The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.
Ophthalmic
Inflammatory eye disorders
Adult: Instill 1-2 drops of a 1% solution up to 4 times daily.
Ointment: as required.
Eye refraction
Adult: Instill 1 drop of a 1% solution bid for 1-2 days before the procedure, or on a single occasion 1 hr before the procedure.
Child Dose
Ophthalmic
Inflammatory eye disorders
Child: As sulfate: Instill 1 drop of a 1% solution up to tid.
Ointment: as required.
Eye refraction
Child: As sulfate: Instill 1 or 2 drops of a 0.5% soln (or 1 drop of a 1% solution) bid for 1-3 days before the procedure, with a further dose given 1 hr before the procedure.
Contraindication
Narrow angle glaucoma.
Mode of Action
Atropine is an anticholinergic agent which competitively blocks the muscarinic receptors in peripheral tissues. It also has mydriatic and cycloplegic effect.
Precaution
Toxic systemic reaction may occur in the very young & very old.
Lactation: Trace amounts enter breast milk; use with caution (AAP Committee states "compatible with nursing")
Side Effect
Eye drops: Systemic toxicity esp in children, on prolonged use may lead to irritation, hyperaemia, oedema, dry eyes, vascular congestion, dermatitis, blurred vision and conjunctivitis. Increased intraocular pressure.
Pregnancy Category Note
Pregnancy Category: C
Lactation: Trace amounts enter breast milk; use with caution (AAP Committee states "compatible with nursing")
Interaction
Additive anticholinergic effects with quinidine, antidepressants and some antihistamines.
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