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Lapen 12 Lac
Jayson Pharmaceuticals Ltd.
Generic: Benzathine Penicillin
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Lapen 12 Lac does not cause any harmful side effects.
SAFE IF PRESCRIBED
Lapen 12 Lac is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Lapen 12 Lac is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Lapen 12 Lac may cause side effects which could affect your ability to drive.
CAUTION
Lapen 12 Lac should be used with caution in patients with kidney disease. Dose adjustment of Lapen 12 Lac may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Lapen 12 Lac in patients with liver disease. Please consult your doctor.
Medicine Overview of Lapen 12 Lac 12LacUnit Injection
Introduction
Lapen 12 Lac is an antibiotic used to treat a variety of bacterial infections. It is effective in treating sore throat and sexually transmitted diseases like Syphilis. This medicine is also used to prevent some bacterial infections such as Rheumatic fever. Lapen 12 Lac is a long-acting type of penicillin, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as an injection into the muscle under the supervision of a healthcare professional. It should be used regularly as per the schedule prescribed by your doctor. Do not skip any doses and finish the...
... Show moreUses of Lapen 12 Lac
- Bacterial infections
- Syphilis
- Prevention of rheumatic fever
Side effects of Lapen 12 Lac
Common
- Rash
- Allergic reaction
- Injection site reactions (pain, swelling, redness)
How to use Lapen 12 Lac
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Lapen 12 Lac works
Lapen 12 Lac is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
Quick Tips
- You have been prescribed Penidure LA 12 Injection for the treatment of bacterial infections.
- It is given by an injection into a vein or muscle, or via a drip into a vein.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Brief Description
Indication
Anthrax, Group A Strep. infections, Neurosyphilis, Fusobacterium infections, Diphtheria, Erysipeloid, Uncomplicated pneumococcal pneumonia, Rat bite fever, Rheumatic fever, Syphilis, Streptococcal pharyngitis
Adult Dose
Adult: IM: 0.3 to 1.2 million units up to 2.4 million units as a single dose repeated every five to seven days. Specific dosage schedule: Treatment of group-A beta-haemolytic streptococcal infections: A single intramuscular dose of 600,000 units. Prevention of rheumatic fever: Monthly injection of a single dose of 1.2 million units is the most effective regimen for preventing further attacks of rheumatic fever. Treatment of acute otitis media: A single injection of 600,000 units. Treatment of syphilis: Early syphilis- 2.4 million units as a single dose. Late syphilis- 2.4 million units weekly for three successive weeks. Neurosyphilis- Benzylpenicillin, intravenously,...
... Show moreChild Dose
Child: IM 50,000 U/kg for newborns and infants,
Child: IM 50,000 U/kg for newborns and infants,
children 60 lb: 900,000 U
1 dose for treatment
Contraindication
Hypersensitivity to penicillins or cephalosporins. IM inj (ischaemic reactions may occur).
Mode of Action
Benzathine benzylpenicillin has the same antimicrobial action as benzylpenicillin which exerts its bactericidal action on growing and dividing bacteria by inhibiting bacterial cell wall synthesis. IM admin results in a prolonged effect, but because of its relatively low blood concentrations, its use should be restricted to microorganisms that are highly susceptible to it.
Precaution
Very high doses in poor renal function (risk of neurotoxicity) or heart failure. Avoid contact, skin sensitization may occur. Monitor serum potassium concentration, renal and haematological status. Spirochete infections particularly syphilis; suprainfection with penicillin-resistant organisms with prolonged use; avoid intrathecal route.
Lactation: Excreted into breast milk, caution advised
Side Effect
Hypersensitivity reactions including uticaria; fever; joint pains; rashes; angioedema; serum sickness-like reactions; haemolytic anaemia; interstitial nephritis; neutropenia; thrombocytopenia; CNS toxicity including convulsions; diarrhoea; antibiotic-associated colitis.
Potentially Fatal: Anaphylaxis
Pregnancy Category Note
Pregnancy Category: B
Lactation: Excreted into breast milk, caution advised
Interaction
Probenecid prolongs T1/2 of benzathine benzylpenicillin. Bacteriostatic drugs e.g. chloramphenicol, tetracyclines; other antibacterials; anticoagulants.
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