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Alendon
Beximco Pharmaceuticals Ltd.
Generic: Alendronic Acid (Alendronate)
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Alendon does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Alendon may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Alendon is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
If you are taking Alendon during breastfeeding, monitor baby's blood calcium levels during the first two months.
UNSAFE
Alendon may cause side effects which could affect your ability to drive.
Alendon is not expected to have any effects but in rare cases, it may cause dizziness, severe muscle, joint and bone pain and eye pain or inflammation. This may affect your ability to drive.
CAUTION
Alendon should be used with caution in patients with severe kidney disease. Dose adjustment of Alendon may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate kidney disease.
SAFE IF PRESCRIBED
Alendon is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Alendon may not be needed in these patients. Please consult your doctor.
Medicine Overview of Alendon 10mg Tablet
Introduction
Alendon is used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or use of steroids. Using this medicine can reduce your risk of breaking bones. Alendon is best taken without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished, even when you feel better. It may take several days to get the full benefit of this drug. Alendon is only part of...
... Show moreUses of Alendon
- Osteoporosis
Side effects of Alendon
Common
- Diarrhea
- Headache
- Heartburn
- Musculoskeletal (bone, muscle or joint) pain
How to use Alendon
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alendon is to be taken empty stomach.
How Alendon works
Alendon is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.
What if you forget to take Alendon?
If you miss a dose of Alendon, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- Your doctor has prescribed Alendon to make your bones stronger and lower the risk of fractures.
- Take it in the morning at least 30 minutes before eating or drinking anything.
- Maintain an upright posture for 30 minutes after taking the medication so the medicine does not irritate your food pipe.
- It may cause the amount of calcium in your blood to fall. Take calcium-rich food in your diet and have regular blood tests to monitor the level of calcium in your blood.
- It is important to look after your mouth and teeth while you are taking this medicine. Have regular dental check-ups and inform your dentist about taking Alendon.
Brief Description
Indication
Adult: PO Osteoporosis 10 mg/day or 70 mg once wkly.
Prevention of postmenopausal osteoporosis 5 mg/day or 35 mg once wkly.
Corticosteroid-induced osteoporosis 5 mg/day; up to 10 mg/day in women not on HRT treatment.
Paget's disease of bone 40 mg/day for 6 mth. May repeat after an interval of 6 mth if needed.
Administration
Concomitant iron, calcium supplements and antacids hinder alendronate absorption. Concomitant aspirin or NSAIDs may increase the incidence of adverse GI effects.
Adult Dose
Upper GI disorders (discontinue if symptoms worsen); history of ulcers, active GI bleeding. Correct vitamin D and calcium deficiency before starting therapy. To be taken half an hr before breakfast and remain upright for at least 30 minutes after admin. Not recommended for use in patients with CrCl <35 ml/min.
Lactation: Unknown whether drug is excreted in milk; use with caution.
Renal Dose
Alendronic acid reduces bone resorption by inhibiting the action of osteoclasts.
Mode of Action
Administration
Take only in morning, not at bedtime or before arising
Take tablet with full glass of water (6-8 oz) at least 30 minutes before first food or drink of day, in upright position
Administer oral solution with at least 2 ounces of water
Swallow with plain water only; mineral water, coffee, juice or other beverages severely reduces bioavailability
Swallow tablet whole; do not suck or chew
Do not lie down for 30 minutes after taking drug; sit or stand upright
Precaution
Osteopetrosis, postmenopausal osteoporosis, Paget's disease of bone.
Side Effect
Renal impairment:
CrCl (ml/min)
<35 Not recommended.
Pregnancy Category Note
>10%
Hypocalcemia, transient and mild (18%)
1-10%
Hypophosphatemia, transient and mild (10%),Abdominal pain (7%),Musculoskeletal pain (4.1%),Dyspepsia (3.6%),Nausea (3.6%),Constipation (3.1%),Diarrhea (3.1%),Flatulence (2.6%),Headache (2.6%),Acid regurgitation (2%),Esophagitis (1.5%),Abdominal distention (1%)
<1%
Alopecia,Diaphyseal femur fracture,Esophageal cancer,Flu like syndrome,Gastritis,Myalgia,Oropharyngeal ulceration,Pruritus,Rash,Taste perversion,Toxic epidermal necrolysis,Uveitis,Vertigo,Weakness
Interaction
Hypocalcaemia; oesophageal abnormalities and factors which delay oesophageal emptying; severe renal impairment; hypersensitivity; inability to stand or sit upright for ?30 min. Pregnancy, lactation.
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