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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Gemzar

Name: Gemzar 1gm/vial Injection
Brand: Eli Lilly and Company
SKU: 25138
Price: 7937.39 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Injection - (1gm/vial)

Eli Lilly and Company

Generic: Gemcitabine

Safety Advices

বাংলা

English

UNSAFE

Gemzar may cause excessive drowsiness with alcohol.

CONSULT YOUR DOCTOR

Gemzar is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

UNSAFE

Gemzar is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

UNSAFE

Gemzar may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

CONSULT YOUR DOCTOR

There is limited information available on the use of Gemzar in patients with kidney disease. Please consult your doctor. Kidney function tests are advised before taking this medicine and regular monitoring is also recommended after the treatment.

CONSULT YOUR DOCTOR

There is limited information available on the use of Gemzar in patients with liver disease. Please consult your doctor.

Medicine Overview of Gemzar 1gm/vial Injection

Introduction

Gemzar is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer, and ovarian cancer. Gemzar is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you...

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Uses of Gemzar

Non-small cell lung cancer
Breast cancer
Pancreatic cancer
Urinary bladder cancer
Ovarian cancer

Side effects of Gemzar

Common

Nausea
Vomiting
Loss of appetite
Hair loss
Low blood platelets
Allergic reaction
Breathlessness
Decreased white blood cell count
Increased liver enzymes
Anemia (low number of red blood cells)
Flu-like symptoms
Blood in urine
Skin rash
Protein in urine

How to use Gemzar

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Gemzar works

Gemzar interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Quick Tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.

Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Brief Description

Indication

Lung cancer, pancreatic cancer, bladder cancer, breast cancer, ovarian carcinoma

Administration

IV Preparation Reconstitute 200 mg vial with 5 mL 0.9% NaCl OR 1000 mg vial with 25 mL 0.9% NaCl IV Administration For IV infusion only Concentrated injection (10 mg/mL) must be diluted to 2 mg/mL prior to administration Infuse over 30 min Avoid rapid infusions

Adult Dose

Pancreatic Cancer Indicated as first-line treatment for locally advanced (nonresectable Stage II or Stage III) or metastatic (Stage IV) adenocarcinoma of the pancreas 1000 mg/m² IV infusion over 30 minutes once/week x7 weeks; rest 1 week, THEN 1000 mg/m² IV on Days 1, 8, and 15 of each 28-day cycle Various regimens exist including monotherapy and in combination with other chemotherapy agents (eg, erlotinib, paclitaxel protein bound, capecitabine) Non-small Cell Lung Cancer 1000 mg/m² IV infusion over 30 minutes on days 1, 8, and 15 of each 28-day cycle, OR 1250 mg/m² IV infusion over 30 minutes on days 1...

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Contraindication

Concurrent radical radiotherapy; pregnancy, lactation; hypersensitivity.

Mode of Action

Gemcitabine is a synthetic pyrimidine nucleoside and cytarabine analogue which is metabolised intracellularly to active diphosphate and triphosphate nucleosides. It inhibits DNA synthesis by inhibiting DNA polymerase and ribonucleotide reductase. It also induces apoptosis and is primarily active against cells in the S-phase, but may also arrest cells at the G1-S border.

Precaution

Children, hepatic and renal impairment. May impair ability to drive or operate machinery. Discontinue on 1st sign of microangiopathic haemolytic anaemia. Prolonged infusion time (>60 minutes) and more frequent than wkly dosing may increase toxicity. Monitor CBC before every dose. Increased risk of haemolytic uraemic syndrome and/or thrombocytcpenic purpura which may lead to irreversible renal failure. Lactation: not known if excreted in breast milk; do not nurse

Side Effect

>10% N/V (69%),Anemia (65%),Elev LFTs (68%),Neutropenia (63%),Leukopenia (62%),Pain (48%),Proteinuria (45%),Fever (41%),Hematuria (35%),Rash (30%),Thrombocytopenia (24%),Dyspnea (23%),Constipation (23%),Diarrhea (19%),Flu-like syndrome (19%),Hemorrhage (17%),BUN increased (16%),Infection (16%),Alopecia (15%),Edema (13%),Elev bilirubin (13%) 1-10% Paresthesia (2-10%),Creatinine increased (2-8%),Inj site reactions (4%),Bronchospasm (2%) Potentially Fatal: Oesophagitis and pneumonitis when given with radical radiotherapy to the thorax.

Interaction

May increase the anticoagulant effect of warfarin when used together.

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Gemzar

Injection - (1gm/vial)

Eli Lilly and Company

Generic: Gemcitabine

Additional Offers

Cashback

৳50

For purchasing above ৳5000+

Cashback

৳40

For purchasing above ৳4000+

Cashback

৳30

For purchasing above ৳3000+

Cashback

৳20

For purchasing above ৳2000+

Cashback

৳10

For purchasing above ৳1000+

Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

Gemzar

Medicine Overview of Gemzar 1gm/vial Injection

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