Bortez 1 may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Bortez 1 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult...
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UNSAFE
Bortez 1 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
UNSAFE
Bortez 1 may cause side effects which could affect your ability to drive.
Bortez 1 might cause tiredness, dizziness, fainting, or blurred vision which may affect your ability to drive.
CAUTION
Bortez 1 should be used with caution in patients with severe kidney disease. Dose adjustment of Bortez 1 may be needed. Please consult your doctor.
Limited information is available on the use of Bortez 1 in these patients.
CAUTION
Bortez 1 should be used with caution in patients with liver disease. Dose adjustment of Bortez 1 may be needed. Please consult your doctor.
Medicine Overview of Bortez 1mg/vial Injection
Introduction
Bortez 1 is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.
Bortez 1 is given as an injection by a qualified medical professional. Your doctor will deci...
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Uses of Bortez 1
Multiple myeloma
Mantle-cell lymphoma
Side effects of Bortez 1
Common
Low blood platelets
Fatigue
Peripheral neuropathy (tingling and numbness of feet and hand)
Psychiatric disturbances
Nausea
Vomiting
Loss of appetite
Fever
Anemia (low number of red blood cells)
Diarrhea
Decreased appetite
Decreased white blood cell count (neutrophils)
Constipation
How to use Bortez 1
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Bortez 1 works
Bortez 1 is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number of proteins in the cancer cells leading to their death.
What if you forget to take Bortez 1?
If you miss a dose of Bortez 1, please consult your doctor.
Quick Tips
Before taking bortezomib, consult your doctor if you have any of the following disease conditions: disease of liver, kidney, heart or infect...
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Drink plenty of fluids every day during your treatment with bortezomib.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Consult your doctor if you have signs of serious brain infection such as memory loss, trouble in thinking, difficulty with walking or loss o...
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Do not drive or operate machinery after taking bortezomib as it may cause tiredness, dizziness, fainting or blurred vision.
Brief Description
Indication
Mantle Cell Lymphoma, Multiple Myeloma,
Administration
IV or SC Preparation
Reconstitute vial with 0.9% NaCl
IV administration: Add 3.5 mL to vial for final concentration of 1 mg/mL
SC administration: 2...
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Adult Dose
Mantle Cell Lymphoma
Indicated for treatment of patients with mantle cell lymphoma as first-line in previously untreated patients or those who have r...
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Contraindication
Hypersensitivity. Child. Pregnancy and lactation.
Mode of Action
Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26-S proteasome. It prevents targeted proteolysis that affects multiple ...
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Precaution
Hepatic or renal impairment; history of syncope, orthostatic hypotension; dehydration. Impairs ability to drive or operate machinery. Monitor for symp...
Pregnancy
Based on mechanism of action and findings in animals, therapy can cause fetal harm when administered to a pregnant woman; there are no st...
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Interaction
Concurrent use of amiodarone, antivirals, isoniazid, nitrofurantoin, statins may increase the chance of peripheral neuropathy. Concurrent use of antih...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.