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Neocin Plus
Opsonin Pharma Limited
Generic: Bacitracin Zinc + Neomycin Sulphate + Polymixin B topical
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Neocin Plus may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Neocin Plus is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medicine Overview of Neocin Plus 3.5mg+400IU+5000IU/gm Ointment
Introduction
Neocin Plus is a combination medicine. It is used to treat various types of fungal skin infections. It minimizes symptoms of skin infection such as redness, swelling, itching, etc., by acting against the infection-causing microorganisms. Neocin Plus is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after applying the medicine. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several...
... Show moreUses of Neocin Plus
- Bacterial skin infections
Side effects of Neocin Plus
Common
- Application site reactions (burning, irritation, itching and redness)
How to use Neocin Plus
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.
How Neocin Plus works
Neocin Plus is a combination of three antibiotics: Bacitracin, Neomycin and Polymyxin B. These antibiotics work by killing the bacteria or stopping their growth on the skin. Together, they treat your skin infection effectively.
Quick Tips
- Neocin Plus helps treat bacterial skin infections.
- Use it once or twice daily, or as advised by your doctor. Treatment should be continued until at least two days after the condition has resolved.
- Do not apply it to broken skin and take care to avoid getting it in your eyes, nose or mouth.
- Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
- It may cause temporary burning, itching or a redness at application site. This is usually mild. Consult your doctor if you experience a more severe reaction.
- Do not use it more often or for longer than advised by your doctor. Inform your doctor if your skin problem does not improve even after seven days of treatment.
Brief Description
Indication
Minor cuts, Scrapes, Burns, Eczematoid dermatitis, Neurodermatitis, Eczema, Anogenital pruritus, Impetigo, Contact dermatitis, Bacterial skin infections.
Adult Dose
Treatment/Prophylaxis Superficial Skin Infection
Apply topically 3 times daily.
Child Dose
Treatment/Prophylaxis Superficial Skin Infection
Apply topically 3 times daily.
Contraindication
Hypersensitivity
Mode of Action
Neomycin, an aminoglyoside with antimicrobial spectrum similar to gentamicin, binds to the 30S subunits of the bacterial ribosome, inhibiting protein synthesis and thereby disrupting DNA synthesis. It is active against many gram-negative aerobes and against some strains of staphylococci. Bacitracin, on the other hand, inhibits bacterial cell wall synthesis and is active against many gram-positive bacteria (e.g. staphylococci, streptococci, corynebacteria and clostridia) and some gram-negative species (e.g. Neisseria and Haemophilus influenzae). They are often found in combinations in topical preparations as broad spectrum antibacterial agents. Polymyxin B disrupts the bacterial cytoplasmic membrane of mostly gm-ve organisms allowing leakage of intracellular...
... Show morePrecaution
Allergic cross-reactions may occur which could prevent the use of any or all of the following antibiotics for the treatment of future infections: kanamycin, paromomycin, streptomycin, and possibly gentamicin.
Lactation: unknown if distributed in breast milk
Side Effect
>10%
Allergic contact dermatitis (60%)
Pregnancy Category Note
Pregnancy Category: C
Lactation: unknown if distributed in breast milk
Interaction
Bacitracin Zinc: Increased risk of nephrotoxicity when used with other nephrotoxic drugs. May enhance the action of neuromuscular-blocking agents. Neomycin Sulphate: Additive nephrotoxic and neurotoxic effect w/ other aminoglycosides (e.g. paromomycin), bacitracin, cisplatin, vancomycin, amphotericin B, polymyxin B, colistin and viomycin. Enhanced toxicity w/ potent diuretics (e.g. ethacrynic acid, furosemide). May impair the absorption of other drugs (e.g. phenoxymethylpenicillin, digoxin, methotrexate and some vit). May reduce the efficacy of OCs. May enhance the effect of acarbose. May enhance the effect of non-depolarising muscle relaxants. May antagonise the parasympathomimetic effect of neostigmine and pyridostigmine. May increase the risk of hypocalcaemia in...
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