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Remicade
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Infliximab
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Remicade does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Remicade may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CAUTION
Remicade should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
CONSULT YOUR DOCTOR
It is not known whether Remicade alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CONSULT YOUR DOCTOR
There is limited information available on the use of Remicade in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Remicade in patients with liver disease. Please consult your doctor.
Medicine Overview of Remicade 100mg Injection
Introduction
Remicade is used for the treatment of various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). It reduces inflammation in these conditions by blocking TNF alpha. Remicade is given as an infusion (slow drip) into a vein under the supervision of a doctor. You will be monitored while you are given this medicine. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. Make sure that you turn up for all your injections as...
... Show moreUses of Remicade
- Rheumatoid arthritis
- Ankylosing spondylitis
- Psoriasis
- Psoriatic arthritis
- Ulcerative Colitis
- Crohn’s disease
Side effects of Remicade
Common
- Headache
- Sinus inflammation
- Upper respiratory tract infection
- Infusion reaction
- Abdominal pain
- Sore throat
How to use Remicade
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Remicade works
Remicade is a monoclonal antibody that blocks a protein in immune system called TNF (tumor necrosis factor) that causes inflammation (pain and swelling) in joints.
What if you forget to take Remicade?
If you miss a dose of Remicade, please consult your doctor.
Quick Tips
- Remicade is injected into a vein (intravenous infusion) under the supervision of a doctor. It is usually administered at 0, 2, 6 weeks and then once every 8 weeks.
- It may take some time before you start to feel better after getting this medicine. However, it is important that you do not miss any dose and show up for your next infusion as per the schedule advised by your doctor.
- Remicade can make it difficult for your body to fight infections. Inform your doctor if you notice any fever, cough, runny nose, rash, loose stools or flu-like symptoms.
- Inform your doctor if you have ever had tuberculosis or if you have been in close contact with someone who has or had tuberculosis. Your doctor may advise you certain tests to screen for tuberculosis before starting treatment with this medicine.
- Inform your doctor if you have or ever had the hepatitis B virus infection. Your doctor may test you for hepatitis B virus before starting treatment with this medicine.
- You may be advised regular blood tests to monitor blood counts while taking this medication.
Brief Description
Indication
Crohn's disease, Rheumatoid arthritis, Ulcerative colitis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis
Adult Dose
Intravenous Crohn's disease Adult: Initially, 5 mg/kg by infusion over at least 2 hr, repeated at 2 wk after 1st infusion. No further doses should be given if there is no response after 2 doses. Responders: Maintenance: 5 mg/kg at 6 wk after initial dose then 8 wkly thereafter. May be re-administered w/in 16 wk after last infusion if signs/symptoms recur. Rheumatoid arthritis Adult: In combination w/ methotrexate: Initially, 3 mg/kg by infusion over at least 2 hr, repeated at 2 wk and 6 wk after 1st infusion then 8 wkly thereafter. May increase dose in increments of 1.5 mg/kg...
... Show moreChild Dose
Intravenous
Crohn's disease
Child: 6-17 yr Initially, 5 mg/kg by infusion over at least 2 hr, repeated at 2 wk and 6 wk after 1st infusion then 8 wkly thereafter.
Ulcerative colitis
Child: 6-17 yr Initially, 5 mg/kg by infusion over 2 hr, repeated at 2 wk and 6 wk after 1st infusion then 8 wkly thereafter.
Contraindication
Patient w/ TB or other severe infections (e.g. sepsis, abscesses, opportunistic infections), moderate or severe heart failure (NYHA class III or IV).
Mode of Action
Infliximab is a chimeric monoclonal antibody which binds w/ high affinity to the soluble and transmembrane forms of tumour necrosis factor-α (TNF-α) thereby inhibiting binding of TNF-α to its receptors.
Precaution
Patient w/ mild heart failure (NYHA class I or II), history of blood dyscrasias, chronic or recurrent infection. Childn. Pregnancy and lactation. Patient Counselling This drug may cause dizziness, if affected, do not drive or operate machinery. Monitoring Parameters Monitor for signs and/or symptoms of infection, hypersensitivity reaction, lupus-like syndrome, heart failure, malignancy. Monitor vital signs every 2-10 min if reaction is noted during infusion. Perform hepatitis B virus screening prior to and hepatitis B virus carriers during and several mth after therapy; CBC w/ differential, LFTs.
Interaction
Increased risk of serious infection and neutropenia w/ anakinra or abatacept. Risk of clinical infections, including disseminated infections w/ concurrent admin of live vaccines.
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