitamin A that is used to treat acne which appears as spots or pimples on your face, chest or back. It also helps to smooth rough facial skin and to reduce fine wrinkles on the skin. Cosmotrin reduces excessive oil production of the skin. Ideally, a pinpoint application at nighttime is recommended for the duration prescribed by your doctor. The amount you need and for how long you need to take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer...
... Show moreUses of Cosmotrin
- Acne
Side effects of Cosmotrin
Common
- Erythema (skin redness)
- Skin irritation
- Dry skin
- Dry lips
- Pale red skin
- Increased sensitivity to light
How to use Cosmotrin
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
How Cosmotrin works
Cosmotrin is a form of vitamin A. When applied on skin, it reduces oil production in the skin, replenishes acne-prone skin and helps keep your pores open.
What if you forget to take Cosmotrin?
If you miss a dose of Cosmotrin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- You have been prescribed Cosmotrin for the treatment of acne.
- Clean the affected area with water and a non-medicated soap. Let it dry for 20-30 minutes before applying Cosmotrin.
- It may increase the severity of the spots or pimples in the first few weeks of use. Continue using it as prescribed by your doctor.
- It may cause a stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists.
- Avoid exposure to sunlight while using Cosmotrin as it increases the sensitivity of your skin. Use protective measures such as sunscreen or protective clothing.
- Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
- Avoid taking tetracycline (e.g. doxycycline) as it may reduce the Cosmotrin activity.
- Do not use Cosmotrin if you are pregnant.
- Inform your doctor if excessive skin dryness or skin sensitivity take place.
Brief Description
Indication
Acne, Mottled hyperpigmentation, Roughness and fine wrinkling of photodamaged skin
Adult Dose
Topical/Cutaneous
Acne vulgaris
Adult: Apply once, usually at bedtime, onto affected area which has been previously cleansed to remove excessive oiliness and dried.
Therapeutic response may be seen after 6-8 wk.
Mottled hyperpigmentation, roughness and fine wrinkling of photodamaged skin
Adult: Apply a pea-sized amount onto entire face once daily at night.
Therapeutic response may be seen after 6 mth.
Child Dose
Topical/Cutaneous
Acne Vulgaris
12 years: Apply once, usually at bedtime, onto affected area
Contraindication
Hypersensitivity to retinoids. Application to eczematous, sunburnt or abraded skin. Pregnancy, lactation.
Mode of Action
Tretinoin is a trans-retinoic acid form of vitimin A. It stimulates mitosis and turnover of follicular epithelial cells and reduce their cohesiveness. This facilitates extrusion of existing comedones and prevents formation of new comedone. It also exhibits thinning effect on the stratum corneum. In acute promyelocytic leukaemia, it induces cellular differentiation and decreases proliferations.
Precaution
Avoid concomitant topical applications, esp keratolytic agents. Avoid exposure to sunlight, UV light and weather extremes (e.g. cold). Keep away from eyes, mouth, angles of nose, mucous membranes or open wounds. In case of severe local erythema, oedema, blistering or crusting, use less frequently or discontinue. Avoid medicated or drying soaps, abrasive soaps and cleansers, frequent washing and harsh scrubbing. Avoid use of topical preparations with high concentrations of alcohol, menthol, spices or lime.
Side Effect
Initial exacerbation of symptoms, skin irritation, stinging on application, oedema, blistering, crusting of the skin, erythema, scaling, photosensitivity, temporary hypo/hyperpigmentation.
Interaction
Enhances percutaneous absorption of minoxidil. Increased risk of fatal thrombotic complications with antifibrinolytic. Increased tretinoin concentrations with azole antifungals. Enhances peeling action of sulphur, resorcinol, benzoyl peroxide, salicylic acid. Increased photosensitivity with photosensitising medications eg, thiazides, tetracyclines, fluoroquinolones, phenothiazines and sulfonamides.
Potentially Fatal: Increased risk of intracranial pressure with tetracyclines.
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