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Pamulin
Navana Pharmaceuticals Ltd.
Generic: Retapamulin 1% Topical
Safety Advices
বাংলা
English
SAFE IF PRESCRIBED
Pamulin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Pamulin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
The baby's skin should not come into direct contact with the treated area of skin. Water-miscible cream/gel is preferred over ointments as an ointment may expose the baby to harmful effects.
Medicine Overview of Pamulin 1% Ointment
Introduction
Pamulin is an antibiotic. It is used in the treatment of bacterial skin infections. It stops the growth of bacteria that cause infections and thus relieves your symptoms. Pamulin is for external use only. You should use it in the dose and duration as advised by your doctor. The affected area should be clean and dry before application of the ointment. You must wash your hands thoroughly before and after applying this medicine. To avoid relapse, continue the use of this medicine even if symptoms begin to clear up. Do not cover the area being treated with airtight dressings such...
... Show moreUses of Pamulin
- Bacterial skin infections
Side effects of Pamulin
Common
- Skin irritation
How to use Pamulin
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Pamulin works
Pamulin stops the growth of bacteria that cause infections.
Quick Tips
- Pamulin treats minor skin infections caused by certain types of bacteria.
- Apply it gently to the infected area of skin twice a day for five days.
- Avoid contact with your eyes, nose, mouth or genital areas. Rinse off with water if accidental contact occurs.
- Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor.
- Stop using it and inform your doctor if you notice worsening of the infection or if you develop increased redness and irritation.
- Dispose off any remaining medicine seven days after opening.
- Consult your doctor immediately if there is no improvement in your infection after two to three days of treatment.
Brief Description
Indication
Impetigo, Bacterial skin infections
Adult Dose
Topical/Cutaneous
Impetigo; Bacterial skin infections due to meticillin-susceptible, Staphylococcus aureus and Streptococcus pyogenes
Adult: As 1% ointment: Apply onto affected area bid for 5 days.
Re-evaluate if there is no response after 3 days of treatment.
Total treatment area: <100 cm2 total body surface area.
Child Dose
Topical/Cutaneous
Impetigo; Bacterial skin infections due to meticillin-susceptible, Staphylococcus aureus and Streptococcus pyogenes
Child: As 1% ointment: >9 mth: Apply onto affected area bid for 5 days. Total treatment area: <2% of total body surface area.
Contraindication
Hypersensitivity.
Mode of Action
Retapamulin is a pleuromutilin antibacterial isolated from the fungus Clitopilus passeckerianus. It is a bacteriostatic agent that works by inhibiting biosynthesis of bacterial protein by binding at protein L3 on the ribosomal 50S subunit. It also inhibits peptidyl transfer and blocks P-site interactions at this site, thus preventing the formation of active 50S ribosomal subunits.
Precaution
Discontinue use if skin irritation occurs. Prolonged use may result in fungal or bacterial superinfection. Re-evaluate if there is no response within 3 days. Children <9 mth. Pregnancy, lactation.
Lactation: use caution
Side Effect
1-10%
Application site irritation (2%)
Headache, pyrexia, pruritus, eczema, diarrhoea.
Interaction
Concurrent application w/ other topical products to the same skin area is not recommended.
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