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Cotadex
Monicopharma Limited
Generic: Dexamethasone 0.1% + Tobramycin 0.3%
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Cotadex is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Cotadex is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Cotadex may cause side effects which could affect your ability to drive.
Cotadex may cause dizziness (vertigo). Changes in your eyesight or muscle weakness may also happen. This may affect your driving ability.
Medicine Overview of Cotadex 0.1%+0.3% Eye Drop
Introduction
Cotadex is a prescription medicine having a combination of medicines that is used to treat bacterial eye infections. It stops the growth of bacteria and helps in relieving redness, itching and swelling. Cotadex is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening....
... Show moreUses of Cotadex
- Bacterial infections
Side effects of Cotadex
Common
- Burning sensation
How to use Cotadex
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Cotadex works
Cotadex is a combination of two medicines: Dexamethasone and Tobramycin. Dexamethasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen and itchy. Tobramycin is an antibiotic. It stops bacterial growth in the eye by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.
Quick Tips
- Toba DM Eye Drops is used for the treatment of bacterial skin infections.
- It should be applied to the affected areas as a thin film, two or three times daily, or as advised by your doctor.
- Do not use it more often or for longer than advised by your doctor.
- Do not apply it to broken skin and avoid getting it in your eyes, nose or mouth.
- Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
- It may cause temporary burning, itching or a redness at application site. This is usually mild. Consult your doctor if you experience a more severe reaction.
- Inform your doctor if your skin problem hasn't improved after seven days of treatment.
Brief Description
Indication
Bacterial eye infections, Ocular inflammation, Pink eye
Adult Dose
Ophthalmic
Ocular inflammation with suspected or confirmed bacterial infection
Adult: As Eye Drops: 1-2 drops instilled into the conjunctival sac(s) 4-6 hrly. Dosage may be increased to every 2 hrly during the initial 24-48 hr, decrease frequency gradually as improvement seen.
As Ointment: Apply about ½ inch of ointment into the conjunctival sac(s) up to 3-4 times daily.
Child Dose
Ophthalmic
Ocular inflammation with suspected or confirmed bacterial infection
2 years
As Eye Drops: 1-2 drops instilled into the conjunctival sac(s) 4-6 hrly. Dosage may be increased to every 2 hrly during the initial 24-48 hr, decrease frequency gradually as improvement seen.
As Ointment: Apply about ½ inch of ointment into the conjunctival sac(s) up to 3-4 times daily.
Contraindication
Viral infections of corneal and conjunctiva (e.g. epithelial herpes simplex keratitis, vaccinia, varicella). Mycobacterial or fungal infection of the eye.
Mode of Action
Tobramycin, an aminoglycoside antibiotic, has actions similar to that of gentamicin and is active against Staphylococci, Streptococci, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus influenzae and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species. Dexamethasone, a synthetic fluorinated corticosteroid, has mainly glucocorticoid activity and suppresses inflammatory response.
Precaution
Pregnancy and lactation. Avoid prolonged use, monitor intraocular pressure routinely. Safety and effectiveness in children <2 yr not established.
Lactation: Excretion in milk unknown; use with caution
Side Effect
Hypersensitivity reactions, lid itching and swelling, conjunctival erythema, increase in intraocular pressure, glaucoma, optic nerve damage, posterior subcapsular cataract formation and delayed wound healing. Secondary infections especially after prolonged use.
Pregnancy Category Note
Pregnancy Category: C
Lactation: Excretion in milk unknown; use with caution
Interaction
Antagonistic effect w/ neostigmine and pyridostigmine. May potentiate the effect of warfarin and phenindione.
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