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Dieta Plus 2

Tablet-(30mg+2mg)
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Pacific Pharmaceuticals Ltd.

Generic: Glimepiride + Pioglitazone

1 Tablet
৳ 11.62
৳ 12.50
7% OFF

Medicine Overview of Dieta Plus 2 30mg+2mg Tablet

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Introduction

Dieta Plus 2 is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilisation of insulin, thereby lowering the blood sugar levels. Dieta Plus 2 should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia). Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and respiratory tract infection. Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Dieta Plus 2

  • Type 2 diabetes mellitus

Side effects of Dieta Plus 2

Common
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Taste change
  • Diarrhea
  • Stomach pain
  • Headache
  • Edema (swelling)
  • Weight gain
  • Blurred vision
  • Bone fracture
  • Respiratory tract infection

How to use Dieta Plus 2

Use it as advised by your doctor or check the label for directions before use. Dieta Plus 2 is to be taken with food.

How Dieta Plus 2 works

Dieta Plus 2 is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

Quick Tips

  • Take it with food to lower your chance of having an upset stomach.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Brief Description

Indication

Type 2 DM

Adult Dose

Oral Type 2 diabetes mellitus Adult: 30 mg/2 mg, OR 30 mg/4 mg: Initially, 1 tab once daily then titrate gradually as needed. Elderly: Should start w/ glimepiride 1 mg/day prior to initiating pioglitazone + glimepiride combination. Hepatic Impairment 1 mg/day glimpiride PO prior to initiating glimepiride/pioglitazone; titrate conservatively to avoid hypoglycemia Baseline ALT <2.5 xULN: Use caution Baseline ALT >2.5 xULN: Do not initiate ALT >3 xULN or jaundice after initiating therapy: Discontinue

Renal Dose

Renal Impairment CrCl <22 mL/min: 1 mg/day glimepiride PO prior to initiating glimepiride/pioglitazone; titrate conservatively to avoid hypoglycemia Base dose titration on fasting glucose levels CrCl >22 mL/min: 30 mg/2 mg or 30 mg/4 mg PO qDay initially

Contraindication

History of allergic reaction to sulfonamide derivative. Patient w/ established CHF (NYHA class III or IV). Not intended for treatment of type 1 DM or diabetic ketoacidosis.

Mode of Action

Pioglitazone, a thiazolidinedione, reduces blood glucose by improving target cell response to insulin w/o increasing pancreatic insulin secretion and is dependent on the presence of insulin for activity. Glimepiride, a sulfonylurea, stimulates insulin release from the pancreatic beta-cells. It also reduces glucose output from the liver and increases insulin sensitivity at peripheral target sites.

Precaution

Pioglitazone, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when is used in combination with insulin. Fluid retention may lead to or exacerbate congestive heart failure. Patients should be observed for signs and symptoms of congestive heart failure. If congestive heart failure develops, it should be managed according to current standards of care and discontinuation or dose reduction of must be considered. Lactation: Not known if crosses into breast milk, discontinue drug or breastfeeding

Side Effect

>10% Peripheral edema (6-12%),Upper respiratory tract infection (12-15%),Weight gain (9-13%),Hypoglycemia (13-16%) 1-10% Anemia (<2%),Limb pain (4-5%),Urinary tract infection (6-7%),Headache (4-7%),Diarrhea (4-6%),Nausea (4-5%)

Interaction

Increased plasma levels w/ CYP2C8 inhibitors (e.g. gemfibrozil) and CYP2C9 inhibitors (e.g. fluconazole). Decreased plasma levels w/ CYP2C8 inducers (e.g. rifampicin). Colesevelam may reduce the max plasma concentration and total exposure of glimepiride. Concominant use w/ oral miconazole may lead to severe hypoglycaemia.

Buy Dieta Plus 2 from Arogga

In Bangladesh, you can get the original Dieta Plus 2. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Dieta Plus 2 in Bangladesh?

The latest price of Dieta Plus 2 in Bangladesh is 11.62৳. You can buy Dieta Plus 2 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Dieta Plus 2.
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CONSULT YOUR DOCTOR
Dieta Plus 2 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Dieta Plus 2 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Monitor the breastfed baby’s blood sugar during treatment with Dieta Plus 2
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CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
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CAUTION
Dieta Plus 2 should be used with caution in patients with kidney disease. Dose adjustment of Dieta Plus 2 may be needed. Please consult your doctor. Use of Dieta Plus 2 is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
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CAUTION
Dieta Plus 2 should be used with caution in patients with liver disease. Dose adjustment of Dieta Plus 2 may be needed. Please consult your doctor. Use of Dieta Plus 2 is not recommended in patients with severe liver disease.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.