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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Norditropin Simplexx.
CONSULT YOUR DOCTOR
Norditropin Simplexx may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Norditropin Simplexx is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SAFE
Norditropin Simplexx does not usually affect your ability to drive.
CONSULT YOUR DOCTOR
There is limited information available on the use of Norditropin Simplexx in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Norditropin Simplexx in patients with liver disease. Please consult your doctor.
Medicine Overview of Norditropin Simplexx 10mg/1.5ml Injection
Introduction
Norditropin Simplexx is a medicine that is identical to the main form of the naturally occurring human growth hormone. It is used to treat children with growth failure due to inadequate secretion of endogenous growth hormone (GH). It is used to treat short stature in adults also. Norditropin Simplexx is given as an injection into the skin under the supervision of a doctor. Your doctor or nurse will help you to learn the exact method of self-administration. You should receive appropriate training and instructions from the physician before using it. The dose and how often you take it depends on...
... Show moreUses of Norditropin Simplexx
- Growth failure due to growth hormone deficiency
Side effects of Norditropin Simplexx
Common
- Injection site reactions (pain, swelling, redness)
- Headache
- Rash
How to use Norditropin Simplexx
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Norditropin Simplexx works
Norditropin Simplexx has the same structure as natural human growth hormone which is required for the growth of bones and muscles. It also helps the fat and muscle tissues to develop in the right proportion.
Quick Tips
- Norditropin Simplexx helps treat deficiency of growth hormone.
- It is given by an injection into the fatty tissue just under your skin by your doctor.
- Inform your doctor if you have diabetes or if you are receiving treatment with thyroid hormones.
- Inform your doctor if you start to limp due to pain in your hip, while on treatment with this medicine.
- Inform your doctor if you are pregnant or breastfeeding.
Brief Description
Indication
Growth hormone deficiency, HIV-associated wasting or cachexia, Short bowel syndrome
Adult Dose
Growth Hormone Deficiency Weight-based dosing Not to exceed 0.004 mg/kg/day SC initially for 6 weeks; may increase up to 0.016 mg/kg/day maximum Nonweight-based dosing 0.2 mg/day (0.15-0.3 mg/day range) SC initially; may increase every 1-2 months by 0.1-0.2 mg/day based on clinical response and/or serum IGF-I levels Short-bowel Syndrome 0.1 mg/kg/day SC (rotating injection sites to avoid lipodystrophy) for 4 weeks; may increase up to 8 mg/day maximum; treatment exceeding 4 weeks not studied HIV-associated Wasting or Cachexia 0.1 mg/kg/day SC at bedtime (rotating injection sites to avoid lipodystrophy) up to 6 mg/day; Alternatively: >55 kg: 6 mg/day SC 45-55...
... Show moreChild Dose
Growth Hormone Deficiency
0.024-0.034 mg/kg/day SC 6-7 days/week
Small for Gestational Age
Not to exceed 0.067 mg/kg/day SC
Nooman Syndrome With Growth Hormone Deficiency
Not to exceed 0.066 mg/kg/week SC
Turner Syndrome With Growth Hormone Deficiency
Not to exceed 0.067 mg/kg/day SC
Contraindication
Acute critical illness due to heart or abdominal surgery, multiple accidental trauma or respiratory failure; active neoplasms, proliferative or preproliferative diabetic retinopathy; lactation; patients with closed epiphyses. Intracranial lesions. Patients with Prader-Willi syndrome who are severely obese or have severe respiratory impairment.
Mode of Action
Somatropin is a synthetic human growth hormone of recombinant DNA origin. It stimulates skeletal and soft tissue growth by promoting cell division, amino acid uptake and protein synthesis. It also possesses both insulin-like and diabetogenic effects.
Precaution
Monitor thyroid function; benign intracranial hypertension. DM; may require dose reduction in insulin. Pregnancy. Discontinue treatment if there is evidence of tumour growth. Monitoring in patients with scoliosis is recommended due to risk of progression of scoliosis.
Side Effect
Hypothyroidism, peripheral oedema; headache; muscle and joint pain; benign intracranial hypertension. Loss of glycaemic control in diabetics, New onset type 2 diabetes mellitus, Scoliosis,Hypoglycemia,Seizures,Pancreatitis,Exacerbation of psoriasis,Hematuria,Hematoma,Leukemia,Papilledema, Arthralgia,Hyperlipidemia,Otitis media,Ear disorders,Respiratory Illness,Urinary tract infection.
Interaction
High doses of corticosteroid may inhibit growth-promoting effects of somatropin.