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Skin and nail fungal infections, Tinea pedis, Tinea cruris, Tinea corporis, Candidiasis, Pityriasis versicolor
Adult Dose
Topical/Cutaneous Skin and nail fungal infections: Adult: Apply 2 or 3 times daily.
Onychomycosis: for 6 months. Tinea pedis & Dermatomycoses: for 4 weeks.
Child Dose
Tinea Corporis/Tinea Pedis
Apply to affected area q12hr for 4 weeks
Tinea Cruris
>2 years: Apply to affected area q12hr for 2 weeks
Candidiasis
Gently massage sufficient clotrimazole into affected and surrounding area q12hr; reconsider diagnosis if no improvement after 4 weeks
Tinea Versicolor
Gently massage sufficient clotrimazole into affected and surrounding area q12hr; reconsider diagnosis if no improvement after 4 weeks
Contraindication
Hypersensitivity.
Mode of Action
Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.
Precaution
Avoid contact with eyes upon topical application. Childn <3 yrs. Pregnancy, lactation.If local intolerance develops, consider withdrawal of the medicine and institution of appropriate therapy.
Lactation: Excretion in milk unknown; use with caution
Pregnancy
Small amounts of imidazoles may be absorbed systemically following topical and vaginal administration
Lactation
Excretion in milk unknown; use with caution
Interaction
Antagonism with polyene antibiotics.
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