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Firmagon

Injection-(120mg)
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Radiant Pharmaceuticals Ltd.

Generic: Degarelix

1 x 2's Pack
৳ 20453.26
৳ 21775
6% OFF

Medicine Overview of Firmagon 120mg Injection

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Introduction

Firmagon is used in the treatment of advanced prostate cancer. It works by lowering the amount of testosterone produced in the body and restricts the growth of a cancer cell. Firmagon is given as an injection under the skin only under the supervision of a doctor. Do not try to self inject the medicine as it might enhance the chances of an accident or get injected into the veins. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include Injection site reactions (pain, swelling, redness), weight gain, hot flashes, increased liver enzyme, and low sexual desire. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. If you notice dizziness or trouble sleeping, then better to avoid driving or machinery work. Before taking this medicine, tell your doctor if you have ever had heart disease, or diabetes or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may check for prostate specific antigen (PSA) level in your blood, to know treatment is working or not.

Uses of Firmagon

  • Prostate cancer

Side effects of Firmagon

Common
  • Injection site reactions (pain, swelling, redness)
  • Weight gain
  • Hot flashes
  • Increased liver enzymes
  • Low sexual desire
  • Erectile dysfunction

How to use Firmagon

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Firmagon works

Firmagon lowers the amount of testosterone (a male hormone) produced by the body. This may slow or stop the spread and growth of prostate cancer cells that need testosterone to grow.

What if you forget to take Firmagon?

If you miss a dose of Firmagon, please consult your doctor.

Quick Tips

  • Firmagon helps in the treatment of advanced hormone-dependent prostate cancer.
  • It is give by injection under the skin (subcutaneously), usually in the stomach area.
  • It may cause dizziness and blurred vision. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It may cause hot flashes. Try wearing loose clothing and avoid alcohol, caffeine, and spicy foods.
  • Inform your doctor if you are diabetic or have problems with your heart, kidney or liver.
  • Your doctor may check the level of prostate specific antigen (PSA) in your blood. This is done to monitor how well Firmagon is working for you. A decrease in PSA levels is usually a sign that your treatment is working.

Brief Description

Indication

Hormone-dependent Advanced Prostate Carcinoma (Stage D)

Administration

Initiation pack contains 2 vials each with 120 mg per vial & 6 mL sterile water for injection diluent Withdraw 3 mL of sterile water for injection diluent (supplied) & add to 1 of the 2 vials, swirl to mix - keep vial vertical at all times, do not shake Inject SC in abdomen within 1 hour of reconstitution Repeat for 2nd injection and use different injection site Maintenance pack contains 1 vial of 80 mg per vial & 4.2 mL sterile water for injection diluent Use 4.2 mL to reconstitute, withdraw 4 mL for dose of 80 mg

Adult Dose

Subcutaneous Advanced prostate cancer Adult: Loading dose: As 40 mg/mL solution: 240 mg (given as 2 separate injections of 120 mg). Maintenance: As 20 mg/mL solution: 80 mg once every 28 days, starting 28 days after the initial dose. Doses are administered in the abdominal area. Hepatic Impairment Mild-to-moderate: Dose adjustment not necessary Severe: Safety and efficacy not established; use caution

Renal Dose

Renal Impairment >50 mL/min: Dose adjustment not necessary <50 mL/min: Use caution

Contraindication

Hypersensitivity. Pregnancy and lactation.

Mode of Action

Degarelix, a synthetic decapeptide, reversibly and competitively binds to gonadotropin-releasing hormone (GnRH) receptors in the anterior pituitary gland, thereby decreasing secretion of luteinising hormone (LH) and follicle stimulating hormone (FSH), and subsequently reducing testicular androgen synthesis.

Precaution

Patient with congenital long QT syndrome, history of or risk factors for QT prolongation (e.g. cardiac failure, electrolyte imbalance) and CV disease; diabetes, risk factors for low BMD. Moderate to severe renal (CrCl <50 mL/min) and severe hepatic impairment. Lactation: excretion in milk unknown/not recommended

Side Effect

>10% Hot flashes (26%) Injection site erythema (17%) Injection site pain (28%) Weight gain (11%) Elevated liver enzymes (10%) 1-10% (selected) Arthralgia Back pain Fatigue HTN Injection site induration/swelling

Pregnancy Category Note

Pregnancy Category: X Lactation: excretion in milk unknown/not recommended

Interaction

Increased risk of QT prolongation with class IA (e.g. disopyramide) or class III (e.g. amiodarone) antiarrhythmics, antipsychotics, methadone and moxifloxacin.

Buy Firmagon from Arogga

In Bangladesh, you can get the original Firmagon. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Firmagon in Bangladesh?

The latest price of Firmagon in Bangladesh is 20453.26৳. You can buy Firmagon at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CAUTION
Caution is advised when consuming alcohol with Firmagon. Please consult your doctor.
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UNSAFE
Firmagon is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
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CONSULT YOUR DOCTOR
Information regarding the use of Firmagon during breastfeeding is not available. Please consult your doctor.
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UNSAFE
Firmagon may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Firmagon in patients with kidney disease. Please consult your doctor. A cautious use of Firmagon is advised in patients with severe kidney disease.
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CAUTION
Firmagon should be used with caution in patients with severe liver disease. Dose adjustment of Firmagon may be needed. Please consult your doctor. No dose adjustment is recommended for patients with mild to moderate liver disease. Regular monitoring of testosterone levels is advised.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.