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Gisin
Nipa Pharmaceuticals Ltd.
Generic: Gentamicin 0.3% E/E prep
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Gisin is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Gisin is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Gisin may cause side effects which could affect your ability to drive.
Medicine Overview of Gisin 0.30% Eye/Ear Drops
Introduction
Gisin is an antibiotic instilled in the eye to treat bacterial infections of the eye (eg. conjunctivitis). Additionally, it may be instilled in the ear to treat bacterial infections of the ear (eg. otitis externa). Gisin also helps to prevent an infection after eye/ear injury or surgery. It fights the infection by stopping the growth of bacteria. This helps to resolve your symptoms and cure the underlying infection. Follow your doctor's instructions precisely for administering this medicine in the eye/ear. Wait for at least 5 minutes before applying any other medication to the same eye/ear. It should be used regularly...
... Show moreUses of Nicogenta Eye/Ear Drops
- Bacterial eye / ear infections
Side effects of Nicogenta Eye/Ear Drops
Common
- Limited data available
How to use Nicogenta Eye/Ear Drops
This medicine is for external use only.Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye/ear without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid or ear. Wipe off extra liquid.
How Nicogenta Eye/Ear Drops works
Gisin is an antibiotic. It stops bacterial growth in the eye/ear by preventing synthesis of essential proteins required by bacteria to carry out vital functions. This treats your eye/ear infection.
What if you forget to take Nicogenta Eye/Ear Drops?
If you miss a dose of Gisin, please consult your doctor.
Quick Tips
- Nicogenta 0.25% Eye/Ear Drops helps treat bacterial infections of the eye/ear.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Do not touch the tip to any surface, or to your eye/ear, to avoid contamination.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye/ear to avoid dilution.
- Inform your doctor if your symptoms do not improve within two days of starting treatment, if they get worse during treatment or if you get another eye /ear infection.
- Make sure to use within 4 weeks of opening the bottle.
Brief Description
Indication
Superficial ophthalmic infections, Otitis externa,
Adult Dose
Ophthalmic
Superficial ophthalmic infections
Adult: As eye drops: Instill 1-2 drops into affected eye up to 6 times daily.
For severe infections, initially, 1-2 drops every 15 min, reducing the frequency gradually as the infection is controlled.
As eye oint: Place a small amount into the conjunctival sac 2-3 times daily.
Otic/Aural
Otitis externa
Adult: As ear drops: Instill 2-3 drops in the affected ear 3-4 times a day and at night.
Child Dose
Ophthalmic
Superficial ophthalmic infections
Child: As eye drops: Instill 1-2 drops into affected eye up to 6 times daily.
For severe infections, initially, 1-2 drops every 15 min, reducing the frequency gradually as the infection is controlled.
As eye oint: Place a small amount into the conjunctival sac 2-3 times daily.
Otic/Aural
Otitis externa
Child: As ear drops: Instill 2-3 drops in the affected ear 3-4 times a day and at night.
Contraindication
History of hypersensitivity to aminoglycoside; pregnancy; hepatic impairment, perforated ear drum.
Mode of Action
Gentamicin is an aminoglycoside that binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective.
Precaution
Concurrent use of neuromuscular blocking agents; myasthenia gravis, parkinsonism; conditions predisposing to ototoxicity and nephrotoxicity; lactation. Monitor plasma concentrations of gentamicin in patients receiving high doses or prolonged courses, in infants, elderly, patients with renal impairment, cystic fibrosis or significant obesity. Monitor auditory and renal functions.
Lactation: safety in nursing infants unknown
Side Effect
Allergic contact dermatitis, Transient irritation, burning, stinging, Increased redness, lacrimation
Interaction
Additive effect w/ other neurotoxic and/or nephrotoxic drugs including cephalosporins, methicillin, amphotericin B, ciclosporin, cisplatin, potent diuretics (e.g. ethacrynic acid, furosemide) and neuromuscular blocking agents (e.g. succinylcholine, tubocurarine). May potentiate the effect of anticoagulants (e.g. warfarin, phenindione). May antagonise the effect of neostigmine and pyridostigmine. Increased risk of hypocalcaemia w/ bisphosphonates. Increased risk of neuromuscular blockade w/ botulinum toxin. Indometacin may increase the plasma concentration of gentamicin in neonates.
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