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Servizid

Tablet-(300mg)
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Nevian Lifescience PLC

Generic: Isoniazid

1 Tablet
৳ 0.58
৳ 0.61
5% OFF

Medicine Overview of Servizid 300mg Tablet

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Introduction

Servizid is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It works by killing the bacteria that cause tuberculosis. Servizid should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. It may cause tingling and numbness of feet and hand (peripheral neuropathy) as a side effect of this medicine. Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and need dose modification. Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Servizid

  • Tuberculosis (TB)

Side effects of Servizid

Common
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Hepatitis (viral infection of liver)
  • Jaundice

How to use Servizid

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Servizid is to be taken empty stomach. Avoid Servizid with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Servizid works

Servizid is an antibiotic. It works by killing the bacteria that causes tuberculosis.

What if you forget to take Servizid?

If you miss a dose of Servizid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • Your doctor has prescribed Servizid to cure your infection and improve symptoms.
  • It is best taken on an empty stomach.
  • You must also take a vitamin B6 supplement while on Servizid.
  • Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

Brief Description

Indication

Tuberculosis

Administration

Should be taken on an empty stomach. Best taken on an empty stomach 1 hr before or 2 hr after meals. May be taken w/ meals to reduce GI discomfort.

Adult Dose

Oral Active Tuberculosis Disease 5 mg/kg PO qDay, not to exceed 300 mg qDay 15 mg/kg PO up; not to exceed 900 mg 1-3 times/week Used in multi-drug regimen containing rifampin (or ribabutin or rifapentin), pyrazinamide, and ethambutol Latent Tuberculosis Infection Treatment of latent TB infection greatly reduces the risk that TB infection will progress to acitve disease >30 kg: 300 mg PO qDay x9 months

Child Dose

Active Tuberculosis Disease 10-15 mg/kg PO qDay; not to exceed 300 mg/day OR 20-30 mg/kg (up to 900 mg) 2 times/week Used in multi-drug regimen Latent Tuberculosis Infection Treatment of latent TB infection greatly reduces the risk that TB infection will progress to acitve disease 10-15 mg/kg PO qDay; not to exceed 300 mg/day

Renal Dose

Renal impairment: Severe: Dose reduction may be needed.

Contraindication

Acute liver disease or history of hepatic damage during INH therapy; hypersensitivity.

Mode of Action

Isoniazid inhibits the synthesis of mycoloic acids in susceptible bacteria which results in loss of acid-fastness and disruption of bacterial cell wall. At therapeutic levels, it is bacteriocidal against actively growing intracellular and extracellular Mycobacterium tuberculosis organisms.

Precaution

Renal or hepatic impairment; convulsive disorders; history of psychosis; patients at risk of neuropathy or pyridoxine deficiency eg, diabetic, alcoholic, malnourished, uraemic, infected with HIV. Careful monitoring of hepatic function is necessary for black and hispanic women. Check hepatic function before and during treatment. Pregnancy and lactation. Lactation: distributed into milk but safe for nursing infants

Side Effect

>10% Mild incr LFTs (10-20%),Peripheral neuropathy (dose-related incidence, 10-20% incidence with 10 mg/kg/d) Loss of appetite,Nausea,Vomiting,Stomach pain,Weakness 1-10% Dizziness,Slurred speech,Lethargy,Progressive liver damage (increases with age; 2.3% in pts > 50 yo),Hyperreflexia <1% Agranulocytosis,Anemia,Megaloblastic anemia,Thrombocytopenia,Systemic lupus erythematosus,Seizure Potentially Fatal: Hepatotoxicity.

Interaction

Inhibit the hepatic metabolism of antiepileptics (e.g. carbamazepine, ethosuximide, primidone, phenytoin), benzodiazepines (e.g. diazepam, triazolam), chlorzoxazone, theophylline, disulfiram, sometimes leading to increased toxicity. Increased metabolism of enflurane, resulting in potentially nephrotoxic levels of fluoride. Increased concentrations and enhanced effects or toxicity of clofazimine, cycloserine and warfarin. Reduced absorption w/ Al-containing antacids. Increased risk of peripheral neuropathy w/ zalcitabine and stavudine.

Buy Servizid from Arogga

In Bangladesh, you can get the original Servizid. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Servizid in Bangladesh?

The latest price of Servizid in Bangladesh is 0.58. You can buy Servizid at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
Consuming alcohol while taking Servizid may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
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CONSULT YOUR DOCTOR
Servizid may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Servizid is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
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UNSAFE
Servizid may cause side effects which could affect your ability to drive. Servizid can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
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SAFE IF PRESCRIBED
Servizid is safe to use in patients with kidney disease. No dose adjustment of Servizid is recommended. However, talk to your doctor if you have any underlying kidney disease.
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CAUTION
Servizid should be used with caution in patients with liver disease. Dose adjustment of Servizid may be needed. Please consult your doctor. Use of Servizid is not recommended in patients with severe liver disease.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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